Clinical trials
Pain clinical trials
Below are recruiting pain clinical trials, each written for real people, not researchers. We’re tracking 3,263 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06962709Enrolling by invitation
Warmed lidocaine for less pain during eye injections
This trial tests whether warming the numbing medicine (lidocaine) before an eye injection reduces pain. If you're already getting an eye injection for any reason, you may be able to join.
Columbia, MissouriAges Any age - NCT06957639Enrolling by invitation
Physiotherapy for chronic neck pain
This trial tests a physiotherapy program for people with neck pain lasting 3 months or longer. The goal is to see if it helps reduce pain and improve daily function.
Yozgat, YozgatAges 18–64 - NCT06956508Enrolling by invitation
VR therapy to prevent phantom limb pain after amputation
This study tests whether using virtual reality (VR) daily in the hospital after a major amputation can help prevent phantom limb pain. You'll use a VR headset to do simple exercises that may keep your brain from sending pain signals to the missing limb.
Charlotte, North CarolinaAges 13 years+ - NCT06944314Enrolling by invitation
Doctors' views on pain during flexible cystoscopy with local anesthetic
This trial asks doctors to rate how much pain they think male patients feel during a minimally invasive bladder exam. It aims to see if doctors' estimates of pain are accurate.
Istanbul, IstanbulAges 18 years+ - NCT06865378Enrolling by invitation
Breathing gas and nausea after hysterectomy study
This study looks at whether levels of carbon dioxide in your breath and blood flow measurements during surgery can help predict nausea, vomiting, or pain after a hysterectomy. It may help doctors better manage your recovery.
IstanbulAges 20–65 - NCT06849466Enrolling by invitationPhase 4
Perioperative dexmedetomidine for chronic pain after lung surgery
This study tests whether giving the medication dexmedetomidine during and after surgery can prevent long-term pain after a thoracoscopic lung resection. If you are scheduled for this type of lung surgery, you may be able to join and help see if this drug makes recovery less painful over time.
Beijing, Beijing MunicipalityAges 18–80 - NCT06829030Enrolling by invitationPhase 1/Phase 2
Comparing two injections for low back pain relief
This trial compares two types of injections—one standard anti-inflammatory drug and one simple sugar water solution—to see which works better for treating low back pain in an emergency setting. If you are an adult between 18 and 55 with isolated low back pain, this study may help find a more effective pain treatment.
AksarayAges 18–55 - NCT06822764Enrolling by invitation
Thinking about pain intensity
This study looks at how people think about and rate their own pain. You may be able to join if you have had muscle or bone pain for at least 3 months, in more than one area, and that pain varies in intensity.
Columbia, MissouriAges 18 years+ - NCT06808386Enrolling by invitation
How often should you train for knee pain relief?
This study looks at how different training frequencies affect knee pain recovery. It may help active adults who have had front knee pain for at least three months.
São Paulo, São PauloAges 18–40 - NCT06807229Enrolling by invitation
Core exercises vs. standard therapy for period-related back pain
This study compares core-strengthening exercises with standard physical therapy to see which works better for easing low back pain during your period. If you have painful cramps that affect your lower back, this trial may help find a treatment that works for you.
Gamasah, Al ManşūrahAges 18–35 - NCT06785363Enrolling by invitation
Pelvic ligament release for postpartum back pain
This study tests a technique to release a tight pelvic ligament that can cause lower back pain after pregnancy. It may help women who recently gave birth and have mechanical back or pelvic pain.
CairoAges 25–30 - NCT06783946Enrolling by invitation
Meditation for pain and anxiety after kidney stone surgery
This study is testing whether guided meditation can help reduce pain, discomfort, and anxiety after a kidney stone removal procedure called ureteroscopy. If you or your child is a teenager or adult scheduled for this surgery, meditation might be a calming tool to try before and after the procedure.
Philadelphia, PennsylvaniaAges 12 years+ - NCT06777862Enrolling by invitation
Neck pain study for long-term relief
This study tests if a new approach can help people with chronic neck pain that has lasted at least 6 months and hasn't been treated in the past year. It aims to improve quality of life by finding better ways to manage pain.
Kırşehir, MerkezAges 18–65 - NCT06716359Enrolling by invitation
Comparing two pain medicines after C-section
This trial compares two pain relievers, hydromorphone and nalbuphine, given through a patient-controlled pump after cesarean section. It aims to find which provides better pain control with fewer side effects.
Wuhan, HubeiAges 20–50 - NCT06689345Enrolling by invitation
Brain stimulation study for chronic pain including post-COVID
This study tests if a non-invasive brain stimulation technique can reduce pain in people with chronic pain conditions like fibromyalgia, headaches, or pain that started after COVID-19. It is looking for healthy people and people with ongoing pain to see if the treatment helps.
Sâo Bernardo Do Campo, São PauloAges 18–64 - NCT06684665Enrolling by invitation
How emotions and social factors affect low back pain
This study looks at how social, psychological, and emotional factors might cause problems with movement and daily life in people with back pain. It could help doctors better understand and treat your pain.
Wenzhou, ZhejiangAges 18–75 - NCT06628180Enrolling by invitation
Low-intensity focused ultrasound for chronic pain
This study tests a noninvasive treatment called low-intensity focused ultrasound (LIFU) to help relieve chronic pain. It may be an option if you have had moderate to severe pain for at least 3 months.
Roanoke, VirginiaAges 18–65 - NCT06619171Enrolling by invitation
Teens with chronic pain: a study on distress
This study looks at why some teenagers with long-lasting chronic pain feel more distressed than others. It asks you to fill out a short survey on your phone every day for a period of time, to help researchers understand who is most at risk and when.
BathAges 12–19 - NCT06611722Enrolling by invitation
Study on emotions in chronic hip pain
This study looks at how people feel emotionally when they have long-term hip pain. It aims to understand the differences in mental state among patients with chronic hip pain.
Beijing, Beijing MunicipalityAges 16–65 - NCT06547723Enrolling by invitation
Mindfulness for chronic pain in older adults
This study tests if a program called Mindfulness-Based Stress Reduction (MBSR) helps older adults reduce chronic pain. If you are 65 or older and can read Persian, you may be able to join this study that teaches simple mindfulness techniques to change how you relate to your pain.
Mashhad, Razavi Khorasan ProvinceAges 65–90 - NCT06540456Enrolling by invitation
Capsaicin patch for nerve-related lower back pain
This study tests a medicated patch called Qutenza (capsaicin) to treat chronic lower back pain that involves nerve damage. The patch is placed on the skin to help reduce pain signals.
Summerville, South CarolinaAges 18 years+ - NCT06534593Enrolling by invitation
Physical therapy for low back pain from disc herniation
This trial tests whether physical therapy can help people with a specific type of disc herniation (postero-lateral) by improving pain, stability, walking, and daily function. It may be a good fit if you have low back pain that spreads to your leg or stays in your back.
Islamabad, FederalAges 18–50 - NCT06484192Enrolling by invitationPhase 4
Pain control after lower back fusion surgery
This trial tests a new pain management plan for people having spinal fusion surgery on their lower back. It aims to find the best way to control pain while reducing side effects.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06478628Enrolling by invitation
Insomnia in pain rehabilitation patients
This trial looks at sleep problems in people going through pain rehabilitation. It aims to understand and possibly improve sleep in those with long-lasting pain.
RissaAges 18 years+
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Common questions
- Are there clinical trials for pain?
- Yes. Clin2 currently lists 3,263 recruiting pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.