Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,527 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07503210RecruitingPhase 3
Study of a new medicine to maintain weight loss
This study tests an investigational medicine to help people who have lost weight keep it off. It's for adults without diabetes who haven't used similar weight-loss drugs before.
Anniston, AlabamaAges 18 years+ - NCT07517042Recruiting
Lifestyle changes and mazdutide injection for weight loss
This trial tests whether combining lifestyle changes (diet and exercise) with a medication called mazdutide can help adults with obesity lose weight and keep it off. Mazdutide is an injectable medication that may help reduce appetite and support weight management over 2 years.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07527195RecruitingPhase 1
Study of CagriSema on Muscle Health in Adults with Obesity
This study tests a new medication called CagriSema to understand how it affects muscle health while helping people lose weight. You'll be in the trial for about a year, and researchers will monitor your muscle function and body composition.
Aarhus NAges 50–70 - NCT07529119Recruiting
Mango and Chia Drink Effects on Gut Health in Children
This study tests whether a special drink made with mango and chia seeds can improve gut bacteria health in children who are overweight or obese. Researchers want to see if this drink might help with weight and digestion.
Coronel OviedoAges 8–16 - NCT07530718Recruiting
How Weight-Loss Surgery Affects Body Composition in MS Patients
This study follows people with multiple sclerosis (MS) who are having weight-loss surgery to understand how their body composition—the balance of muscle, fat, and bone—changes after surgery. The research may help doctors better support MS patients through weight-loss surgery.
Baton Rouge, LouisianaAges 18 years+ - NCT07542873Recruiting
How Low Oxygen Affects Iron Absorption in People with Obesity
This study tests whether sleeping in a special tent that lowers oxygen levels for 8 weeks affects how your body absorbs iron. Researchers want to understand if low-oxygen conditions change iron levels in people with obesity.
Baton Rouge, LouisianaAges 22–65 - NCT07543666Recruiting
Exercise and inflammation markers in healthy young adults
This study looks at how starting a structured exercise program affects inflammation in the body. Researchers want to understand the link between physical activity and inflammation markers in healthy young adults.
München, BavariaAges 18–45 - NCT07553936Recruiting
Alternative Proteins in Mediterranean Food Supply Chains
This study tests new plant-based and alternative protein foods (like those from legumes, insects, and algae) to see if they're safe, healthy, and practical for everyday use. You'll help researchers understand how these sustainable protein options can work in Mediterranean diets.
Bologna, BOAges 18–65 - NCT07565051Recruiting
Predicting weight loss after gastric bypass surgery
This study looks at whether measuring muscle mass before gastric bypass surgery can predict how much weight you'll lose afterward. Understanding this connection may help doctors better prepare patients for surgery and set realistic goals.
Geneva, Canton of GenevaAges Any age - NCT07568938Recruiting
Anesthesia types and stress response in weight-loss surgery
This study compares two anesthesia methods—inhaled gas (desflurane) versus IV medication (TIVA)—during weight-loss surgery to see how each affects your body's stress response and recovery. The goal is to understand which approach may be safer and more comfortable for patients having bariatric surgery.
AthensAges 18–65 - NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT07585487Recruiting
How medications work in children of different weights during surgery
This study measures how two common medications—paracetamol (pain reliever) and cefazolin (antibiotic)—move through the body differently in children who are normal weight versus overweight. Researchers will take small blood samples during routine surgery to understand the best doses for each child.
GhentAges 2–15 - NCT07588438RecruitingPhase 4
Tirzepatide effectiveness and safety for diabetes and weight loss in Paraguay
This study tests how well and safely tirzepatide (a new injectable medication) works in real-world conditions for people with type 2 diabetes or obesity in Paraguay. The medication helps lower blood sugar and reduce weight.
AsunciónAges 18–70 - NCT07589322Recruiting
How GLP-1 drugs reshape fat and metabolism
This study compares how a GLP-1 medication (a drug that helps control blood sugar and weight) changes the way your body stores and uses fat. Researchers will use imaging scans to see these changes over time in people with metabolic syndrome—a cluster of health conditions including high blood pressure, high cholesterol, and excess weight.
TaipeiAges 20–65 - NCT07589647Recruiting
Brain Stimulation for Bipolar Disorder and Weight Management
This study tests whether a small electrical stimulation device targeting a specific brain region (the suprachiasmatic nucleus) can help improve metabolic health and weight in people with stable bipolar disorder who also have obesity. The goal is to see if this approach is safe and effective.
Hangzhou, ZhejiangAges 18–45 - NCT07600411Recruiting
Weight-loss surgery and mood: comparing two surgical approaches
This study follows patients undergoing one of two common weight-loss surgeries (sleeve gastrectomy or gastric bypass) to see how each affects binge eating, depression, and anxiety. Researchers want to understand which surgery may help improve both weight and mental health outcomes.
Cairo, Al-Manial CairoAges 18–60 - NCT07604610Recruiting
Heart Fat and Metabolic Health in Older Adults
This study looks at fat tissue around the heart and how it relates to metabolic health (blood sugar, cholesterol, weight) in people aged 50–70. Researchers will use ultrasound imaging to measure this fat and understand its connection to heart disease risk.
MoscowAges 50–70 - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT07662356Recruiting
NAFLD study in Chinese patients having obesity surgery
This study follows Chinese patients who are having obesity surgery to understand how nonalcoholic fatty liver disease (NAFLD) changes over time and to find markers that might predict its course. It could help doctors better treat liver problems in people with obesity.
Hong Kong, New TerritoriesAges 18 years+ - NCT07663942Recruiting
Reducing sitting time and boosting fitness before and after weight-loss surgery
This study tests a program to help women reduce sitting time and increase physical fitness before and after bariatric surgery (like gastric bypass or sleeve gastrectomy). It aims to improve long-term health outcomes.
Santa Maria da FeiraAges 18 years+ - NCT07666074Recruiting
AI for predicting difficult airway in weight-loss surgery
This trial uses artificial intelligence (AI) to predict whether it will be difficult to place a breathing tube during weight-loss surgery. The goal is to help doctors plan safer anesthesia for patients with a high BMI.
Elâzığ, ElâzığAges 18–65 - NCT07587437Enrolling by invitation
Magnetic Camera Exam Before Weight-Loss Surgery
This study tests a swallowable magnetic camera to examine your stomach and small intestine before bariatric (weight-loss) surgery. The camera may help doctors plan your surgery and catch any issues beforehand.
Cleveland, OhioAges 18 years+ - NCT07551960Enrolling by invitation
Testing a Health Risk Prevention Platform for Adults
This study tests a digital platform called STELA that helps adults reduce their risk of heart disease and stroke by identifying and managing modifiable health factors like diet, exercise, and stress. You'll complete health assessments online to see if this preventive approach works.
Třinec, Moravian-Silesian RegionAges 18–80 - NCT07528963Enrolling by invitation
Enhanced Cancer Survivorship Care in Rural Kansas Clinics
This study tests a new model of cancer care designed for rural areas, focusing on helping breast, prostate, lung, and colorectal cancer survivors manage their health after treatment. The study works through primary care clinics to make survivorship care more accessible and effective.
Kansas City, KansasAges 18–75
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Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,527 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.