Clinical trials
Overweight or Obese clinical trials
Below are recruiting overweight or obese clinical trials, each written for real people, not researchers. We’re tracking 1,536 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06782139RecruitingPhase 4
Enavogliflozin for heart health in obesity and diabetes
This trial tests if Enavogliflozin, a medication for diabetes, can improve blood flow in the small vessels of the heart and overall heart function in people with obesity or diabetes. You may join if you have obesity or diabetes and have had a recent heart test.
SeoulAges 20–79 - NCT06789965Recruiting
Comparing two weight loss surgeries for severe obesity
This trial compares two different surgical techniques for people with severe obesity (BMI 40-50) to see which works better. It is for those who are good candidates for bariatric (weight loss) surgery.
Barcelona, BarcelonaAges 18–60 - NCT06790225Recruiting
A study on a gut hormone and bone health
This trial looks at how a natural gut hormone (GIP) affects bone remodeling in healthy people. If you are healthy, you may help us understand how this hormone works on bone cells.
EsbjergAges 18–40 - NCT06790329Recruiting
Weight loss trial using stomach stapling and surface ablation
This trial tests a combined procedure that uses stomach stapling (endoscopic sleeve gastroplasty) plus ablation of the stomach lining to help with weight loss. It is for people with obesity who have not been able to lose weight with diet, exercise, or medication alone.
ShatinAges 18–70 - NCT06800872Recruiting
Vibration therapy for weight loss in teens
This trial tests if whole body vibration can help teenagers with obesity burn more energy while staying in a hospital program. It may offer an extra tool to support weight management.
Oggebbio, VerbaniaAges 13–18 - NCT06800911Recruiting
Metacognitive beliefs in obesity
This study explores how thinking patterns and beliefs about one's own thoughts may be linked to obesity. It aims to understand the role of metacognition in people with severe obesity.
Oggebbio, VerbaniaAges 18–65 - NCT06801496Recruiting
Stomach stent for weight regain after sleeve gastrectomy
This trial is testing a special stomach stent (called a gastric bypass stent) to help people who regained weight after a sleeve gastrectomy. If you've had a sleeve gastrectomy and your BMI is 27.5 or higher, this study might help you lose weight again without another surgery.
BeijingAges 16–65 - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80 - NCT06802861Recruiting
Aspirin metabolism in pregnant women at risk of pre-eclampsia
This study looks at how pregnant women at risk of pre-eclampsia process aspirin and how it affects their metabolism. Researchers will use blood and urine tests, along with body measurements and surveys, to learn more about how aspirin can help prevent pre-eclampsia.
Knoxville, TennesseeAges 18–45 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT06811324RecruitingPhase 2
Tirzepatide for muscle and vessel health in older adults
This study tests if the drug tirzepatide can improve muscle and blood vessel health in older adults with obesity. You may be eligible if you are 50 or older, have a BMI between 30 and 40, and do not have diabetes.
San Antonio, TexasAges 50 years+ - NCT06815978Recruiting
Diagnosing obesity-related muscle loss
This study tests a new tool to diagnose muscle loss in people with obesity. It may help doctors better identify and treat this condition.
Rome, RMAges 18 years+ - NCT06817863RecruitingPhase 1/Phase 2
Mobile app for binge eating and weight loss
This study tests a self-guided mobile app (iPhone or Android) to help adults with binge eating and obesity. It aims to see if the app can reduce binge eating episodes and support weight management.
Philadelphia, PennsylvaniaAges 18–70 - NCT06820099RecruitingPhase 2
A drug for heart failure with obesity
This trial tests an oral drug called HRS-7535 for people with a certain type of heart failure (where the heart pumps normally but doesn't relax properly) and who also have obesity. It aims to see if the drug can improve symptoms and daily function.
Beijing, Beijing MunicipalityAges 18–80 - NCT06822504Recruiting
Sarcopenic obesity in COPD: a prevalence study
This study looks at how common it is to have both COPD (a chronic lung disease) and sarcopenic obesity (loss of muscle with excess body fat). By joining, you'll help doctors understand this condition better and may get a full health check-up.
Roma, RomaAges 40–100 - NCT06833749RecruitingPhase 2
Testing KBP-336 for knee osteoarthritis with obesity
This study tests an experimental medicine called KBP-336 for people with both obesity and knee osteoarthritis who still have significant knee pain despite standard treatments. It aims to see if KBP-336 can reduce pain and improve function.
BrnoAges 45 years+ - NCT06847373Recruiting
Vitamin D for teens with obesity
This study is testing whether vitamin D supplements can help teens with obesity. It is open to participants aged 10 to 18 who live in Mexico City and have obesity based on their BMI.
MéxicoAges 10–18 - NCT06852391RecruitingPhase 4
Weight loss program with or without semaglutide for teens with obesity
This trial studies how the body adapts to weight loss in teens with obesity. You will either get a behavioral lifestyle program alone or with a weight loss medication called semaglutide.
Hamilton, OntarioAges 12–17 - NCT06855251Recruiting
Sensing inner body states in obesity
This trial explores how people with obesity sense signals from their own body (like heartbeat or fullness). Understanding this connection could help develop better treatments.
Piancavallo, VCOAges 18–55 - NCT06862908RecruitingPhase 2
Study of IBI362 for heart failure with obesity
This study tests a new medicine called IBI362 for people with heart failure and obesity. The medicine may help improve symptoms and quality of life. You must have a specific type of heart failure (HFpEF or HFmrEF) and a BMI of 28 or higher.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06885255Recruiting
Fasting and Exercise for Metabolic Syndrome
This study tests whether combining intermittent fasting with exercise can lower inflammation and improve your metabolism and gut health in people with metabolic syndrome.
Erlangen, BavariaAges 18–80 - NCT06886126RecruitingPhase 2
Testing HDM1005 injection for weight loss in adults with obesity
This study tests an experimental injection called HDM1005 for adults with obesity who do not have diabetes. The goal is to see if it helps with weight loss when combined with diet and exercise.
NanjingAges 18–65 - NCT06890169Recruiting
One-stop telehealth program for weight and diabetes
This trial tests a telehealth program that helps people lose weight and manage type 2 diabetes and fatty liver disease at the same time. It's a one-stop remote clinic that combines medical advice, nutrition, and lifestyle support.
SingaporeAges 21–70 - NCT06891287RecruitingPhase 1
Testing an oral GLP-1/2 capsule in healthy volunteers
This study tests a new oral capsule that delivers a medicine called PG-102, which is a dual GLP-1/2 agonist (similar to drugs used for diabetes and weight loss). It is for healthy volunteers to see how the body handles the medicine. The study has two parts: one for people with a lower BMI and one for people with a higher BMI (over 30).
Melbourne, VictoriaAges 18–65
Hear when a new Overweight or Obese trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for overweight or obese?
- Yes. Clin2 currently lists 1,536 recruiting overweight or obese studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obese trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obese trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.