Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06113211RecruitingPhase 4
Non-opioid pain control after fracture surgery
This trial tests a combination of non-opioid medications to manage pain after surgery for a broken bone, aiming to reduce or avoid the use of opioids. It may help you control pain without the risks of strong painkillers.
Detroit, MichiganAges 18–80 - NCT06115083Recruiting
Pelvic floor training for men with chronic pelvic pain
This trial tests if pelvic floor muscle training can reduce chronic pelvic pain in men. It also looks at how well patient-reported symptoms match physical exam findings.
StockholmAges 18 years+ - NCT06119698Recruiting
Improving Health for Older Adults With Pain Through Engagement
This study tests a program to help older adults with long-lasting bone, joint, or muscle pain become more active. Participants wear a smartwatch and get support to manage their pain and improve their health.
Boston, MassachusettsAges 55 years+ - NCT06141720Recruiting
Mindfulness for endometriosis surgery
This trial tests if a mindfulness program can help people preparing for endometriosis surgery. It may reduce stress and improve recovery.
Hershey, PennsylvaniaAges 18 years+ - NCT06149819Recruiting
Chest pain nurse track for emergency care
This trial is testing a nurse-led care pathway for people who come to the emergency room with chest pain that is not caused by an injury. The goal is to see if this approach can improve care and speed up the process.
Grenoble, GrenobleAges 18 years+ - NCT06160778RecruitingPhase 3
Comparing two pain medicines for kids with belly pain
This study compares two common pain relievers—ketorolac and morphine—given through an IV to children with acute abdominal pain. It aims to find which works better and has fewer side effects for this condition.
Calgary, AlbertaAges 6–17 - NCT06168604Recruiting
Pain communication toolkit for dementia caregivers
This trial tests a toolkit to help caregivers of adults with dementia and chronic pain better identify and communicate about their loved one's pain. You and the person you care for may join if you meet the listed requirements.
New York, New YorkAges 21 years+ - NCT06218784RecruitingPhase 1
Testing a new drug for safety in healthy people and those with nerve pain after shingles
This study tests an experimental drug, iN1011-N17, to see how safe it is and how the body processes it. It involves healthy volunteers and people with postherpetic neuralgia (nerve pain after shingles). This may help find better treatments for this type of chronic pain.
Adelaide, South AustraliaAges 18–75 - NCT06225817Recruiting
Can a placebo help with chronic jaw pain and sleep?
This study is testing whether a placebo (a pill with no medication) can help improve sleep and reduce pain for people with long-term jaw or face pain. Researchers want to see if just expecting relief can change how your body handles pain.
Baltimore, MarylandAges 18–88 - NCT06244732Recruiting
Pain control after open aneurysm surgery
This study tests two different ways to manage pain after open surgery for an abdominal aortic aneurysm. It compares a standard pain control method to another approach that may reduce the need for strong painkillers.
San Donato Milanese, MilanAges 18 years+ - NCT06290024Recruiting
Nerve pain study: tracking long-term symptoms
This study follows people with nerve pain over time to learn more about their condition. You will not receive a new treatment, but your data will help doctors understand neuropathic pain better.
Shanghai, YangpuAges 18–85 - NCT06297447Recruiting
Keeping it Simple: rehab for chronic pain
This study looks at how to better help people with ongoing muscle or joint pain who are getting rehabilitation through their local municipality. The goal is to learn what works best for you.
Holbæk, Region SjællandAges 18 years+ - NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT06328751Recruiting
Virtual reality meditation for cancer pain relief
This study tests whether using meditation with virtual reality can help reduce pain in people with cancer. If you have chronic pain from cancer and can use a simple VR headset, this might be a gentle way to find relief.
Manaus, AmazonasAges 18–75 - NCT06344169RecruitingPhase 2/Phase 3
Pain relief after C-section with Naldebain
This trial tests a long-acting painkiller, Naldebain, for women having a planned C-section. It aims to see if it provides better pain control after the surgery.
Dalin, Chai-YiAges 20 years+ - NCT06351839Recruiting
Sleep better despite long-term pain
This trial tests a program to help people with chronic pain and insomnia sleep better. It focuses on combining pain management with sleep improvement strategies.
Tromsø, Troms CountyAges 18–75 - NCT06373978RecruitingPhase 4
Non-narcotic pain relief after elbow needle procedure
This study tests non-narcotic pain medicine after a needle procedure for chronic elbow tendon pain. It compares different pain-relief options to find what works best without opioids.
Coral Springs, FloridaAges 18–65 - NCT06393101RecruitingPhase 1
High-CBD cannabis extract for complex regional pain syndrome treatment
This study tests a high-CBD cannabis extract (BRC-002) to see if it can help reduce pain and improve health in people with Complex Regional Pain Syndrome (CRPS). Participants will not use opioids or other cannabis during the study.
La Jolla, CaliforniaAges 21–75 - NCT06397157Recruiting
Virtual reality and motor imagery for neck pain
This study tests whether combining virtual reality with mental practice of movements can help reduce long-term neck pain. If you have had non-specific neck pain for at least three months, this treatment may help retrain how your brain controls your neck muscles.
Rawalpindi, Punjab ProvinceAges 18–50 - NCT06402409Recruiting
Studying multiple health conditions in spinal pain patients
This study looks at people who have neck or back pain along with other health conditions. It aims to understand how these conditions together affect your health and well-being.
AalborgAges 18 years+ - NCT06413277Recruiting
ECAP-controlled spinal cord stimulation for chronic pelvic pain
This trial tests a new type of spinal cord stimulator that uses closed-loop technology to treat chronic pelvic pain caused by a known injury. It may be an option if your pain is severe and hasn't responded to other treatments.
New York, New YorkAges 18 years+ - NCT06447545Recruiting
Comparing air pressure levels for gallbladder surgery pain
This trial compares two different air pressure levels used during laparoscopic gallbladder removal to see which one causes less pain after surgery, including shoulder pain and bile duct injuries.
Lahore, PUNAges Any age - NCT06454669RecruitingPhase 2
Dronabinol added to opioids for chronic low back pain
This trial tests whether adding dronabinol (a prescription medication derived from cannabis) to your current opioid pain treatment can help reduce chronic low back pain more effectively. It is for people who have had persistent low back pain for at least 3 months and are already on a stable opioid regimen.
Houston, TexasAges 18–64 - NCT06466330Recruiting
Knee embolization for post-replacement pain
This trial tests a non-surgical treatment called microparticle geniculate artery embolization for people with persistent knee pain after a total knee replacement. It aims to reduce pain by blocking tiny blood vessels that may be causing inflammation.
CréteilAges 40–80
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.