Clinical trials
Parkinson Disease Dementia clinical trials
Below are recruiting parkinson disease dementia clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07410598Recruiting
Testing a new way to use deep brain stimulation at home
This study tests a new type of brain stimulation called patterned stimulation for people with Parkinson's who already have a deep brain stimulation (DBS) device. It aims to see if using this special stimulation at home is safe and comfortable.
Gainesville, FloridaAges 18–80 - NCT07360886Recruiting
Early detection of brain conditions in active drivers
This study looks at how well doctors can spot early signs of certain brain conditions in people who drive. You may join if you have a valid license, are between 18 and 85, and have one of the neurological diagnoses the study is focusing on.
Olomouc, Olomouc RegionAges 18–85 - NCT07355842Recruiting
Can slow brain waves slow Parkinson's?
This study tests whether playing soft sounds during deep sleep can slow down brain changes in people with REM sleep behavior disorder (a condition linked to Parkinson's disease). It is for people who have this sleep disorder or were recently diagnosed with Parkinson's, and are not yet on Parkinson's medications.
Zurich, Canton of ZurichAges Any age - NCT07172295Recruiting
Low-intensity focused ultrasound for hand tremor
This study uses low-intensity focused ultrasound to stimulate a deep brain area and reduce hand tremors. It is for people with Parkinson's disease, essential tremor, or dystonic tremor whose medications don't work well enough.
Hsinchu, Hsinchu CityAges 18–80 - NCT07145190Recruiting
Starting Sublingual Apomorphine for Parkinson's OFF Episodes
This study looks at how patients start and adjust a new medicine (sublingual apomorphine, or SL-APO) for Parkinson's disease OFF episodes. OFF episodes are times when Parkinson's symptoms come back between medicine doses. If you are about to start SL-APO for the first time, this trial may be a good fit.
BerlinAges 18 years+ - NCT07044973Recruiting
Focused ultrasound for Parkinson's disease tremor
This trial uses focused ultrasound to treat tremor and movement problems in Parkinson's disease. It targets a specific brain area without surgery, and may help if your symptoms are worse on one side and not fully controlled by medication.
Beijing, Beijing MunicipalityAges 22 years+ - NCT07038486Recruiting
Testing a digital tool for Parkinson's symptoms
This study tests a digital tool (NMS Assist) to help people with Parkinson's and their caregivers track and manage non-motor symptoms like mood, sleep, and thinking changes. Participation takes place from home using a smartphone or tablet.
Newcastle upon Tyne, Tyne and WearAges 18 years+ - NCT06994728Recruiting
How DBS affects vision and freezing of gait in Parkinson's
This trial looks at how deep brain stimulation (DBS) affects the way you see and move, and how that relates to freezing of gait (when your feet suddenly feel stuck). If you have Parkinson's disease, already have a DBS device, and experience freezing, this study may help researchers understand your symptoms better.
Charleston, South CarolinaAges 18 years+ - NCT06973018Enrolling by invitation
Online cognitive rehab for mild memory problems
This trial tests an online program to help people with mild to moderate cognitive problems after a brain injury or nervous system disease improve their thinking skills. It is for Swedish speakers with internet access.
Stockholm, Stockholm CountyAges 18 years+ - NCT06883266Recruiting
Brain stimulation for movement and fatigue in Parkinson's
This study tests whether a gentle brain stimulation technique called tDCS (transcranial direct current stimulation) can help improve movement and reduce fatigue in people with Parkinson's disease. It's an option for those who are not using deep brain stimulation and don't have certain other health conditions.
Fargo, North DakotaAges Any age - NCT06835595Recruiting
Brain signals as markers of thinking changes in Parkinson's
This study uses a safe, noninvasive brain stimulation method (transcranial magnetic stimulation, or TMS) to look at brain signals related to thinking and memory in people with Parkinson's disease. The goal is to find a better way to measure cognitive changes over time.
Trieste, Friuli Venezia GiuliaAges 18 years+ - NCT06498349Recruiting
DBS for Parkinson's impulse control problems
This trial tests whether deep brain stimulation (DBS) of the subthalamic nucleus can help control impulse control problems (like gambling, overeating, or shopping) in people with Parkinson's disease. It is for patients whose medication-related impulse symptoms are moderate to severe and who are good candidates for DBS surgery.
CologneAges 18–70 - NCT06489483Recruiting
Parkinson's and action regulation study in Dallas
This study looks at how people with Parkinson's disease regulate their actions. It will test your behavior during 'on' periods (when medication is working well) to understand decision-making and movement control.
Dallas, TexasAges 18–80 - NCT06169852Recruiting
Brain signal study during DBS surgery for Parkinson's
This study looks at brain signals during awake deep brain stimulation (DBS) surgery for Parkinson's disease. The goal is to learn how these signals can help guide the placement of electrodes to improve treatment.
Birmingham, AlabamaAges 18–89 - NCT05893186RecruitingEarly Phase 1
Testing DBS settings for walking and balance in Parkinson’s
This early-phase study looks at whether adjusting deep brain stimulation (DBS) can improve posture, walking, and balance in people with Parkinson’s disease. If you already have DBS in place, the trial uses computer-based planning to try different DBS directions and settings to see what helps you most.
Minneapolis, MinnesotaAges 18–89 - NCT04116996Recruiting
Brain stimulation for severe insomnia in Parkinson’s
This trial tests whether stimulating a specific brain area (the globus pallidus) can improve severe insomnia in people who also have Parkinson’s symptoms. You might be considered if your insomnia is very difficult to control and you meet the study’s brain, sleep, and travel requirements.
Jacksonville, FloridaAges 40–80 - NCT05721911Recruiting
Study using brain-cell tests to better understand Parkinson’s risk
This study collects blood and related samples to create a “biobank” and uses lab tests to study genetic risk in Parkinson’s disease and idiopathic REM sleep behavior disorder (RBD). It may help researchers understand why symptoms develop and improve future prevention or treatment approaches.
Milan, ItalyAges 18 years+ - NCT05656586Recruiting
At-home testing for Parkinson’s patients with a DBS device
This study checks how well people can do specific at-home movement tasks using their Medtronic Percept deep brain stimulation (DBS) system. It may help improve how DBS settings are tested and monitored outside the clinic, which could make care safer and more personalized.
Minneapolis, MinnesotaAges Any age - NCT05568199Recruiting
Study of brain imaging in people with DBS for Parkinson’s
This trial is for adults with Parkinson’s who already have a deep brain stimulation (DBS) device and who can have 7‑Tesla (7T) brain imaging. The study uses the MRI pictures to help researchers learn more about Parkinson’s and how the brain changes with treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT05400174Recruiting
How blood pressure changes affect thinking and brain flow in Parkinson’s
This study measures how your blood pressure affects thinking skills and how blood flows in the brain in people with Parkinson’s. It may help researchers understand what blood-pressure changes could mean for cognition in Parkinson’s.
San Diego, CaliforniaAges 50 years+ - NCT04605263Enrolling by invitation
Deep brain stimulation for Parkinson’s walking and falls
This study tests a brain surgery treatment (deep brain stimulation) to help improve gait problems such as freezing of walking, gait instability, or falls in people with Parkinson’s disease. It may help people whose walking symptoms are not well controlled by levodopa (a common Parkinson’s medicine).
Phoenix, ArizonaAges 18–75 - NCT03872102Recruiting
Brain imaging study to track Parkinson-related disease changes
This study uses brain scans and clinical check-ins to better diagnose and predict how Parkinson-related conditions may progress over time. It may help researchers find markers that explain why symptoms change, and could improve future care.
Dallas, TexasAges Any age - NCT03815656Enrolling by invitation
Closed-loop deep brain stimulation for Parkinson’s medication side effects
This study tests a “smart,” closed-loop deep brain stimulation (DBS) system that adjusts stimulation based on your brain signals. It’s designed for people with Parkinson’s who get troubling medication side effects, with the hope of improving symptoms more smoothly.
Durham, North CarolinaAges 18–75 - NCT05457998Enrolling by invitation
Study of Alzheimer’s brain markers using memory testing
This trial looks for signs of Alzheimer’s disease in the brain by using memory and thinking tests, and related study procedures. It may help researchers find better ways to identify Alzheimer’s-related changes earlier.
Providence, Rhode IslandAges 50–80
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Common questions
- Are there clinical trials for parkinson disease dementia?
- Yes. Clin2 currently lists 315 recruiting parkinson disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.