Clinical trials
Overweight clinical trials
Below are recruiting overweight clinical trials, each written for real people, not researchers. We’re tracking 530 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07150975RecruitingPhase 3
Study comparing new weekly injection vs. Wegovy for weight loss
This trial tests a new weekly injection called GZR18 against the existing drug Wegovy for weight loss in adults who are overweight or obese. It aims to see which is more effective and safe for helping people lose weight and improve related health conditions.
BeijingAges 18 years+ - NCT07140952Recruiting
Heart-healthy diet and exercise for stroke survivors
This study tests a heart-healthy diet and exercise plan for stroke survivors to improve health and fitness. It is done virtually to make it easy to join from home.
Florence, South CarolinaAges 45–80 - NCT07136714RecruitingPhase 4
Semaglutide for depression in people with overweight
This study tests whether a weekly injection of semaglutide (a medication used for weight loss and diabetes) can help reduce symptoms of depression in people who have major depressive disorder and are overweight or obese.
Hillerød, DenmarkAges 18–65 - NCT07143552Recruiting
Bone health in kids with fractures from minor falls
This study looks at bone health in children aged 3 to 15 who break a bone after a minor fall (like tripping). It compares them to children who don't break a bone, to see if things like body weight, sun exposure, or other factors affect bone strength.
Brixen, BolzanoAges 3–15 - NCT07128888RecruitingPhase 1
GZR18 injection effects on stomach emptying and drug interactions
This trial tests how a new injectable drug, GZR18, affects how fast your stomach empties and how it interacts with other medicines. It is for obese Chinese adults who want to join a research study.
BeijingAges 18–50 - NCT07134335RecruitingPhase 2
Study of UBT251 injection for chronic kidney disease
This study tests an investigational injection called UBT251 for people with chronic kidney disease who are overweight. It aims to see if it can reduce protein in the urine and help protect kidney function.
BeijingAges 18–75 - NCT07129434Recruiting
Helping mothers with PCOS and their babies bond better
This study tests whether a special program can help mothers with PCOS and obesity improve their emotional connection with their babies. It may offer tools for healthier emotional growth for both mom and child.
OuluAges Any age - NCT07123779RecruitingPhase 1/Phase 2
Study of a new drug for heart failure with pulmonary hypertension
This study tests an investigational drug (HS235) for people who have both heart failure with preserved ejection fraction and a type of pulmonary hypertension that can happen with it. The goal is to see if the drug can improve symptoms and quality of life.
Kansas City, MissouriAges 18 years+ - NCT07118540Recruiting
Weight-loss surgery follow-up after 5 years
This trial is checking how well patients are cared for after weight-loss surgery, focusing on those who stopped coming to check-ups 5 years after their operation. If you were part of the OBESEPI study and haven't been seen recently, this research wants to understand your experience.
Nancy, LorraineAges 18–65 - NCT07114419RecruitingPhase 2
New weekly injection for weight loss in overweight or obesity
This study tests a new weekly injection, efsubaglutide alfa (a GLP-1 drug), for helping people with overweight or obesity lose weight. It is for people who have not been able to lose weight with diet and exercise alone and do not have other serious health conditions.
BrookvaleAges 18–75 - NCT07112521Recruiting
Brain stimulation for thinking problems after breast cancer
This study tests whether a gentle brain stimulation technique called tDCS can help with thinking and memory problems after breast cancer treatment. It compares women with and without obesity to see if the treatment works differently.
Helsinki, UusimaaAges 18 years+ - NCT06937060RecruitingPhase 3
Semaglutide for psoriasis and obesity
This trial tests if semaglutide, a medicine used for diabetes and weight loss, can help people with both psoriasis and obesity. You may qualify if you have moderate to severe psoriasis, a high body weight, and are of Chinese descent.
Hong KongAges 18–75 - NCT07097506RecruitingPhase 2
Ketone drink for liver fat and health
This study tests whether a daily ketone ester drink can reduce liver fat and improve metabolism in people with excess liver fat. You may join if you are 18–40, have overweight or obesity, and your liver has extra fat.
St Louis, MissouriAges 18–40 - NCT07090005Recruiting
Endoscopic weight loss: comparing EndoZip and Apollo ESG
This study compares two different endoscopic procedures (EndoZip and Apollo ESG) to help obese patients lose weight. Both are done through the mouth without cutting the skin, and the goal is to see which works better and is safer.
Los Angeles, CaliforniaAges 21–65 - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07095543Recruiting
Plant-based weight loss through online program
This study tests an online weight loss program based on a plant-based diet. You may be able to join if you live in the U.S., are overweight, can travel to Washington DC for a body scan, and are not using weight loss medications.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT06897241Recruiting
How different starches affect your metabolism
This study tests how your body responds to different types of starch (quick, slow, and resistant). You will follow special diet plans and use monitoring devices to understand your personal metabolic reactions.
Gothenburg, Västra Götaland CountyAges 30–75 - NCT07075952Recruiting
Training app for food impulse control
This study tests a mobile app that helps you learn to control your impulses around food. It's for people with obesity, binge eating disorder, or bulimia nervosa.
Padova, PadovaAges 16 years+ - NCT07082062Recruiting
GLP-1 formula for glucose control
This trial tests whether a special GLP-1 formula can help regulate blood sugar and increase GLP-1 levels in people with higher body fat. It may offer a new way to support metabolic health.
TaichungAges 18–50 - NCT07081152Recruiting
Iron absorption and losses in young South African women
This study looks at how well young South African women absorb iron and how much iron they lose, comparing women with healthy weight to women with overweight or obesity. It aims to learn if body weight affects iron balance.
Potchefstroom, North WestAges 18–35 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT07075341Recruiting
Healthy living beyond weight study
This study tests whether a program focused on healthy eating and activity can help people manage their weight or maintain a healthy weight after treatment. It may be right for you if you are an adult concerned about your weight or health.
Dallas, TexasAges 18 years+ - NCT07065643Recruiting
Calorie restriction study for healthy overweight adults
This study looks at how sex hormones affect the benefits of a low-calorie diet in men and women of different ages. If you are a healthy overweight adult, the study may help understand how hormones and age influence weight loss results.
AberdeenAges 18–65
Hear when a new Overweight trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for overweight?
- Yes. Clin2 currently lists 530 recruiting overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.