Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,136 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07369024RecruitingPhase 2
Study of low-dose ketamine for sickle cell pain crisis
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Torrance, CaliforniaAges 5–20 - NCT07356115Recruiting
Pain patterns and pain location in muscle and sports clinics
This study looks at whether people's pain patterns—measured by a simple questionnaire called PainDETECT—are linked to where their pain is and what caused it. It may help doctors better understand and treat different types of pain.
IstanbulAges 18 years+ - NCT05351099Recruiting
Nerve-block shot for emergency dental pain relief
This study tests whether a dental nerve-block shot can safely help reduce pain for adults who come to the emergency department with tooth pain. If the ED clinician plans to use the block, you may be asked to rate your pain during the visit.
Fresno, CaliforniaAges 18 years+ - NCT07351851Recruiting
Exercise for back pain and urine leakage in women
This study tests whether a special exercise program called PEMM (which combines pelvic floor and core exercises) can help women with both chronic low back pain and urinary incontinence. It is designed for women who have had back pain and urine leakage for at least 3 months.
Doha, Baladiyat ad DawhahAges 18–65 - NCT07338877Enrolling by invitation
Stem cell therapy for disc-related low back pain
This trial tests a new treatment that uses your own stem cells to help heal damaged discs in your lower back. The stem cells are injected into the disc during a minimally invasive procedure to reduce pain and improve function.
Košice, Košice RegionAges 18 years+ - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07332845Recruiting
Neck and hamstring therapy for chronic pain
This trial tests a special exercise technique that combines shoulder blade and pelvis movements to see if it helps people with long-term neck pain and tight hamstrings.
Karachi, SindhAges 18–40 - NCT07328126Recruiting
Muscle energy technique for low back pain relief
This trial tests a gentle muscle stretching method (muscle energy technique) on the latissimus dorsi muscle to see if it reduces pain, improves daily function, and increases spine movement in people with long-term low back pain.
Rawalpindi, Punjab ProvinceAges 30–55 - NCT06869928Recruiting
Pain and irritability pathway for children with neurological conditions
This study tests a special care plan for children who have both a significant neurological condition and unexplained pain or irritability. The goal is to help families and doctors work together to better understand and manage these distressing symptoms.
Vancouver, British ColumbiaAges 6 months–18 years - NCT06869668Recruiting
Chronic low back pain and quality of life study
This study looks at how long-term back pain affects your daily life, physical abilities, and how you feel about moving. It aims to find links between pain, fear of movement, and overall well-being.
Istanbul, BuyukcekmeceAges 18–50 - NCT06328751Recruiting
Virtual reality meditation for cancer pain relief
This study tests whether using meditation with virtual reality can help reduce pain in people with cancer. If you have chronic pain from cancer and can use a simple VR headset, this might be a gentle way to find relief.
Manaus, AmazonasAges 18–75 - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT06696573Recruiting
Anti-inflammatory drugs for pain during medical abortion
This study tests whether giving anti-inflammatory drugs before or during a medical abortion (13–22 weeks) can help prevent pain better than treating pain once it starts. If you're eligible, taking part may help improve pain management for future patients.
Ho Chi Minh CityAges 18 years+ - NCT07308873Recruiting
Gait and knee osteoarthritis pain study
This study looks at how walking patterns relate to knee pain from osteoarthritis. It aims to understand individual differences to improve future treatments.
Pittsburgh, PennsylvaniaAges 45–80 - NCT07308730Recruiting
Pain diary after gallbladder surgery
This study looks at whether using a pain diary can help people manage pain better after gallbladder removal surgery. If you are having this surgery for the first time and can read and write in Turkish, you may be able to join.
Muğla, MenteşeAges 18 years+ - NCT07288047Recruiting
Virtual reality for pain during early abortion
This study tests if using a virtual reality headset during a first trimester procedural abortion can help reduce pain and anxiety. You may be eligible if you are planning to have an abortion at Planned Parenthood of Western Pennsylvania and meet the criteria below.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Birmingham, AlabamaAges 18 years+ - NCT07281651Recruiting
Understanding pain sensitivity in knee pain and fibromyalgia
This study looks at how the brain and nerves process pain in people with knee pain or fibromyalgia. It compares them to pain-free people to understand differences in muscle signals.
Derby, DerbyshireAges 40 years+ - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT07278804Recruiting
Pain control options for IUD insertion
This study tests different pain control choices during IUD placement. It may help you find what works best for your comfort.
Durham, North CarolinaAges 18–50 - NCT06069362Recruiting
Manual Physiotherapy for Neck and Arm Pain
This study tests whether a type of hands-on physical therapy (manual therapy) can help reduce neck and arm pain. It looks at how your body senses touch and pressure to see if that predicts how well you respond.
San Sebastián, GipuzkoaAges 18–80 - NCT07264270RecruitingPhase 1
A new injection for long-term sciatica pain
This trial tests a new medicine called C-1101, given as a shot into the spine, to see if it safely reduces pain from chronic sciatica. It is for people who have not gotten enough relief from standard treatments.
Broadmeadow, New South WalesAges 18–65 - NCT06731335RecruitingPhase 2
Psilocybin for chronic nerve pain that hasn't improved with other treatments
This study tests whether psilocybin (a compound found in certain mushrooms) can help reduce chronic nerve pain that has not responded well to standard medications. You will receive study treatment plus psychotherapy to see if it improves your pain.
Toronto, OntarioAges 18–65 - NCT04898491Recruiting
Pain behavior scale study for adults who cannot speak
This study checks whether a “pain behavior” checklist works well and gives consistent results in adults who can’t communicate verbally and who have an artificial airway. It may help clinicians better recognize pain in people who cannot tell them directly.
Madrid, MadridAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,136 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.