Clinical trials
Parkinson Disease, Idiopathic clinical trials
Below are recruiting parkinson disease, idiopathic clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06438419Recruiting
Brain activity in Parkinson's during movement with DBS
This study records brain activity during movement in people with Parkinson's who have a special deep brain stimulation (DBS) device. It aims to understand how brain rhythms relate to movement, which could improve future treatments.
BordeauxAges 18–75 - NCT05400174Recruiting
How blood pressure changes affect thinking and brain flow in Parkinson’s
This study measures how your blood pressure affects thinking skills and how blood flows in the brain in people with Parkinson’s. It may help researchers understand what blood-pressure changes could mean for cognition in Parkinson’s.
San Diego, CaliforniaAges 50 years+ - NCT07700862Recruiting
Deep brain stimulation for tremor-dominant Parkinson's disease
This trial compares two ways to place electrodes in the brain to reduce tremors. It may help people with Parkinson's disease whose main symptom is shaking.
ShanghaiAges 18–80 - NCT07193303Recruiting
Mental imagery for arm and hand skills in Parkinson's
This study tests if mental imagery exercises can help improve upper body movement in people with Parkinson's disease. It may offer a safe, drug-free way to practice daily tasks.
Kahramanmaraş, OnikişubatAges 40–75 - NCT04116996Recruiting
Brain stimulation for severe insomnia in Parkinson’s
This trial tests whether stimulating a specific brain area (the globus pallidus) can improve severe insomnia in people who also have Parkinson’s symptoms. You might be considered if your insomnia is very difficult to control and you meet the study’s brain, sleep, and travel requirements.
Jacksonville, FloridaAges 40–80 - NCT04681534Recruiting
Testing safer adaptive deep brain stimulation for Parkinson’s
This trial studies an “adaptive” form of deep brain stimulation (DBS) that adjusts based on brain signals, and is mainly done when the DBS battery (IPG) needs replacement or when people are getting DBS for the first time. It aims to improve safety and effectiveness for Parkinson’s symptoms by using recorded brain activity during treatment.
MilanAges Any age - NCT04796506Recruiting
Tracking sleep changes to improve thinking in Parkinson’s
This study looks at whether changes in “slow wave sleep” (a deep sleep stage) match improvements in thinking for people with Parkinson’s. It uses an exercise/recovery-focused approach and checks sleep and thinking scores to see if these changes go together.
Aurora, ColoradoAges 45–100 - NCT05198076Recruiting
TMS follow-up study for balance changes in Parkinson’s
This study looks at how “high-frequency TMS” (a brain stimulation treatment) may change balance in people with Parkinson’s disease over a 6-month follow-up. You may be considered if you have mild to moderate Parkinson’s, have not had TMS before, and are medically stable.
Giza, Ad Doqi, Giza District, Giza GovernorateAges 55–70 - NCT05565443Recruiting
Ultrasound plus GCase treatment for Parkinson’s symptoms
This trial studies whether MR-guided focused ultrasound combined with an enzyme treatment called GCase can improve Parkinson’s disease. It includes people with specific Parkinson’s diagnosis and scan findings, and it may help those with certain genetic or imaging markers.
Toronto, OntarioAges 35–80 - NCT05568199Recruiting
Study of brain imaging in people with DBS for Parkinson’s
This trial is for adults with Parkinson’s who already have a deep brain stimulation (DBS) device and who can have 7‑Tesla (7T) brain imaging. The study uses the MRI pictures to help researchers learn more about Parkinson’s and how the brain changes with treatment.
Minneapolis, MinnesotaAges 21 years+ - NCT05721911Recruiting
Study using brain-cell tests to better understand Parkinson’s risk
This study collects blood and related samples to create a “biobank” and uses lab tests to study genetic risk in Parkinson’s disease and idiopathic REM sleep behavior disorder (RBD). It may help researchers understand why symptoms develop and improve future prevention or treatment approaches.
Milan, ItalyAges 18 years+ - NCT06013956RecruitingPhase 4
Personalized deep brain stimulation for Parkinson's
This study tests a personalized way to adjust deep brain stimulation (DBS) therapy in real time for people with Parkinson's disease. It aims to improve how DBS works by tailoring it to each person's needs.
Cleveland, OhioAges 18–80 - NCT06169852Recruiting
Brain signal study during DBS surgery for Parkinson's
This study looks at brain signals during awake deep brain stimulation (DBS) surgery for Parkinson's disease. The goal is to learn how these signals can help guide the placement of electrodes to improve treatment.
Birmingham, AlabamaAges 18–89 - NCT06409338Recruiting
Ear nerve stimulation for Parkinson's motor symptoms
This study tests whether a gentle nerve stimulation on the ear (taVNS) can improve movement symptoms in Parkinson's disease. It aims to understand how this stimulation affects the brain.
Nanjing, JiangsuAges 40–80 - NCT06608875Recruiting
Personalized stimulation to improve walking and balance
This trial tests a way to help people with Parkinson's disease improve their walking and balance by using personalized stimulation. If you have trouble with walking or balance and are already planning rehab at cereneo, you might be able to join.
Zurich, Canton of ZurichAges 18 years+ - NCT06617884Recruiting
Home balance training for movement disorders
This study tests a home-based walking and balance training program for people with cerebellar ataxia or Parkinson's disease. The training is done at home, so you don't need to travel. The goal is to see if this simple exercise program can improve your walking and balance.
Düsseldorf, North Rhine-WestphaliaAges 18–75 - NCT06835595Recruiting
Brain signals as markers of thinking changes in Parkinson's
This study uses a safe, noninvasive brain stimulation method (transcranial magnetic stimulation, or TMS) to look at brain signals related to thinking and memory in people with Parkinson's disease. The goal is to find a better way to measure cognitive changes over time.
Trieste, Friuli Venezia GiuliaAges 18 years+ - NCT06932692Recruiting
Brain network analysis using 7-Tesla MRI in DBS patients
This study uses advanced brain imaging (7-Tesla MRI and MEG) to understand how deep brain stimulation (DBS) affects brain networks in people with Parkinson's disease or essential tremor. It helps doctors learn how DBS works so they can improve treatment in the future.
Amsterdam, North HollandAges 18 years+ - NCT07044973Recruiting
Focused ultrasound for Parkinson's disease tremor
This trial uses focused ultrasound to treat tremor and movement problems in Parkinson's disease. It targets a specific brain area without surgery, and may help if your symptoms are worse on one side and not fully controlled by medication.
Beijing, Beijing MunicipalityAges 22 years+ - NCT07145190Recruiting
Starting Sublingual Apomorphine for Parkinson's OFF Episodes
This study looks at how patients start and adjust a new medicine (sublingual apomorphine, or SL-APO) for Parkinson's disease OFF episodes. OFF episodes are times when Parkinson's symptoms come back between medicine doses. If you are about to start SL-APO for the first time, this trial may be a good fit.
BerlinAges 18 years+ - NCT07193355Recruiting
Motor imagery training for Parkinson's disease
This trial tests if thinking about movements (motor imagery) can help improve hand function in people with Parkinson's disease. It may offer a non-drug way to manage symptoms.
Kahramanmaraş, OnikişubatAges 40–75 - NCT03371407Recruiting
Study brain movement training in people with Parkinson’s
This study looks at how people with Parkinson’s adapt their movements and how their brain sensorimotor system works. It may help researchers improve understanding of Parkinson’s and refine movement-focused therapies.
MarseilleAges 18 years+ - NCT07635823Recruiting
Adaptive deep brain stimulation for Parkinson's disease
This study tests a new type of deep brain stimulation (DBS)—a surgical treatment that uses electrical pulses to help control Parkinson's symptoms. Unlike standard DBS, this system adapts automatically to your body's needs. You may qualify if you've never had DBS surgery or if you've had it before and are willing to switch to the new device.
Hefei, AnhuiAges 18 years+ - NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100
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Common questions
- Are there clinical trials for parkinson disease, idiopathic?
- Yes. Clin2 currently lists 209 recruiting parkinson disease, idiopathic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson disease, idiopathic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson disease, idiopathic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.