Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05351476Recruiting
Exercise program for metabolism in postmenopausal women
This trial studies whether a structured exercise program can improve how your body uses fat. It is designed for postmenopausal women with higher weight and prediabetes who are not currently exercising much.
Tallahassee, FloridaAges 50–75 - NCT05305313RecruitingPhase 4
Testing a new propofol dosing method for higher BMI surgeries
This trial studies whether adjusting how propofol (an anesthesia medicine) is dosed based on total body weight improves anesthesia delivery during longer surgeries. It mainly targets people with a higher body mass index having surgery that lasts over an hour.
New Delhi, National Capital Territory of DelhiAges 18–65 - NCT05289310Recruiting
Home low-oxygen nights to study weight and health
This study looks at whether spending 8 hours each night in a low-oxygen tent for 8 weeks affects weight and related health in people with obesity. It also checks safety by monitoring oxygen levels and screening for breathing and heart-related conditions.
Baton Rouge, LouisianaAges 22–65 - NCT05279729Recruiting
Mobile app coaching for people with diabetes
This study tests whether using a smartphone app can help people with type 2 diabetes manage their health. It focuses especially on low-income Hispanic/Latinx adults who regularly check blood sugar.
San Diego, CaliforniaAges 18–64 - NCT05199454Recruiting
Study how “fat-like” particles affect blood vessel function
This study looks at whether tiny fat-based particles (“adiposomes”) can affect how well your blood vessels work, especially in people with diabetes and higher body weight. You may be asked to do moderate exercise and other study procedures after passing safety checks.
Chicago, IllinoisAges 18–50 - NCT05216042Recruiting
Study of genetics and heart/metabolic health in adults
This study looks at how genetic markers (DNA) relate to heart health and “metabolic” health (how your body manages sugar and fat). You may be asked to provide genetic samples and follow study health checks and protocols to help researchers understand who is at higher risk.
Birmingham, AlabamaAges 18 years+ - NCT05166447Enrolling by invitation
Check-in study for people from the Inter99 health survey
This study is a long-term follow-up of people who took part in the Inter99 baseline exam. It involves a 3-hour check-in, and it can help researchers learn how people’s health changes over time.
Glostrup MunicipalityAges 50–82 - NCT05147909Recruiting
Testing too much phosphate on exercise and belly fat
This trial studies whether eating extra phosphate changes how well you can exercise and how much visceral (deep belly) fat you have. Because it is a crossover study, you would likely try different phosphate amounts on separate occasions.
Dallas, TexasAges 18–80 - NCT05173714RecruitingPhase 2
Sit Less and Move More program for people with CKD
This Phase 2 study tests a program to help people with chronic kidney disease (CKD) sit less and move more, plus a medication (semaglutide) for those who qualify. It may help improve health and day-to-day activity while monitoring safety closely.
Stanford, CaliforniaAges 20 years+ - NCT04930029Recruiting
Long-term follow-up after gastric bypass with an omega limb
This study looks at long-term side effects years after gastric bypass surgery done in a specific way. If you had this type of surgery and agree to an endoscopy with small tissue samples at 10 years, you may help doctors understand longer-term outcomes.
LilleAges 18 years+ - NCT05082519RecruitingPhase 2
Calorie restriction and exercise to improve leukemia treatment in young patients
This study tests whether a special diet (calorie restriction) and increased physical activity can make chemotherapy work better for young people with B-ALL. Participants will follow a monitored diet and exercise plan during their first month of treatment.
Los Angeles, CaliforniaAges 7–25 - NCT05067231Recruiting
UAB heart research biobank for adults 18 and older
This study builds a heart-focused research database by enrolling adults who are willing to provide information and/or samples for future cardiovascular research. It may help researchers study heart disease and develop better treatments over time.
Birmingham, AlabamaAges 18 years+ - NCT05071898RecruitingPhase 1
Studying how genetics affect response to GLP-1 weight-loss drugs
This early-stage study looks at how genetic factors may change how people respond to a GLP-1 medicine (semaglutide). The goal is to learn who may benefit most and why, so future treatments can be better matched.
Lancaster, PennsylvaniaAges 18–89 - NCT05051436RecruitingPhase 4
Testing mirabegron and tadalafil to improve sugar control
This study looks at whether mirabegron and tadalafil can improve blood sugar control in people with prediabetes. It may help determine if these medicines can slow the move from prediabetes toward diabetes.
Lexington, KentuckyAges 35–65 - NCT04913064Recruiting
White button mushroom supplement for inflammation in high-risk breast cancer
This trial tests whether a white button mushroom powder supplement can lower inflammation in postmenopausal women who have a high risk of breast cancer. If it helps, it could improve early prevention strategies for people at higher risk.
Duarte, CaliforniaAges 21 years+ - NCT04997473Recruiting
Mobile app weight-loss program for young transplant patients
This trial tests whether a phone app can help young people who previously had a stem cell transplant lose weight. It’s designed for people who are at least 100 days out from transplant and who meet weight criteria.
Los Angeles, CaliforniaAges 13–30 - NCT04971720RecruitingPhase 2/Phase 3
Personalized blood pressure timing therapy for some adults
This trial tests whether timing blood pressure medications (based on your natural daily body rhythms) can improve blood pressure control. It’s designed for adults with moderately high blood pressure and focuses on who may benefit from a more precise schedule.
Birmingham, AlabamaAges 18 years+ - NCT04894838Recruiting
Testing a bypass revision surgery for weight regain
This study looks at whether a specific stomach bypass revision (a “distal gastric bypass”) can improve outcomes after Roux-en-Y gastric bypass when weight loss was not enough or weight was regained. You may be considered if you meet weight-loss goals criteria and can join follow-up and possibly surgery.
Arnhem, GelderlandAges 18–65 - NCT04812314Recruiting
Study how exercise changes body fat and metabolism
This study looks at how starting exercise changes the structure and function of body fat. It may help you understand how exercise affects things like cholesterol and blood sugar, even if you’re not currently exercising regularly.
Ann Arbor, MichiganAges 18–40 - NCT04841057Enrolling by invitation
Study of blood and stool changes after weight-loss surgery
This study looks at how your body’s metabolism changes after a specific weight-loss surgery (gastric bypass). It may help researchers better understand what to expect and how to tailor care, while requiring blood draws and stool samples before and after surgery.
Columbia, MissouriAges 18–80 - NCT04851470Recruiting
Dental gum check in adults with obesity
This study looks at gum health in adults with obesity. It may help researchers understand how weight and related health factors affect periodontal (gum) status and what to monitor in bariatric care populations.
LondonAges 18 years+ - NCT04708535Enrolling by invitation
Study how fat changes affect insulin resistance after bariatric surgery
This study looks at how your body’s fat under the skin and inside the abdomen may affect “insulin resistance,” a common problem linked with blood sugar control. It’s for people who are scheduled for bariatric (weight-loss) surgery, to learn more before and after surgery.
Stanford, CaliforniaAges 30–65 - NCT04678752Enrolling by invitation
Weight management program through primary care visits
This study tests a practical weight-management approach delivered in regular primary care clinics. You may be offered support to help with weight if you’re an adult with a higher-than-normal BMI.
Arvada, ColoradoAges 18–89 - NCT04611087Recruiting
Weight-loss program participants: self-monitoring focus group
This trial is looking to learn from people who finished a specific weight-loss program recently and ask them to share their experiences. The goal is to improve how weight-loss support and tracking work for participants.
Houston, TexasAges Any age
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,472 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.