Clinical trials · Cleveland, OH
Overweight or Obesity clinical trials in Cleveland
We’re tracking 18 recruiting overweight or obesity studies with a site in or near Cleveland — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Cleveland
- NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Cleveland, OhioAges 18 years+ - NCT06802081RecruitingPhase 2
Tirzepatide for weight loss in people with atrial fibrillation
This study tests whether tirzepatide, a medication that helps with weight loss and blood sugar control, can improve the heart rhythm condition atrial fibrillation. If you have AFib and are overweight or obese, this trial may be an option for you.
Cleveland, OhioAges 18–80 - NCT07817875RecruitingPhase 3
Tirzepatide for weight loss in children aged 6 to under 12
This study tests a once-weekly medication called tirzepatide to help children aged 6 to under 12 with obesity lose weight. It compares the medication to a placebo (inactive shot) to see if it safely helps with weight loss in this age group.
Cleveland, OhioAges 6–11 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Cleveland, OhioAges 18 years+ - NCT07587437Enrolling by invitation
Magnetic Camera Exam Before Weight-Loss Surgery
This study tests a swallowable magnetic camera to examine your stomach and small intestine before bariatric (weight-loss) surgery. The camera may help doctors plan your surgery and catch any issues beforehand.
Cleveland, OhioAges 18 years+ - NCT06374875RecruitingPhase 4
Does metabolic surgery reduce liver scarring?
This study tests if weight loss surgery can improve liver fibrosis (scarring) in people with obesity and advanced liver disease. It may help those considering surgery to know if their liver health can get better.
Cleveland, OhioAges 18–75 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with excess weight or weight-related health issues
This study tests a once-daily pill called ASC30 to help adults with obesity or overweight who also have conditions like high blood pressure, sleep apnea, or heart disease lose weight. The pill may work by affecting appetite and blood sugar, and the study aims to see how effective and safe it is.
Cleveland, OhioAges 18 years+ - NCT06131281Recruiting
Comparing two endoscopic procedures for weight regain after gastric bypass
This study compares two endoscopic procedures used to help people who have regained weight after gastric bypass surgery. The goal is to see which procedure is more effective at reducing the size of the connection between the stomach and intestine to help with weight loss.
Cleveland, OhioAges 18 years+ - NCT06293703Recruiting
Leg length ratio and weight loss after gastric bypass
This study looks at how the length of different parts of your small intestine affects weight loss after Roux-en-Y gastric bypass surgery. It may help doctors tailor the surgery for better results.
Cleveland, OhioAges 18–70 - NCT06746623Recruiting
Non-endoscopic screening for Barrett's in veterans without reflux
This trial tests a new, non-endoscopic screening method for Barrett's esophagus (a condition that can lead to cancer) in veterans who do not have chronic acid reflux. It aims to find early signs of the condition using a simple swallowable device, potentially avoiding the need for a traditional endoscopy.
Cleveland, OhioAges 40–85 - NCT06425016Recruiting
Robot-assisted vs. traditional sleeve gastrectomy
This study compares two types of weight-loss surgery: one done with the help of a robot and the other done by hand (laparoscopic). Both are types of sleeve gastrectomy, where the stomach is reduced in size. If you qualify for sleeve gastrectomy, this trial may help doctors learn which method works better.
Cleveland, OhioAges 18–70 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Cleveland, OhioAges 6–17 - NCT07268417Enrolling by invitation
Group lifestyle program for obesity in primary care
This study tests if group medical visits with lifestyle coaching can help people with obesity lose weight and improve their health. It takes place at Cleveland Clinic primary care offices.
Cleveland, OhioAges 20–75 - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Beachwood, OhioAges 45–99 - NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
Westlake, OhioAges 18–70 - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Westlake, OhioAges 18–70 - NCT07784270RecruitingPhase 3
Weight loss injection for adults with type 2 diabetes and overweight
This study tests a new injected medicine that may help people with type 2 diabetes and overweight or obesity lose weight. The trial will see how well it works and if it is safe compared to a placebo.
Kent, OhioAges 18 years+
Hear when a new Overweight or Obesity trial opens near Cleveland, OH
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Overweight or Obesity trials in other cities
Where these studies are running near Cleveland
Institutions with a site for the recruiting overweight or obesity studies listed above.
- Cleveland Clinic · 7 studies
- Cleveland Clinic Foundation · 2 studies
- Gastro Intestinal Research Institute of Northern Ohio · 2 studies
- AURORA-1 Clinical Site
- AURORA-2 Clinical Site
- Cleveland Clinic Main Campus
- Louis Stokes Clvlnd VA Med Ctr
- Research Site
What taking part in a overweight or obesity study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting overweight or obesity studies in Ohio.
Common questions
- Are there overweight or obesity clinical trials near Cleveland?
- Yes. We're currently tracking 18 recruiting overweight or obesity studies with a site near Cleveland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a overweight or obesity study near Cleveland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Cleveland to take part?
- Not necessarily. These studies have a site near Cleveland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New overweight or obesity studies open near Cleveland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.