Clinical trials · Cleveland, OH
Pain clinical trials in Cleveland
We’re tracking 36 recruiting pain studies with a site in or near Cleveland — including Phase 1, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Cleveland
- NCT07174440Recruiting
Testing numbing medicine for spine surgery
This trial is testing a numbing medicine placed near the spine (erector spinae block) during lumbar spine fusion surgery. It aims to see if it helps control pain and may reduce the amount of anesthetic needed during the procedure.
Cleveland, OhioAges 21–75 - NCT04218617RecruitingPhase 2
One vs two radiation treatments for spine metastases
This trial tests whether giving radiation to a spine metastasis in one dose works as well as giving it in two smaller doses. It aims to control tumors while keeping side effects and risk to the spinal cord low.
Cleveland, OhioAges 18 years+ - NCT05484635Recruiting
Test removing mesh versus leaving it for groin pain
This study compares removing the pre-surgery mesh versus not removing it in people who have long-lasting groin pain after inguinal hernia repair. It may help doctors learn which approach best reduces ongoing pain.
Cleveland, OhioAges 18 years+ - NCT07006675RecruitingPhase 3
NSAIDs for Tibia Fracture Pain and Healing Study
This study tests whether NSAID pain relievers (like ibuprofen) affect bone healing after a broken tibia and if they can help reduce the need for stronger painkillers. If you qualify, you could help doctors learn the safest way to manage pain after this common injury.
Cleveland, OhioAges 18–80 - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT05580419Recruiting
Program training to improve chronic pain care
This trial tests whether a 4PCP training program for primary care clinicians improves both clinician and patient outcomes for people living with chronic non-cancer pain. If you have long-lasting pain and can take part in questionnaires and visits, your participation may help evaluate whether this program leads to better care and results.
Cleveland, OhioAges 14–80 - NCT01550575Recruiting
Study of outcomes in people treated with Boston Scientific devices
This study looks back at what happened to patients after treatment (or if they could have used) Boston Scientific medical devices. It may help improve how these devices are used and understand real-world results.
Cleveland, OhioAges 18 years+ - NCT07756541Recruiting
Online music and movement program for chronic pain
This study tests whether an online program combining music and gentle movement can help reduce chronic pain. It uses sessions you can do at home with your own device.
Cleveland, OhioAges 18 years+ - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Cleveland, OhioAges 2 months–17 years - NCT06845631Recruiting
Study of Freedom PNS for chronic pain
This study looks at how well the Freedom PNS system works for people who already have it implanted. It helps doctors learn more about treating chronic pain with this device.
Cleveland, OhioAges 18 years+ - NCT07222462Recruiting
Radiofrequency ablation for chronic low back pain
This study tests if radiofrequency ablation, a procedure that uses heat to block pain signals from the facet joints in your spine, can help people with long-term low back pain that hasn't improved with other treatments like physical therapy.
Cleveland, OhioAges 18 years+ - NCT07091123RecruitingPhase 4
Comparing two treatments for chronic back pain after surgery
This study compares two treatments for long-term back pain after surgery: a spinal cord stimulator (a device that sends mild electrical pulses to your spine) and a pump that delivers pain medicine directly to your spinal fluid. It will look at which treatment you prefer and how well it works over time.
Cleveland, OhioAges 30 years+ - NCT06528574Recruiting
Pain after root canal cleaning methods
This trial compares two methods of cleaning a tooth's root canal to see which causes less pain after the procedure. It is for people with a specific type of tooth nerve pain (acute pulpitis) in a lower back molar.
Cleveland, OhioAges 18–50 - NCT06526572Recruiting
Pain measurement with brain waves in tooth infection
This trial tests a new way to measure pain from a tooth infection using brain wave recordings (EEG). It may help people whose numbing injection doesn't work well.
Cleveland, OhioAges 18–50 - NCT07117032RecruitingPhase 1
Radiation therapy for cancer-related stomach pain
This trial tests a type of radiation therapy (SBRT) to treat severe stomach pain caused by cancer pressing on nerves near the stomach. It aims to provide pain relief without the need for a standard nerve block procedure.
Cleveland, OhioAges 18 years+ - NCT06510244Recruiting
Measuring pain during dental treatment with brain waves
This trial uses EEG (a brain-wave test) and a pain scale to measure how much discomfort you feel during dental treatment on your upper front tooth. It may help dentists understand pain better and improve care.
Cleveland, OhioAges 20–60 - NCT05811312Recruiting
Spinal cord stimulation and brain changes in chronic pain
This study uses non-invasive brain monitoring to see how spinal cord stimulation may change brain activity in people with chronic nerve pain. It aims to better understand how treatment affects the brain and pain over time.
Cleveland, OhioAges 18 years+ - NCT04883411Recruiting
First-in-human test of new cervical spine plate and cage
This study tests a new implanted metal plate and cage to treat problems in the neck caused by worn spinal discs and nerve or spinal cord compression. It is aimed at people whose symptoms have not improved with non-surgical care for at least 6 weeks (or who have worsening nerve/spinal cord symptoms).
Cleveland, OhioAges 22–79 - NCT05868668Recruiting
Low-intensity shockwave versus wave therapy for erectile and pelvic pain
This trial compares two types of low-intensity wave therapy to see which works better for erectile dysfunction and/or chronic pelvic pain. Participants may benefit if these therapies improve erection quality and reduce pelvic pain.
Cleveland, OhioAges 40 years+ - NCT06538233RecruitingPhase 2
Pain after buffered vs. non-buffered numbing medicine
This trial compares two versions of a numbing medicine (articaine) to see which causes less pain during dental work on upper front teeth.
Cleveland, OhioAges 18–60 - NCT07026786Recruiting
Mindfulness for recovery after colorectal surgery
This study tests whether adding mindfulness sessions to your standard recovery plan helps you heal better after bowel surgery. You'll use a phone or tablet app to guide your mindfulness practice during your hospital stay.
Cleveland, OhioAges 18 years+ - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT07791966Recruiting
Brain stimulation for chronic pain
This study tests a non-invasive brain stimulation technique to help people with chronic pain, specifically Complex Regional Pain Syndrome (CRPS), manage pain-related avoidance behaviors. It may help reduce pain and improve daily function.
Cleveland, OhioAges 18 years+
Hear when a new Pain trial opens near Cleveland, OH
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Pain trials in other cities
Where these studies are running near Cleveland
Institutions with a site for the recruiting pain studies listed above.
- Cleveland Clinic · 8 studies
- University Hospitals Cleveland Medical Center · 6 studies
- Cleveland Dental Institute · 4 studies
- MetroHealth Medical Center · 3 studies
- Case Western Reserve University
- Louis Stokes Cleveland VA Medical Center
- Rainbow Babies and Children's Hospital
- Western Reserve Spine and Pain Institute
What taking part in a pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting pain studies in Ohio.
Common questions
- Are there pain clinical trials near Cleveland?
- Yes. We're currently tracking 36 recruiting pain studies with a site near Cleveland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a pain study near Cleveland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Cleveland to take part?
- Not necessarily. These studies have a site near Cleveland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New pain studies open near Cleveland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.