Clinical trials
Parkinson Disease Dementia clinical trials
Below are recruiting parkinson disease dementia clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07872202Recruiting
Parkinson's rehabilitation and independence study
This study looks at how rehabilitation can help people with Parkinson's disease become more independent and improve their symptoms. It aims to see if specific exercises can make daily tasks easier and improve quality of life.
OlomoucAges 50–80 - NCT07516119Recruiting
Predicting Alzheimer's Risk Before Memory Loss Occurs
This study identifies people at high risk for Alzheimer's disease before symptoms develop, using genetics and digital tools to track brain health over time. If you qualify, you'll help researchers understand who will develop cognitive decline and potentially enable earlier interventions.
San Diego, CaliforniaAges 55 years+ - NCT07297407Recruiting
Prevention program for Parkinson's disease
This study tests a prevention program to see if it can help slow down or stop the early signs of Parkinson's disease. It is for people with a sleep disorder that is linked to a higher risk of Parkinson's, as well as people already diagnosed with early Parkinson's.
KielAges 30–85 - NCT07799402Recruiting
How gut and brain health change with age
This study looks at how the bacteria in your gut are linked to brain health as you age. It includes people with normal memory, mild memory problems, or Alzheimer's disease, and aims to find ways to keep brains healthy as we get older.
Tampa, FloridaAges 18 years+ - NCT06534658Recruiting
Brain Imaging Study for Dementia and MCI
This study uses advanced brain scans (MRI and molecular imaging) to get a clearer picture of dementia and mild cognitive impairment (MCI). It aims to learn more about how the brain changes in these conditions, which could help improve diagnosis and treatment.
Beijing, Beijing MunicipalityAges 50–85 - NCT07777484RecruitingPhase 1
Study of TRB-001 vaccine for Parkinson's disease after prior immunotherapy
This study tests an experimental vaccine called TRB-001 in people with Parkinson's disease who have already received a previous immunotherapy targeting alpha-synuclein. The goal is to see if the vaccine is safe and how it affects the immune system and the disease.
ViennaAges 18 years+ - NCT06505460Recruiting
Brain stimulation for Parkinson's freezing of gait
This study is testing if two brain-stimulation treatments—deep brain stimulation (DBS) or focused ultrasound—can help reduce freezing of gait (a common, frustrating symptom where your feet feel stuck when walking) in people with Parkinson's. Researchers will use brain scans and electrical recordings to understand how these treatments work.
TaichungAges 20–90 - NCT07651319RecruitingPhase 1/Phase 2
IL-2 and Semaglutide Treatment for Alzheimer's Disease
This study tests whether two drugs—IL-2 (an immune-boosting medication) and semaglutide (a diabetes drug that may help brain function)—can slow memory loss in people with Alzheimer's disease. Researchers believe these drugs together might help reduce brain inflammation and protect memory.
Houston, TexasAges 50–86 - NCT07618481Recruiting
Brain Stimulation Study for Alzheimer's Disease
This study tests whether a special type of brain stimulation called 40Hz BCI (brain-computer interface) might help slow memory loss in people with Alzheimer's disease. You would receive daily stimulation sessions at home with help from a caregiver.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT07422857RecruitingPhase 3
A PET scan for detecting signs of Alzheimer's
This trial uses a new type of PET scan to look for specific proteins in the brain that are linked to Alzheimer's disease. It will help doctors see how these proteins relate to cognitive decline and compare scans from people with normal thinking to those with memory problems.
Wuhan, HubeiAges 50 years+ - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07336199Recruiting
Pairing your ratings with DBS programming
This study looks at how your own ratings of your Parkinson's symptoms can help fine-tune your deep brain stimulation (DBS) settings. It is for people with Parkinson's who already have a DBS device that can record brain activity.
MünchenAges 35–80 - NCT04366804Recruiting
Testing two non-movement symptom questionnaires in Parkinson’s
This study checks whether two written questionnaires can reliably measure “non-motor” symptoms in people with Parkinson’s disease. It may help future care by making symptom tracking easier and more accurate.
BesançonAges 30–75 - NCT07040904Recruiting
Mindfulness to help older Latino adults stay mentally sharp
This study tests whether mindfulness training can help older Latino adults stay sharp as they age. Researchers will measure changes in thinking skills and brain health.
St Louis, MissouriAges 65 years+ - NCT06931483Enrolling by invitation
Brain stimulation for Parkinson's motor symptoms
This trial uses a new type of non-invasive brain stimulation to target a deep brain area that controls movement. It aims to improve motor symptoms like stiffness and slowness in people with Parkinson's disease, without needing surgery.
Hefei, AnhuiAges 50–80 - NCT06467539RecruitingPhase 2
New combination treatment for early Alzheimer's or memory loss
This trial tests a new combination treatment (DAOIB and an antioxidant) for people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment can help slow or improve memory and thinking problems.
Kaohsiung CityAges 50–90 - NCT04179695Recruiting
Testing a new communication aid to improve patient-centered care
This study tests a new tool meant to help patients and healthcare teams communicate better and support “patient-centered care.” You may be invited to use the tool and complete study activities during your neurology care visits.
LilleAges 18–90 - NCT02119611Recruiting
Deep brain stimulation for Parkinson’s, dystonia, or tremor
This study tests deep brain stimulation (DBS), a therapy that sends electrical signals to the brain, for movement problems like Parkinson’s disease, dystonia, and essential tremor. It may help people whose symptoms are not controlled enough with medications, or who already have a DBS device and need ongoing management.
Bethesda, MarylandAges 18–100 - NCT06821568Recruiting
Home brain stimulation for memory and walking concerns
This study tests if a gentle brain-stimulation device used at home can help older adults who have both memory worries and slower walking. A study partner will help you use the device.
Roslindale, MassachusettsAges 65–90 - NCT06984757Enrolling by invitation
Brain waves and thinking in Parkinson's disease
This study looks at how brain activity relates to thinking and memory in people with Parkinson's disease, including those with and without cognitive issues, and those with deep brain stimulation. It uses EEG (a non-invasive brain wave recording) and sometimes mild brain stimulation (TMS or tACS) to understand these connections better.
Iowa City, IowaAges 18–99 - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT06850597RecruitingPhase 2
Testing dimethyl fumarate for early Alzheimer's disease
This study tests a drug called dimethyl fumarate to see if it can help people with early Alzheimer's disease. It may slow down memory loss and thinking problems.
Lodz, Łódź VoivodeshipAges 55–90 - NCT05887674Recruiting
Non-drug memory program for early Alzheimer’s and memory loss
This trial studies a non-medication (non-drug) program to improve memory and daily thinking in people with mild cognitive impairment or mild Alzheimer’s disease. It may help by supporting brain function and monitoring symptoms over time.
Shanghai, Shanghai MunicipalityAges 60–90 - NCT06448403Recruiting
Alzheimer's assessment study with brain scans
This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.
Trondheim, TrønderlagAges 65 years+
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Common questions
- Are there clinical trials for parkinson disease dementia?
- Yes. Clin2 currently lists 315 recruiting parkinson disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.