Clinical trials
Oxygenation clinical trials
Below are recruiting oxygenation clinical trials, each written for real people, not researchers. We’re tracking 383 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05289310Recruiting
Home low-oxygen nights to study weight and health
This study looks at whether spending 8 hours each night in a low-oxygen tent for 8 weeks affects weight and related health in people with obesity. It also checks safety by monitoring oxygen levels and screening for breathing and heart-related conditions.
Baton Rouge, LouisianaAges 22–65 - NCT05223192Recruiting
Testing music to improve breathing and brain oxygen in preemies
This study looks at whether planned music sessions can help preterm babies breathe more steadily and improve oxygen reaching the brain. It may help staff learn how to use music therapy safely for newborns in the NICU.
New York, New YorkAges 6 months–9 months - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT02851758Recruiting
Autologous mitochondria treatment for critically ill heart children on ECMO
This trial looks at giving a child their own mitochondria to help protect the heart from injury caused by reduced blood flow. It is for children with serious heart problems who are on a heart-lung machine and may have signs of ischemia (reduced blood flow damage).
Boston, MassachusettsAges Up to 17 years - NCT04855396Recruiting
Study of blood markers during hyperbaric oxygen brain injury care
This trial looks at blood “biomarkers,” or lab measurements, while people receive hyperbaric oxygen treatment for brain injury as part of the main HOBIT study. It may help researchers understand who benefits and why by improving how treatment responses are tracked.
San Diego, CaliforniaAges 16–65 - NCT03593408Recruiting
Study drug levels in children on ECMO
This study measures how sedating and pain medicines move through the body in children who are supported by ECMO (a heart-lung machine). It may help doctors choose safer and more effective dosing for sedation and pain control during ECMO.
Boston, MassachusettsAges birth–17 years - NCT04709432Recruiting
Study of ECMO care for children in China
This study looks at children (ages 1 day to 18 years) in mainland China who were treated with ECMO during the past 10 years. It aims to understand how ECMO was used and how care outcomes may have differed for children.
Shanghai, Shanghai MunicipalityAges 1 day–18 years - NCT04471129Recruiting
Noninvasive breathing support after heart surgery to protect heart function
This study tests whether two noninvasive breathing/oxygen treatments after cardiac surgery help improve heart function. It may benefit people with weak pumping function who are recovering in the hospital and can safely use these devices.
RouenAges 18 years+ - NCT04440280RecruitingPhase 2
NAC drops to improve cornea disease during cataract surgery
This Phase 2 study tests whether eye drops containing a medicine called N-acetylcysteine (NAC) can reduce damaging “reactive oxygen” in people with advanced Fuchs’ endothelial corneal dystrophy (FECD). It involves people who need a special cornea transplant (DMEK) at the same time as cataract surgery, aiming to improve cornea healing and vision.
Boston, MassachusettsAges 21 years+ - NCT04441151Recruiting
Pulmonary rehab for adults on high-flow oxygen therapy
This trial tests whether pulmonary rehabilitation (supervised breathing and activity training) improves outcomes for adults who need high-flow oxygen. You may be eligible if your breathing and heart/vital signs are stable and your oxygen level is above a certain threshold.
Beijing, Beijing MunicipalityAges 18–100 - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT04273607RecruitingPhase 2/Phase 3
Test an ECMO approach without blood thinners for lung failure
This trial studies whether people on a breathing machine called VV-ECMO can be managed without routine blood thinners, to reduce bleeding risk. It is meant for adults with severe lung failure (ARDS) and checks that it is safe for you to avoid anticoagulation.
Toronto, OntarioAges 18 years+ - NCT04198792Recruiting
Finding outcomes after ECMO for heart-related emergencies
This study looks at what helps determine survival and better brain function after people are treated with ECMO, a heart-lung support machine. It may help doctors understand who is most likely to do well after this kind of emergency treatment.
GothenburgAges 16 years+ - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT04118387RecruitingPhase 4
Study of how to treat central sleep apnea in Veterans
This Phase 4 study looks at what’s going on in the body during central sleep apnea and uses that information to guide treatment. If you have central sleep apnea, this could help confirm or improve how treatment is chosen for you.
Detroit, MichiganAges 18 years+ - NCT04086329RecruitingPhase 1
Testing an oxygen sensor during exercise in muscle disease
This early (Phase 1) study checks whether a tiny oxygen-sensing device works reliably while people with mitochondrial muscle disease (and some healthy volunteers) ride a stationary bike. The goal is to see if the sensor can measure oxygen use during exercise and help future monitoring or research.
Philadelphia, PennsylvaniaAges 18–65 - NCT03948048Recruiting
ECMO timing study for children with hard-to-treat septic shock
This trial looks at whether and when a heart-lung machine called ECMO should be used in children whose septic shock is not responding to standard treatment. It may help doctors choose the best timing to improve survival and recovery in the PICU.
ShanghaiAges 4 weeks–18 years - NCT03649880RecruitingPhase 2
Imaging brain tumors with FMISO in adults
This trial tests whether a new imaging agent called FMISO can help see areas of low oxygen in brain tumors. It may help doctors better target treatment for gliomas.
Portland, OregonAges 18 years+ - NCT03054792Enrolling by invitationPhase 1
MRI test to map low-oxygen areas in childhood sarcomas
This Phase 1 study uses special MRI scans to look at “low-oxygen” parts of a childhood sarcoma. It aims to help doctors better understand the tumor before standard treatment that may include chemotherapy and sometimes radiation.
Toronto, OntarioAges 6–18 - NCT02703207Recruiting
Sleep apnea and COPD effects in older veterans
This study looks at how sleep apnea affects thinking skills and overall health in older veterans who also have COPD. It may help researchers understand what changes to target to improve daytime functioning and wellbeing.
Detroit, MichiganAges 60–89 - NCT02922894RecruitingPhase 4
Testing sleep apnea care in people with spinal cord injury
This study looks at treatment for sleep apnea (breathing pauses during sleep) in adults with a spinal cord injury. If you qualify, the trial team may help manage sleep-related breathing problems and track how well the treatment works.
Detroit, MichiganAges 18–89 - NCT02464696Recruiting
Noninvasive breathing support to avoid tube breathing in cancer
This trial studies a mask-based breathing treatment (noninvasive ventilation) for people with cancer and serious breathing trouble, to see if it can prevent the need for intubation (putting a breathing tube in). If you qualify, the goal is to help you breathe better without invasive airway support when possible.
Houston, TexasAges 18 years+ - NCT02323945Recruiting
Low-oxygen breathing to improve leg movement after spinal injury
This study tests whether breathing brief, mild low-oxygen air (under supervision) can improve leg mobility in people with a certain type of spinal cord injury. It may help with regaining movement, especially if you can already move your legs voluntarily but still have mobility limits.
Cambridge, MassachusettsAges 18–75
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Common questions
- Are there clinical trials for oxygenation?
- Yes. Clin2 currently lists 383 recruiting oxygenation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oxygenation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oxygenation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.