Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07351981Enrolling by invitation
Cooled radiofrequency for knee osteoarthritis pain
This study tests a new approach called cooled radiofrequency (TcPRF) to calm knee pain from osteoarthritis. It may be an option if standard treatments haven't worked and you haven't had certain other treatments recently.
AthensAges 45 years+ - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT07334652Enrolling by invitation
Managing pain and comfort during eye exams for premature babies
This study tests different methods to manage pain and comfort in premature infants during their first eye exam for retinopathy of prematurity. It may help find ways to make the exam less stressful for babies.
Erzurum, YakutiyeAges birth–1 month - NCT07326163Enrolling by invitation
Peppermint oil aromatherapy for fibromyalgia pain relief
This study tests whether smelling peppermint oil can help reduce pain and improve daily function in people with fibromyalgia, while also looking at cost. It uses a simple, non-invasive method (aromatherapy) to see if it can be a helpful addition to your current care.
Bilecik, BilecikAges 18 years+ - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT07311889Enrolling by invitation
Patient satisfaction with ELIXIR MD during plastic surgery recovery
This study looks at how satisfied patients are with their recovery after plastic surgery when the ELIXIR MD device is used. It aims to understand if this device helps improve the recovery experience.
Irvine, CaliforniaAges 18 years+ - NCT07310823Enrolling by invitation
Manual therapy for neck-related headaches
This study tests if manual therapy (hands-on treatment) can help people whose headaches start from neck problems. If you have headaches at least once a week and limited neck movement, this trial may be an option.
GizaAges 20–40 - NCT07304037Enrolling by invitation
Skin-to-skin contact after birth for pain and satisfaction
This study looks at whether holding your baby skin-to-skin right after birth can help reduce your pain, improve your satisfaction with the birth, and affect your vital signs. If you had a healthy, full-term pregnancy and a vaginal birth without pain medication, you may be able to join.
IstanbulAges 18 years+ - NCT07287657Enrolling by invitation
Electrical acupoint stimulation after chest surgery
This trial tests a gentle, non-needle therapy that stimulates acupoints with mild electrical current to help you recover better after chest surgery. It may reduce pain and speed healing.
Taipei, HualienAges 15 years+ - NCT07256626Enrolling by invitation
Soundwave Wellness Study for Back Pain
This trial tests a soundwave-based wellness program for back pain. It's a simple study that asks you to follow instructions, so if you're interested in trying a non-invasive approach, this could be a good fit.
New York, New YorkAges Any age - NCT07239700Enrolling by invitation
Buzzy and TickleFlex for easier insulin shots in kids
This study tests two devices, Buzzy and TickleFlex, to see if they can reduce pain and fear during insulin injections in children with type 1 diabetes. It may help make daily injections more comfortable.
Hakkari, CentreAges 6–12 - NCT07238595Enrolling by invitation
Neck Pain and Body Awareness in Healthy Older Adults
This study looks at how neck pain relates to your body's ability to sense where your neck is in space (proprioceptive awareness). It is for healthy older adults who can live independently and want to help researchers understand this connection.
IspartaAges 65 years+ - NCT07219888Enrolling by invitationPhase 4
Comparing suzetrigine and oxycodone for knee replacement pain
This study compares a new pain medicine called suzetrigine with a commonly used opioid, oxycodone, for pain after a knee replacement. The goal is to see which works better and has fewer side effects.
Louisville, KentuckyAges 21–89 - NCT07215546Enrolling by invitation
Stopping pain after heart surgery with a special chest closure
This trial tests a new device to close the breastbone after open-heart surgery to see if it helps reduce the need for prescription pain medicine. The device is designed to hold the bone together more securely, which may lead to less pain and faster recovery.
Naples, FloridaAges 19–80 - NCT07209280Enrolling by invitation
New screw system for pelvic fracture repair
This trial tests a newer type of screw to fix certain pelvic fractures. It aims to see if it works better than the standard screw for helping bones heal and for you to get back on your feet.
Salt Lake City, UtahAges 18–80 - NCT07167394Enrolling by invitation
Virtual reality glasses for kids' dental pain relief
This trial tests whether virtual reality (VR) goggles can reduce pain during dental treatment in children aged 6 to 10 who have never been to the dentist before and have a cavity in a back tooth.
Ankara, YenimahalleAges 6–10 - NCT07155876Enrolling by invitation
Aromatherapy for comfort during labor
This study tests whether aromatherapy (using pleasant scents) can help with comfort during labor. It is open to pregnant women in labor, even if they end up needing a C-section.
Miami, FloridaAges 18 years+ - NCT07145346Enrolling by invitationPhase 4
Suzetrigine for pain relief after multiple rib fractures
This trial tests a new medicine, suzetrigine, for managing acute pain in adults who have broken three or more ribs from a blunt injury. It aims to see if this painkiller works well and is safe for you.
Orange, CaliforniaAges 18 years+ - NCT07141992Enrolling by invitation
Nerve glide exercises for burning pain from diabetic neuropathy
This study compares two types of nerve gliding exercises to see which works better for reducing burning pain, improving muscle strength, and increasing movement in patients with diabetes-related nerve damage.
Karachi, SindhAges 40–65 - NCT07129096Enrolling by invitation
Digital relaxation training for jaw pain
This study tests if a digital relaxation program can help reduce jaw pain caused by temporomandibular disorders (TMD). It may be a good option if you have jaw muscle or joint pain and want to try a non-drug approach.
OuluAges Any age - NCT07126197Enrolling by invitation
Lymphovenous bypass for diabetic nerve pain
This study tests if a surgery called lymphovenous bypass can reduce nerve pain caused by diabetes. It may help people with diabetic peripheral neuropathy, even if they have foot ulcers.
TaipeiAges 20–80 - NCT07102121Enrolling by invitation
Comparing tooth sensitivity after cementing crowns with two dental materials
This study tests whether one type of dental cement causes less tooth sensitivity than another after placing a crown. The results could help your dentist choose the material that feels better for you.
Mingora, Khyber PakhtunkhwaAges 15–60 - NCT07092605Enrolling by invitationEarly Phase 1
Microdosed semaglutide for longer, healthier life
This trial tests whether a very low ('micro') dose of semaglutide can improve health, quality of life, and how long you live well. It's for people who are interested in the drug's general health benefits but not specifically for weight loss.
Ann Arbor, MichiganAges 18–65 - NCT07083219Enrolling by invitation
Exercise and pain processing in healthy adults
This study tests how aerobic exercise affects the way your body processes pain. If you are a healthy adult without chronic pain, you may be able to join.
El Paso, TexasAges 18–50
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.