Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,261 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06878417Recruiting
Cannabinoids for osteoarthritis knee or hip pain
This study tests if cannabinoid medications can reduce pain interference in daily life for people with hip or knee osteoarthritis. It may be a new option for moderate to severe pain.
Toronto, OntarioAges 40–80 - NCT06884332Recruiting
Spinal radiation for bone pain from cancer
This trial tests a specific type of radiation therapy for bone pain caused by cancer that has spread to the spine. It aims to improve pain relief and quality of life.
Brest, BrestAges 18 years+ - NCT06885931Recruiting
Nerve stimulation trial for mixed urinary incontinence
This trial tests a new implant that stimulates a nerve in your pelvic area to help control both stress and urge urine leaks. It might be an option if you've tried other treatments like bladder training or medicine and they didn't help enough or caused side effects.
Leuven, Herestraat 49Ages 22 years+ - NCT06888791Recruiting
Hydro dissection for frozen shoulder: ultrasound vs X-ray guidance
This trial compares two ways to guide a fluid injection for frozen shoulder—one using ultrasound and one using X-ray. The goal is to see which technique works better to reduce pain and improve movement.
AnkaraAges 18–80 - NCT06891690Recruiting
Brain stimulation for neurological and gynecological conditions
This trial tests whether a gentle brain stimulation technique called tDCS can help people with neurological problems (like weakness in arms or legs) or certain gynecological conditions (like endometriosis or painful periods) who are not using other treatments. It aims to see if tDCS can improve symptoms.
PoznanAges 18–90 - NCT06892743Recruiting
Comparing two pain blocks for kidney removal surgery
This trial compares two ultrasound-guided nerve blocks to see which one provides better pain relief for patients undergoing open kidney removal (nephrectomy). If you have kidney cancer and are scheduled for this surgery, you may be able to join.
Maadi, Cairo GovernorateAges 18–70 - NCT06899841RecruitingPhase 2/Phase 3
Dexmedetomidine in a nerve block for kidney stone surgery
This study tests whether adding a medicine called dexmedetomidine to a nerve block (an injection near the spine) can improve pain relief after kidney stone surgery. It is for people who are generally healthy and scheduled for a kidney stone procedure.
Asyut, Assiut GovernorateAges 18–70 - NCT06902805RecruitingPhase 2/Phase 3
Testing botox injections and splints for thumb arthritis pain
This study tests if botox injections into the thumb joint, along with a custom splint, can reduce pain from thumb base arthritis. It may be an option if you have persistent pain and have not had recent thumb surgery or certain other treatments.
Paris, Île-de-France RegionAges 18 years+ - NCT06903442Recruiting
Helping ER chest pain patients understand heart risk
This study is testing a new way to talk with people about their heart health after they come to the Emergency Room with chest pain. It aims to help you understand your risk and what you can do to prevent future problems.
EdinburghAges 18 years+ - NCT06912386Recruiting
Ear device for period pain relief study
This trial tests a device that gently stimulates a nerve in your ear to see if it eases menstrual cramps. It may offer a drug-free option for managing period pain.
Chengdu, SichuanAges 18–45 - NCT06912646Recruiting
Laser therapy for foot pain from idiopathic neuropathy
This trial tests a laser device for temporary relief of foot pain from peripheral neuropathy when the cause is unknown. It may help if you have constant foot pain and are not diabetic.
Miramar, FloridaAges 22 years+ - NCT06913868Recruiting
Comparing two types of physical therapy for fibromyalgia pain
This study compares a standard physical therapy approach with one based on group consensus to see which works better for fibromyalgia pain. It may help find a more personalized treatment for your condition.
CairoAges 18–65 - NCT06913920Recruiting
Comparing therapies for hand swelling and pain after wrist fracture surgery
This trial tests whether using mechanical devices (like compression or massage) reduces swelling and pain better than standard care after wrist fracture surgery. It may help you recover hand function more comfortably.
CairoAges 18–65 - NCT06914557RecruitingPhase 2
Scrambler therapy plus duloxetine for chemo nerve pain
This study tests whether adding a non-invasive device called Scrambler Therapy to the usual nerve pain medicine (duloxetine) can better relieve chemotherapy-induced nerve pain. It is for people with cancer who still have significant nerve pain despite taking duloxetine.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06915012Recruiting
Test of light therapy for long-term severe arthritis pain
This study tests a non-drug therapy called biophoton therapy to see if it can reduce chronic severe arthritis pain. It may be an option if you've had pain for at least 3 months and are not using certain medical implants.
Butler, PennsylvaniaAges 18–80 - NCT06915558Recruiting
Reducing inflammation in weight loss surgery
This trial tests a method to control inflammation during bariatric surgery. It may help patients recover better and have fewer complications.
Barcelona, BarcelonaAges 18–65 - NCT06916676Recruiting
Laser therapy for knee osteoarthritis pain
This study tests a type of laser treatment called HILT to see if it can help reduce knee pain from osteoarthritis. You would attend 3 sessions each week for 4 weeks.
CairoAges 18–65 - NCT06917404RecruitingPhase 3
Knee osteoarthritis pain study: comparing a new injection to placebo
This phase 3 study tests whether a medicine called pentosan polysulfate sodium (PPS), given as a shot under the skin, reduces pain in people with knee osteoarthritis. It compares PPS to a placebo (a shot with no active medicine) to see if it is safe and effective.
Peoria, ArizonaAges 18 years+ - NCT06920459Recruiting
Zimmer Biomet Shoulder Replacement Study
This study is testing a shoulder replacement system made by Zimmer Biomet to see how well it works for people with severe shoulder problems, like arthritis or fractures. If you qualify, you would receive the implant and be asked to come back for regular checkups to track your recovery.
PforzheimAges 20 years+ - NCT06928740Recruiting
Music app vs. gas for anxiety during back injection
This trial tests whether listening to a digital music app can reduce anxiety as well as a standard gas (laughing gas) does in people getting a CT-guided back injection for low back pain.
NîmesAges 18 years+ - NCT06932783Recruiting
Electrical stimulation for pain and depression in cirrhosis
This study tests a gentle electrical stimulation device (like a TENS unit) to see if it can help with both pain and depression in people with cirrhosis. It is a non-drug treatment that you can use at home.
Ann Arbor, MichiganAges 18 years+ - NCT06933498Recruiting
Nerve block for less pain meds in back surgery
This trial tests whether a nerve block (called an erector spinae plane block) given before surgery can reduce the amount of pain medicine and anesthesia needed during lumbar disc surgery. It may help people have less pain and fewer side effects.
AnkaraAges 18–75 - NCT06934421Recruiting
A new approach for knee radiofrequency ablation
This trial tests a revised method for radiofrequency ablation to treat chronic knee pain from severe osteoarthritis (KL grade III or IV). It aims to see if the procedure can help patients who haven't gotten relief from standard treatments like physical therapy, painkillers, and steroid injections.
FaroAges 18 years+ - NCT06941636RecruitingPhase 3
Botox for jaw muscle pain from TMD
This trial tests whether Botox injections can reduce jaw and face muscle pain in people with temporomandibular disorders (TMD). It is for those who have had moderate to severe pain for at least 3 months and have not received Botox recently.
StockholmAges 18–50
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,261 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.