Clinical trials
Osteochondral Defect clinical trials
Below are recruiting osteochondral defect clinical trials, each written for real people, not researchers. We’re tracking 16 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07161128Enrolling by invitation
Walking Pattern Study After Ankle Cartilage Repair Surgery
This trial will study how walking patterns change after a type of ankle surgery called microfracture with a scaffold, which helps repair a damaged area of bone and cartilage. It may help you if you have that specific defect and are planning this surgery.
Ankara, AnkaraAges 18–65 - NCT03588975RecruitingPhase 3
MACI transplant for knee cartilage defects in ages 10 to 17
This Phase 3 study tests whether a cartilage repair transplant called MACI (a lab-made cartilage-like tissue) can improve symptoms in young people with knee cartilage damage. It compares a surgery approach chosen for each person, aiming to reduce pain and improve knee function.
Palo Alto, CaliforniaAges 10–17 - NCT06462040Recruiting
Dissolving Screws for Loose Knee Cartilage
This study follows patients who have a loose piece of bone and cartilage in their knee and are having it fixed with special screws that dissolve over time. The goal is to see how well the knee heals and works after surgery.
Bologna, BolognaAges 12–35 - NCT04364334Recruiting
Knee care registry for people treated at UMC Utrecht
This study is a “registry,” meaning researchers collect information about your knee care over time. It may help improve understanding and care for people who receive knee treatment at UMC Utrecht.
UtrechtAges Any age - NCT04236492Recruiting
Fresh cartilage graft study for large knee joint damage
This trial studies how well a fresh cartilage and bone graft works to repair large, full-thickness defects in the knee. It also looks at imaging results (pictures of the knee) to see how the repair is healing over time.
Barcelona, CataloniaAges 15–50 - NCT06216756Recruiting
Frozen cartilage transplant for knee cartilage defects
This trial tests a frozen cartilage transplant (called an osteochondral allograft) for people with painful knee cartilage defects. It aims to see if this procedure can help relieve pain and improve knee function.
Phoenix, ArizonaAges 12–60 - NCT04296487Recruiting
ACI treatment for cartilage repair after failed knee care
This trial tests a cartilage-repair procedure called ACI for people whose knee cartilage injury has not improved after at least 6 months of prior treatment. If you qualify, it may help your cartilage heal and reduce symptoms.
Lausanne, Canton of VaudAges 15–50 - NCT05942430Recruiting
Bone-cartilage transplant for ankle joint cartilage damage
This trial studies an “autologous” transplant, meaning using your own bone and cartilage, to treat painful cartilage damage in the ankle (on the talus). It may help people whose ankle cartilage injury is deep, has not improved with non-surgical care, and meets specific side and health requirements.
Guangzhou, GuangdongAges 18–60 - NCT03347877Enrolling by invitation
Autologous bone graft surgery for severe ankle cartilage damage
This trial studies a surgery that uses your own tissue (bone/cartilage part) to repair a specific, advanced ankle cartilage injury (Hepple V) in the talus bone. It may help people with ongoing ankle pain when rest and anti-inflammatory treatments haven’t worked.
Beijing, Beijing MunicipalityAges 18–60 - NCT06915233RecruitingPhase 3
MACI for ankle cartilage defects in adults
This trial tests a treatment called MACI for people with damaged cartilage in their ankle. It uses your own cells to grow new cartilage, which may help reduce pain and improve how you can use your ankle.
Sacramento, CaliforniaAges 17–65 - NCT06915363Recruiting
BioPoly implant for knee cartilage repair
This trial tests a BioPoly implant to repair a small damaged cartilage spot in your knee. If you have a specific type of cartilage injury that didn't get better with other treatments, this implant may help relieve pain and improve function.
Fort Wayne, IndianaAges 30–65 - NCT02503228Enrolling by invitation
Registry study of a preserved bone-cartilage graft
This registry study follows people who get a preserved graft to repair damaged bone and cartilage in a joint. It helps doctors understand how well the graft is preserved and how patients do after surgery over time.
Columbia, MissouriAges 13 years+ - NCT03908931Recruiting
Study of knee cartilage repair results
This study looks at how well certain types of knee cartilage repair work, using clinical check-ins and imaging (scans). You may be able to help researchers understand which method restores knee surface cartilage best.
Le ChesnayAges 18 years+ - NCT03371121Recruiting
AMIC cartilage repair for ankle cartilage damage in adults
This trial studies outcomes after a specific ankle cartilage repair surgery called AMIC. It looks at clinical results and imaging (pictures) after surgery to see how well the treatment works.
MilanAges 18–65 - NCT06311331Enrolling by invitation
Total talus replacement for ankle bone damage
This trial tests a new total talus replacement implant for people with severe talus bone problems like avascular necrosis, non-healing fractures, or large bone defects. It aims to see how well the implant works and how patients recover.
Charlotte, North CarolinaAges 22 years+ - NCT06823089Recruiting
Study of a new hip implant for cartilage repair
This trial tests a new implant called ReNew Hip Implant to repair damaged cartilage in the hip joint. It may be an option if you have hip pain that hasn't improved with other treatments like physical therapy or injections.
St Louis, MissouriAges 14–64
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Common questions
- Are there clinical trials for osteochondral defect?
- Yes. Clin2 currently lists 16 recruiting osteochondral defect studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteochondral defect trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteochondral defect trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.