Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06934681Recruiting
Exercise Program to Help Fight Obesity
This study tests whether a structured exercise program can help people with severe obesity lose weight and improve health. You will be asked to follow a supervised exercise routine to see if it helps you achieve your weight loss goals.
Valencia, ValenciaAges 18–65 - NCT04934228RecruitingPhase 1
Study targeting inflammation in people with obesity and high blood pressure
This Phase 1 study looks at a treatment aimed at reducing “inflammation patterns” that are common in obesity and insulin resistance. If you meet specific health and lab criteria, you may be asked to visit a research lab and provide blood samples to see how the treatment affects your body.
Kansas City, KansasAges 18–79 - NCT06991296Recruiting
Omega-3 supplement study for adults with obesity
This study looks at how omega-3 supplements affect certain fats in the blood of adults with obesity. Researchers want to see if taking these supplements changes these fats in a helpful way.
Kannapolis, North CarolinaAges 45–60 - NCT06989281Enrolling by invitation
Lifestyle medicine study for UAB patients
This study tests a lifestyle program offered in primary care to help patients manage conditions like diabetes, high blood pressure, high cholesterol, or psoriatic arthritis. It aims to see if this approach can improve health and well-being.
Birmingham, AlabamaAges 18–89 - NCT06974851RecruitingPhase 3
Study of HRS9531 for sleep apnea and obesity
This trial tests an injectable medication (HRS9531) to see if it helps people with both obstructive sleep apnea and obesity. It compares the drug to a placebo (no active medicine) to check safety and effectiveness.
Beijing, Beijing MunicipalityAges 18–75 - NCT06966934Recruiting
Nasal airway and oxygen for stomach scope in obesity
This trial tests whether a breathing tube placed in the nose (nasopharyngeal airway) combined with high-flow oxygen can improve safety during painless gastroscopy in people with obesity. It may help you breathe better while sedated.
NanjingAges 18 years+ - NCT03516968RecruitingPhase 3
Monthly vs daily vitamin D for obese children
This study compares taking vitamin D as a monthly dose versus a daily dose in children with low vitamin D levels. It aims to correct the vitamin D deficiency and see which schedule works best and is safe.
BronAges 5–18 - NCT06948058Recruiting
E-cigarettes vs nicotine therapy for quitting smoking in obesity
This study compares e-cigarettes and nicotine replacement therapy (like patches or gum) to help people who are obese quit smoking. Participants use a study product for 8 weeks and track progress with a smartphone app.
Providence, Rhode IslandAges 21 years+ - NCT06946329Enrolling by invitation
Water exercise for knee pain in obese men
This study tests whether a supervised water exercise program (called WATERinMOTION) can reduce knee pain and improve movement in obese men with knee osteoarthritis. It may help if you are looking for a gentle, joint-friendly way to manage your knee pain.
Zahedan, Sistan and BaluchestanAges 45–65 - NCT06937203RecruitingPhase 1/Phase 2
A new obesity drug study for people with or without type 2 diabetes
This early-stage study tests an investigational drug called ARO-ALK7 to see if it helps adults with obesity lose weight. It includes people who have type 2 diabetes as well as those who do not, and requires that you have tried to lose weight with lifestyle changes in the past.
Morayfield, QLCAges 18–65 - NCT06934642RecruitingEarly Phase 1
A study of tirzepatide for fatty liver disease in people with obesity
This trial tests if tirzepatide, a diabetes and weight loss medication, can help improve fatty liver disease in people who are overweight or have obesity. It may offer a new treatment option for managing liver health.
Albuquerque, New MexicoAges 18–75 - NCT06924177Recruiting
Spinal cord injury diet study for wheelchair users
This study tests a special diet program for people with spinal cord injuries who use a wheelchair. It aims to see if the diet can improve health and well-being.
Dallas, TexasAges 18–65 - NCT06916364Enrolling by invitation
Airway rod for intubation in adults with obesity
This trial tests if a special rod helps place a breathing tube more easily in adults with obesity who are having planned surgery. It could make the procedure safer and more comfortable.
Houston, TexasAges 18 years+ - NCT06918821Recruiting
Tiny Steps to Health: Helping Toddlers Play and Eat Well
This study tests a program that helps parents and toddlers ages 1.5 to 3 years learn healthy eating, active play, and physical activity in a group setting. It aims to reduce obesity by making healthy habits fun and easy for the whole family.
Houston, TexasAges 1.5 years–3 years - NCT06916208Recruiting
Capsinoid supplement study for obese teens
This study tests whether a supplement called capsinoid can help activate brown fat in teenagers with obesity. Brown fat is a type of body fat that burns calories, so this could be a new way to help with weight management.
Palavas-les-FlotsAges 11–18 - NCT04220463Recruiting
Hypnosis during noninvasive breathing support for ICU lung illness
This trial tests whether hypnosis can help people in the ICU who need noninvasive breathing support (breathing help without a tube) for breathing flare-ups related to COPD and/or obesity. It aims to make this treatment easier and safer while you are awake.
Rennes, Brittany RegionAges 18 years+ - NCT06901739Recruiting
Synbiotic for mental health in obesity
This trial tests if a synbiotic (a mix of probiotics and prebiotics) can improve mental health in people with obesity. It may help if you have obesity and also struggle with anxiety or depression.
Valencia, ValenciaAges 18–65 - NCT06903923RecruitingPhase 2
Bone health in teens and young adults taking GLP-1 weight loss drugs
This trial looks at how GLP-1 receptor agonist medications (like liraglutide or semaglutide) affect bone health in adolescents and young adults with obesity. It aims to understand if these weight loss drugs have any impact on bone density and metabolism.
Charlottesville, VirginiaAges 12–21 - NCT06907212Enrolling by invitation
Study of fat cell changes in obesity
This study looks at how fat cells change in people with obesity. It involves a small tissue sample (biopsy) and may help us understand more about weight-related health.
CopenhagenAges 18 years+ - NCT06891287RecruitingPhase 1
Testing an oral GLP-1/2 capsule in healthy volunteers
This study tests a new oral capsule that delivers a medicine called PG-102, which is a dual GLP-1/2 agonist (similar to drugs used for diabetes and weight loss). It is for healthy volunteers to see how the body handles the medicine. The study has two parts: one for people with a lower BMI and one for people with a higher BMI (over 30).
Melbourne, VictoriaAges 18–65 - NCT06899178RecruitingPhase 2
Atomoxetine for genetic obesity due to MC4R changes
This trial tests a medicine called atomoxetine (Strattera) to help people with a specific genetic form of obesity lose weight. It may be an option if you have a change in the MC4R gene and have not used certain other medications recently.
New York, New YorkAges 6 years+ - NCT06886126RecruitingPhase 2
Testing HDM1005 injection for weight loss in adults with obesity
This study tests an experimental injection called HDM1005 for adults with obesity who do not have diabetes. The goal is to see if it helps with weight loss when combined with diet and exercise.
NanjingAges 18–65 - NCT06888570Enrolling by invitation
Liver health study for children & young adults with Down syndrome
This study looks at how eating patterns and body composition relate to fatty liver in children and young adults with Trisomy 21 (Down syndrome) or other genetic intellectual disabilities. It may help understand who is at risk and how to prevent liver problems.
Madrid, MadridAges 5–22 - NCT06862479Enrolling by invitation
Comparing a stent to other endoscopic leak treatments
This trial compares a special stent (the Luso-Cor Stent) to other endoscopic procedures to treat leaks or abnormal connections after certain stomach or esophageal surgeries. It aims to find the best way to fix these complications using a scope.
Lisbon, Lisbon DistrictAges 18 years+
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Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.