Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 592 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05378841Recruiting
Surgery to reduce pain in finger osteoarthritis
This trial tests whether surgical “nerve disconnection” (joint denervation) can reduce pain from osteoarthritis in a finger joint. It focuses on people who have ongoing finger pain despite usual treatments for at least 3 months.
ParisAges 18 years+ - NCT06570291RecruitingPhase 3
Stem cell injection for knee osteoarthritis
This trial tests a new treatment using donor stem cells injected into the knee for people with moderate knee osteoarthritis. It aims to see if these cells can reduce pain and improve function.
Shanghai, ChinaAges 40–75 - NCT06814821Recruiting
Web-based rehabilitation after wrist surgery for osteoarthritis
This study tests a web-based rehabilitation program after certain wrist surgeries for osteoarthritis. It aims to help you recover better at home after your operation.
StockholmAges 18 years+ - NCT06782347Recruiting
Study on SilverSneakers benefits for seniors with osteoarthritis
This study looks at whether offering the free SilverSneakers exercise program helps seniors with hip or knee osteoarthritis feel better and stay active. It is for people who have not used SilverSneakers before.
Hershey, PennsylvaniaAges 65 years+ - NCT06779071Enrolling by invitationPhase 3
NPNP-001 injection for knee osteoarthritis pain
This study tests a new medicine called NPNP-001 for people with knee osteoarthritis who have not gotten enough relief from other treatments. The medicine is given as an injection into the knee to see if it can reduce pain and improve function.
SeoulAges 40 years+ - NCT06755697Recruiting
Comparing injection methods for knee osteoarthritis
This trial compares two ways to give dextrose injections for knee osteoarthritis: one into the joint space and one guided by MRI into the tissues around the knee. It aims to see which approach works better for pain and function.
TaipeiAges 45–80 - NCT06747494Recruiting
Comparing general vs spinal anesthesia for hip or knee replacement
This study compares two types of anesthesia (general and spinal) for people having a total hip or knee replacement. The goal is to see which approach is better for recovery and overall outcomes.
Miami, FloridaAges 18 years+ - NCT06744036Recruiting
Exercise and electrical stimulation for knee arthritis
This study tests whether adding a gentle electrical current (interferential therapy) to a personalized exercise program can reduce pain and improve function in people with knee osteoarthritis. If you have knee pain from arthritis and have not had physical therapy or certain injections in the past six months, you may be able to join.
São PauloAges 40–75 - NCT04901273Recruiting
PRP shot vs placebo for knee osteoarthritis in adults 65+
This trial compares an injection made from your own platelets (PRP) to a placebo shot to see if it helps knee osteoarthritis symptoms and function. It is designed for people over 65 with arthritis affecting only one knee.
BolognaAges 65 years+ - NCT05700682Recruiting
MRI-guided artery blockage procedure for long-term joint pain
This study tests whether an MRI scan that looks at blood flow can help target a joint embolization procedure to reduce chronic shoulder, hip, or knee pain. It first uses MRI to find signs of increased blood flow, then may use the findings to guide treatment if you qualify.
Palo Alto, CaliforniaAges 25–80 - NCT06704893RecruitingPhase 3
Amniotic fluid injection for knee arthritis pain
This study tests if an injection made from amniotic fluid can reduce knee pain and improve function in people with moderate knee osteoarthritis. The goal is to give a long-lasting alternative to steroid or gel shots.
Kaohsiung, TaiwanAges 18–80 - NCT06702046Recruiting
Pulsed radiofrequency acupuncture for knee osteoarthritis
This trial tests whether a special type of acupuncture using mild radiofrequency energy can reduce knee pain and improve function in people with knee osteoarthritis. It involves 4 weeks of treatment and a 3-month follow-up to see if the benefits last.
Taipei, StateAges 45–85 - NCT06690710RecruitingPhase 1
Gene therapy injection for knee osteoarthritis
This trial tests a new gene therapy injection for knee osteoarthritis. It aims to see if the treatment is safe and if it can help with knee pain and joint function in people with moderate knee osteoarthritis.
OxfordAges 40 years+ - NCT06681142Recruiting
Pharmacist-physiotherapist team care for early knee osteoarthritis
This study tests a new way to manage early knee osteoarthritis by having a pharmacist and physiotherapist work together. You might get help with pain, stiffness, and movement without needing surgery or strong medications.
Sherwood Park, AlbertaAges 50 years+ - NCT06650631Recruiting
Heat treatment for knee pain from arthritis
This study tests if a heat treatment device can help reduce knee pain caused by arthritis. It involves people with moderate pain who can walk without help and have a recent knee X-ray.
Gravesano, SwitzerlandAges 19–69 - NCT03513731Recruiting
Regenerative fat cell injection for facet joint arthritis pain
This trial tests whether injecting regenerative cells made from your body’s fat can reduce pain from facet joint osteoarthritis in the low back. It focuses on people whose pain has lasted months and did not improve with standard care, after a positive diagnostic injection test.
Deerfield Beach, FloridaAges 18–75 - NCT05278520Recruiting
Study of hip arthritis types during hip replacement surgery
This study looks at differences inside the hip joint and in body cells when people have hip arthritis or rheumatoid arthritis and receive a hip replacement. Researchers hope this can improve understanding and future treatments for these conditions.
Turku, Southwest FinlandAges 18–74 - NCT06600958Recruiting
Study of knee arthritis severity and progression
This study looks at how knee osteoarthritis or other types of knee arthritis progress over time, using blood tests and X-rays. It aims to find markers that could predict whether the disease will get worse, which may help guide treatment decisions.
CréteilAges 18 years+ - NCT06611007RecruitingPhase 1/Phase 2
Lipiodol injections for painful finger arthritis not helped by usual treatments
This trial tests if injecting a special dye (Lipiodol) into the blood vessels of the fingers can safely reduce pain and symptoms in people with hand osteoarthritis that hasn't responded to standard pain relievers.
ÉchirollesAges 40 years+ - NCT06596824Recruiting
Digital training to reduce inflammation after ACL knee surgery
This trial tests a personalized digital training program for people who recently had ACL knee surgery. The goal is to see if correcting movement patterns can lower inflammation and prevent early knee arthritis.
BerlinAges 18–50 - NCT06580561Recruiting
Exercise and insomnia treatment for knee pain
This study combines a gentle exercise program with a treatment for insomnia to see if it helps older adults with knee osteoarthritis feel less pain and sleep better. You will attend group exercise classes and receive sleep coaching.
Ann Arbor, MichiganAges 50 years+ - NCT06576583RecruitingPhase 2
Cartilage graft for kneecap arthritis
This trial tests a new graft made from lab-grown cartilage to treat knee pain under the kneecap. It compares the graft to standard surgery for people with moderate-to-severe kneecap arthritis who haven't improved with other treatments.
ViennaAges 18–70 - NCT06574191Recruiting
Knee osteoarthritis study: pain and health outcomes
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
Sacramento, CaliforniaAges 50 years+ - NCT06549686RecruitingPhase 3
Knee osteoarthritis treatment study with cell therapy
This trial tests a new cell-based treatment (CLS2901C) for knee osteoarthritis. It combines the treatment with a realignment surgery (proximal tibial osteotomy) to help repair cartilage damage and reduce pain.
Ebina, KanagawaAges 20–79
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 592 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.