Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07694141Recruiting
Pain Relief After Chest Surgery
This trial studies how well different pain medications work after thoracic (chest) surgery. It aims to find the best way to manage pain and improve recovery.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT03446456RecruitingPhase 1/Phase 2
Vasopressin and pain perception study
This trial tests whether vasopressin, a nasal spray, changes how your brain processes pain. You will receive either the spray or a placebo and have an MRI scan to see brain activity.
Baltimore, MarylandAges 18–65 - NCT07684092Enrolling by invitation
Diaphragmatic breathing and electroacupuncture for chronic neck pain
This trial tests whether combining diaphragmatic breathing exercises with electroacupuncture can reduce chronic neck pain. It is designed for people with moderate pain and specific breathing issues.
Lahore, Punjab ProvinceAges 20–50 - NCT07018375Enrolling by invitationPhase 4
Oliceridine for pain after lung surgery
This trial tests a pain medicine called oliceridine, given through a pump you control after lung surgery, to see if it helps prevent long-term pain. It is for people having a VATS procedure to remove part of their lung and who are generally healthy.
TianjinAges 18–75 - NCT06487754Recruiting
Chronic pelvic pain in trans people on testosterone therapy
This study explores why some trans masculine people develop new or worsening pelvic pain after starting testosterone therapy. Researchers want to understand your experience through interviews.
Saint-Martin-d'HèresAges 18 years+ - NCT06494280Recruiting
Epidural method comparison for first-time mothers
This trial compares two ways of giving epidural pain medicine during early labor to see which provides better pain relief for first-time mothers. It may help you have fewer breakthrough pain episodes.
NazarethAges Any age - NCT06495528Recruiting
Virtual reality for pain during port-a-cath placement
This study tests whether a virtual reality program (called Bliss) can help reduce pain and anxiety while you get a port-a-cath placed. It is for people who are having this small device put in for the first time as part of their cancer care.
AngersAges 18 years+ - NCT06495632RecruitingPhase 4
Scheduled or as-needed pain medicine after surgery?
This study compares taking pain medicine on a fixed schedule versus only when you need it after common outpatient surgeries. It aims to find which approach works better for controlling pain and reducing side effects.
Fayetteville, North CarolinaAges 18–65 - NCT06498037RecruitingPhase 4
Better fentanyl dosing for cancer pain
This trial is testing a new way to give fentanyl under the skin for cancer-related pain. The goal is to find the right dose quickly and safely to make sure you get enough pain relief.
Rotterdam, South HollandAges 18–120 - NCT06502457Recruiting
Virtual reality hypnosis for labor pain
This study tests whether using a virtual reality hypnosis program can help manage pain during early labor in women with low-risk pregnancies. If you are in the beginning stages of labor and want a non-drug option for comfort, this might be for you.
AmiensAges 18 years+ - NCT06502795Recruiting
Quad Strengthening for Knee Pain at Different Angles
This study tests whether strengthening your quadriceps (front thigh muscles) at different knee angles can reduce pain behind or around your kneecap. If you have had this type of knee pain for at least 3 months, you may be eligible.
Fortaleza, CearáAges 18–35 - NCT06503432Recruiting
Does PD-L1 affect pain after lung cancer surgery?
This study looks at how a protein called PD-L1 relates to pain after lung cancer surgery. If you're having a VATS procedure, researchers want to see if PD-L1 levels affect your recovery and pain experience.
Beijing, Beijing MunicipalityAges 18–80 - NCT06503523Recruiting
Brain activity during pain and itch
This study tests whether imagining movements changes brain activity when you feel pain or itch. It could help scientists understand how the brain responds to these sensations.
GistrupAges 18–60 - NCT06504277Recruiting
Lower gas pressure during surgery for shoulder pain reduction
This study compares two different gas pressures used during laparoscopic surgery to see if lower pressure reduces shoulder pain afterward. It may help if you're having surgery to remove an ovary, fallopian tube, or ovarian cyst.
Toronto, OntarioAges 18 years+ - NCT06506708Recruiting
Massage and hydrotherapy for endometriosis pain
This study tests whether combining massage and water therapy can reduce pain and improve well-being in people with endometriosis. If you have had pelvic pain for at least 6 months, this trial might help you find relief.
GranadaAges 18–55 - NCT06507761Recruiting
Heat therapy for recent neck pain
This study tests whether heat therapy (like heat packs) can help people with new or recent neck pain that has no specific known cause. You will receive heat treatments and be checked over 4 weeks to see if it reduces pain.
IstanbulAges 18–65 - NCT06508814Recruiting
Pain with different gas pressures during laparoscopic hysterectomy
This trial compares two different gas pressure levels used during laparoscopic hysterectomy (a minimally invasive surgery to remove the uterus) to see which one causes less pain after the procedure. It may help you and your doctor choose the best pressure for your surgery.
Memphis, TennesseeAges 18–80 - NCT06509633Recruiting
Pain education and rehab for carpal tunnel syndrome
This study tests whether combining a special type of pain education with standard rehabilitation helps people with moderate to severe carpal tunnel syndrome feel better and improve hand function. It aims to help you understand your pain and recover.
Lahore, Punjab ProvinceAges 20–50 - NCT06510244Recruiting
Measuring pain during dental treatment with brain waves
This trial uses EEG (a brain-wave test) and a pain scale to measure how much discomfort you feel during dental treatment on your upper front tooth. It may help dentists understand pain better and improve care.
Cleveland, OhioAges 20–60 - NCT06511362Recruiting
Balance or strength training for front knee pain
Researchers want to see which type of exercise program better helps people with front knee pain. You will do either balance challenge training or strengthening exercises to see which reduces your pain more.
Lahore, Punjab ProvinceAges 15–30 - NCT06514755Recruiting
Nerve block before artery treatment for knee pain
This study tests a two-step procedure for long-term knee pain that hasn't improved with other treatments. First, the nerves around the knee are numbed, and then the small arteries feeding the painful area are blocked. The goal is to see if doing the nerve treatment before the artery treatment works better for reducing pain.
ZagazigAges 18–80 - NCT06515691Recruiting
Nerve block for pain after weight loss surgery
This study tests a nerve block (an injection near the nerves) to see if it helps reduce pain after laparoscopic sleeve gastrectomy. The block is called a modified thoracoabdominal nerve plane block, and it may lead to better pain control and recovery.
Istanbul, BagcilarAges 18–65 - NCT06515925Recruiting
Virtual group program for managing chronic pain
This study tests a virtual group program that combines medical care with integrative approaches like mindfulness and gentle movement to help adults manage chronic musculoskeletal pain.
Malden, MassachusettsAges 18 years+ - NCT06517069Recruiting
Acupuncture plus medication for pain after gynecologic surgery
This study tests whether adding a type of acupuncture (TEAS) to pain medication can better control pain after laparoscopic gynecologic surgery. It aims to improve recovery and comfort.
Yangzhou, JiangsuAges 18–65
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.