Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,533 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07193927RecruitingPhase 2
Testing a probiotic mix for fatty liver disease (MASLD)
This trial tests whether a probiotic mixture can improve liver health in people with moderate fatty liver disease (MASLD). It looks at how the probiotic affects liver fat, inflammation, and metabolism.
Girona, GironaAges 18–75 - NCT07207772Recruiting
Electric lung imaging vs. standard breathing support in weight-loss surgery
This study compares two ways of setting the breathing machine during weight-loss surgery: one guided by electrical impedance tomography (EIT) and the other by standard care. The goal is to see which one helps your lungs work better during and after surgery.
Jinan, ShandongAges 18–65 - NCT07209202Recruiting
Study on Fructose Handling in Obesity
This study looks at how the body handles fructose (a natural sugar) in people with different weights. It may help explain why some people process sugars differently.
Vallejo, CaliforniaAges 20–55 - NCT07211217Recruiting
Time-restricted eating for bipolar depression
This study tests if eating only during a specific daily window can help with weight loss and mood in people with bipolar disorder who are currently depressed and overweight.
Boston, MassachusettsAges 18–65 - NCT07215533Recruiting
Exercise trials for teens and young adults at risk for diabetes
This study compares two types of exercise—high-intensity interval training (HIIT) and time-restricted eating (TRE)—to help lower the risk of developing type 2 diabetes in teens and young adults who are overweight or have obesity.
Syracuse, New YorkAges 14–30 - NCT07226947Recruiting
Exercise to prevent muscle loss with GLP-1 medication
This study looks at whether exercise can help prevent muscle loss in people taking GLP-1 medications (like Wegovy, Ozempic, or Mounjaro) for weight loss. It may help you keep your muscles strong while you lose weight.
Boston, MassachusettsAges 18–99 - NCT07238556Recruiting
Digital tool for doctors to prescribe exercise
This trial tests a digital tool that helps doctors create personalized exercise plans for patients with heart disease risk factors. It aims to help you become more active in a safe, supported way.
Farmington, ConnecticutAges 18–64 - NCT05371496Enrolling by invitationPhase 4
Semaglutide for heart failure patients with preserved pumping function
This Phase 2 trial studies whether semaglutide can improve heart function and related body/heart “metabolic” effects in people with heart failure with preserved ejection fraction. It may help you by improving the heart pressures that build up when you’re active and may reduce harmful strain on the body.
Rochester, MinnesotaAges 18 years+ - NCT07268508Recruiting
Study of a gut-healthy diet after weight-loss surgery
This study tests how a special diet after weight-loss surgery affects gut bacteria, eating habits, and sense of taste and smell. Researchers want to see if this diet can improve long-term results.
LyonAges 25–65 - NCT07270068Recruiting
Diabetes remission through lifestyle change for Malaysian patients
This study tests whether a lifestyle program can help Malaysian adults with recently diagnosed type 2 diabetes and overweight or obesity achieve remission of their diabetes. If you qualify, you’ll get support to change your diet and activity habits.
Seremban, Negeri SembilamAges 18–70 - NCT07272460Recruiting
Time-restricted eating for type 2 diabetes and weight health
This study is testing whether eating all your meals within a set window of time each day (time-restricted eating) can help improve blood sugar control and overall health in people with type 2 diabetes and excess weight.
Toronto, OntarioAges 18–75 - NCT07282340RecruitingPhase 2
Phentermine for weight loss in teens
This study tests a medicine called phentermine to help teens ages 12 to 17 with obesity lose weight. It will check if the medicine is safe and works well for teenagers.
Albuquerque, New MexicoAges 12–17 - NCT07289555Recruiting
Customized SADI-S surgery after sleeve gastrectomy
This trial tests a new, customized version of a weight-loss surgery called SADI-S for people who had a sleeve gastrectomy before but need more help losing weight or keeping it off. The goal is to see how safe and effective this tailored surgery is.
Cairo, Greater CairoAges 18–65 - NCT07294950RecruitingPhase 3
What happens when you stop semaglutide after weight loss
This study looks at what happens to your body and weight when you stop taking semaglutide (Wegovy/Ozempic) after losing at least 10% of your starting weight. The goal is to understand how your metabolism and heart health change once the medication is paused.
Toronto, OntarioAges 18–75 - NCT07296861Recruiting
Home program for healthy growth in children with Down syndrome
This study tests a family-based program you can do at home to help your young child with Down syndrome develop healthy habits. It aims to support your child's growth and well-being through fun activities and guidance.
Chapel Hill, North CarolinaAges Any age - NCT07305168Recruiting
Breathing after tonsil surgery in children with sleep apnea
This study looks at breathing problems that can happen after tonsil or adenoid surgery in children who have sleep apnea. Researchers want to learn more so they can make surgery safer for kids.
Edegem, AntwerpAges 1–18 - NCT07309094Recruiting
Effects of a diabetes drug on fat tissue in kidney disease
This trial tests whether a GLP-1 receptor agonist (a type of diabetes medication) can improve fat tissue health in people with chronic kidney disease who also have type 2 diabetes, cardiovascular disease, or obesity. It may help protect your kidneys and overall health.
Valencia, ValenciaAges 18–90 - NCT07314996Recruiting
Laparoscopic vs. open surgery for colon cancer with belly fat
This trial compares laparoscopy (minimally invasive) and open surgery for treating colon cancer in people with extra belly fat around internal organs (visceral obesity). The goal is to see which approach gives better recovery and outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07318727Recruiting
Diet study for weight loss in overweight endometrial cancer patients
This study tests if specific diet changes can help overweight women with endometrial cancer or atypical hyperplasia lose weight while undergoing fertility-sparing treatment.
BeijingAges 18–40 - NCT07326865Recruiting
Sugar metabolism study in obese patients with and without MASLD
This study looks at how the liver responds to sugar given through a vein in obese patients with and without a fatty liver condition called MASLD. It may help doctors understand why some people develop liver problems from sugar and fat.
Amsterdam, North HollandAges 35–65 - NCT07331389RecruitingPhase 1
How HDM1002 interacts with common drugs and diabetes medications
This study tests how a new drug called HDM1002 interacts with common diabetes medications (metformin, empagliflozin) and other drugs like warfarin and valsartan. If you are a generally healthy adult (age 18-45) with a higher BMI, this trial helps ensure the new drug is safe when taken with other medicines.
HefeiAges 18–45 - NCT07335731Recruiting
Safety and effectiveness of a new robot for weight-loss surgery
This trial tests a new robot-assisted device for weight-loss surgery in people with obesity. It aims to see if the device is safe and works well for metabolic conditions.
BeijingAges 18–65 - NCT07336862RecruitingPhase 1/Phase 2
Weight loss surgery plus GLP-1 drug for obesity and diabetes
This trial tests whether adding a GLP-1 receptor agonist (a medication that helps control blood sugar and appetite) after weight loss surgery improves outcomes for people with severe obesity and related health problems like type 2 diabetes.
BeijingAges 18–60 - NCT07339423RecruitingPhase 3
A study of a new medicine for weight loss
This study tests a new medicine to see how well it helps people with excess body weight lose weight. It may be an option if you have tried to lose weight through dieting before but haven't had lasting success.
Miramar, FloridaAges 18 years+
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,533 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.