Clinical trials
Pain Threshold clinical trials
Below are recruiting pain threshold clinical trials, each written for real people, not researchers. We’re tracking 28 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07400471RecruitingEarly Phase 1
Pain relief before root canal: a medicine combination
This trial tests whether a combination of pain medicines given before a root canal can lower pain afterward. It is for people who have moderate to severe tooth pain and are healthy enough for standard treatment.
Chittagong, ChattogramAges 18 years+ - NCT07568405Enrolling by invitation
How Remifentanil Affects Pain Sensitivity During Surgery
This study tests how a pain-relief medication called remifentanil changes the way your body responds to pressure pain. Researchers will measure your pain sensitivity before and after receiving this medication to better understand how it works.
Brussels, Brussels CapitalAges 18–65 - NCT07178288Recruiting
Pain sensitivity test for tennis elbow patients
This study measures how sensitive your elbow is to pressure and how your body controls pain, comparing people with and without tennis elbow. It aims to understand pain processing in tennis elbow.
Zarqa, Zarqa GovernorateAges Up to 60 years - NCT04014829Recruiting
Study of pain processing after planned hysterectomy
This trial looks at how the nervous system and fear of pain may affect pain after a planned hysterectomy. If you qualify, you may be asked about pain levels and pain sensitivity to better understand who may have more pain recovery challenges.
SingaporeAges 21–80 - NCT06133933Enrolling by invitation
Shoulder replacement and pain medication study
This study looks at how your pain tolerance before a total shoulder replacement might relate to how much pain medication you need after surgery. The goal is to help doctors better manage pain medication after surgery.
Camden, New JerseyAges 18 years+ - NCT07123805Recruiting
Acupuncture for knee replacement recovery
This study tests if adding acupuncture before and after knee replacement surgery helps reduce pain and improve recovery. It may be an option for people having planned knee replacement for osteoarthritis.
Pavia, PaviaAges 18 years+ - NCT05654012Recruiting
Study of migraine risk in teens and kids
This study looks at how migraine may start or affect children by comparing young people who either have migraine symptoms or are at higher risk. It may help researchers understand migraine patterns and who could benefit from early prevention.
St Louis, MissouriAges 10–13 - NCT06068907Enrolling by invitation
Elbow Pain: Sensitivity to Pressure
This study is looking at how people with long-lasting elbow pain (at least 3 months) feel pressure. It aims to understand pain better for future treatments.
Istanbul, BakırkoyAges 18–65 - NCT07513974Recruiting
Pain sensitivity test to predict opioid needs in heart surgery
This study measures how sensitive you are to pain using a special device, then tracks how much pain medication you need during heart surgery. The goal is to see if pain sensitivity can predict opioid requirements and help doctors customize pain control for you.
Brussels, AnderlechtAges Any age - NCT07148921Recruiting
Pain perception during gender affirming hormone therapy
This study looks at how starting gender affirming hormone therapy may change your experience of pain. If you are an adult assigned female at birth planning to start testosterone, or an adult assigned male at birth planning to start estradiol, and you have not taken any sex hormones in the past six months, this trial wants to measure your pain perception over time.
Vienna, State of ViennaAges 18 years+ - NCT05009433Recruiting
Exercise plans in pregnancy and afterward for mom and baby health
This study compares two types of exercise—short, intense intervals versus moderate steady activity—during pregnancy and looks at effects on mothers and children. It also checks how participants do on health, fitness, and well-being tests before, during, and after pregnancy.
Gdansk, Pomeranian VoivodeshipAges 18–45 - NCT07269925Recruiting
How different electrical frequencies affect muscle strength and pain
This study tests whether changing the electrical frequency during a type of nerve stimulation (percutaneous neuromodulation) can improve muscle strength and reduce pain sensitivity in people with a hidden muscle knot (trigger point) in the shoulder blade area.
Krakow, PolandAges 18–65 - NCT07128043Enrolling by invitation
Cassava wax baths for trigger finger pain and function
This study tests whether warm baths made from cassava (tapioca) wax can reduce pain, improve hand function, and help with the catching or locking feeling in people with trigger finger. If you have trigger finger and no other major hand problems, this treatment may offer a gentle, non-surgical option.
Chiang Rai, Tha SutAges 40–70 - NCT07217782Recruiting
Pain in Juvenile Arthritis Study
This study looks at pain in kids with juvenile arthritis compared to healthy kids. It may help researchers understand pain better and improve future treatments.
St Louis, MissouriAges 9–17 - NCT06899685Recruiting
Kinesio taping vs. tool-assisted massage for neck pain relief
This study compares two non-invasive treatments for neck pain caused by muscle knots in the upper trapezius (the muscle between your neck and shoulder). The goal is to see which approach better reduces pain, improves neck movement, and helps with daily function.
Banī SuwayfAges 19–23 - NCT07692126Recruiting
Neck pain and hand strength: core vs shoulder exercises
This study compares two types of exercises to see which better improves hand grip strength and neck pain. If you have had chronic myofascial neck pain (trigger points) in the upper shoulder muscle for over 6 months, this trial may help find which exercise works best for you.
Giza, Giza GovernorateAges 25–45 - NCT06851091Recruiting
Fibromyalgia study on pain sensitivity and balance
This study looks at how fibromyalgia affects your sensitivity to pain and your sense of balance. It may help find better ways to treat these symptoms.
Istanbul, ÜsküdarAges 18–65 - NCT07514208Enrolling by invitation
Headache Sensitivity and Pain Testing Study
This study examines how sensitive the skin and tissues around the head are in people with migraines or tension headaches. Researchers will perform gentle touch and pressure tests to understand pain patterns, which may help improve headache treatment in the future.
Barcelona, BarcelonaAges 18 years+ - NCT07114913Recruiting
Carpal tunnel symptom location and pain study
This study looks at where carpal tunnel syndrome symptoms show up and how your body processes pain. By understanding this, doctors hope to find better ways to treat it.
Istanbul, UsküdarAges 18–65 - NCT07533409Recruiting
Touch and Pain Sensitivity in Children with Writing Difficulties
This study measures how sensitive children are to touch and pain, and tests their hand strength. Researchers want to understand if children who struggle with writing have different sensory abilities than other children their age.
EdirneAges 6–12 - NCT06357715Recruiting
Nerve stretching in healthy adults: pain threshold study
This study tests a gentle nerve stretching technique (called 'slump neurodynamic mobilization') in healthy adults to see if it changes how they sense pain. Researchers want to learn how much pressure feels uncomfortable before and after the exercise.
RouenAges 30–65 - NCT07282522Recruiting
Sensory and function in cervical disc herniation
This study looks at how cervical disc herniation affects sensation and daily function. If you have had neck pain for at least 3 months and have been diagnosed with cervical disc herniation, researchers want to compare your results to people without neck pain.
Iğdır, IğdirAges 18–65 - NCT06765486Recruiting
Exercise and pain relief: arm vs leg training
This trial compares how resistance training of the arms versus legs affects your body's natural ability to reduce pain. It may help understand which type of exercise is best for managing pain.
MadridAges 18–64 - NCT07640620Recruiting
How nerve sensitivity relates to heel pain
This study looks at whether people with plantar fasciitis (painful heel condition) have heightened nerve sensitivity, and how this connects to their symptoms. Researchers will compare your pain patterns and nerve responses to those of healthy volunteers to better understand what drives heel pain.
IstanbulAges 18–65
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Common questions
- Are there clinical trials for pain threshold?
- Yes. Clin2 currently lists 28 recruiting pain threshold studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain threshold trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain threshold trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.