Clinical trials
Parkinsonism clinical trials
Below are recruiting parkinsonism clinical trials, each written for real people, not researchers. We’re tracking 745 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02553525Enrolling by invitation
Testing different stimulation patterns in Parkinson’s, tremor, and MS
This study tests whether changing the “stimulation pattern” in a deep brain stimulator can improve how well symptoms are controlled. If you are already getting (or replacing) a deep brain stimulator, this may help fine-tune the settings for you.
Gainesville, FloridaAges 21–80 - NCT01734122Recruiting
Focused radiation for essential or Parkinson tremor
This trial tests whether precisely targeted radiation to the brain can reduce tremors in people whose symptoms are not controlled enough by medication. It may help those who prefer radiation over deep brain surgery options.
Nashville, TennesseeAges 18 years+ - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT07399496Recruiting
Fast TMS for apathy in Parkinson's disease
This study tests a faster version of TMS (transcranial magnetic stimulation) to see if it can help with apathy—low motivation and lack of interest—in people with Parkinson's disease. You will receive several TMS sessions each day over a short period, and the study team will check if your mood and motivation improve.
Charleston, South CarolinaAges 45–85 - NCT07400731Recruiting
Ear stimulation for Parkinson's symptoms
This study tests whether a device that stimulates the ear can improve Parkinson's symptoms during 'off' periods, when medication wears off. It compares how you feel before and after ear stimulation.
IstanbulAges 44 years+ - NCT07410598Recruiting
Testing a new way to use deep brain stimulation at home
This study tests a new type of brain stimulation called patterned stimulation for people with Parkinson's who already have a deep brain stimulation (DBS) device. It aims to see if using this special stimulation at home is safe and comfortable.
Gainesville, FloridaAges 18–80 - NCT07417280Recruiting
Focused ultrasound for neurological disorders
This trial tests a gentle ultrasound treatment (LIFUS) for people with various brain conditions like epilepsy, tumours, or movement disorders. It aims to see if this non-invasive approach can help where other treatments are being used.
Toronto, OntarioAges 18–85 - NCT07424365Recruiting
Vagus nerve stimulation for thinking skills in health and Parkinson's
This study explores whether vagus nerve stimulation (a gentle electrical pulse that travels through a nerve in your ear) can boost thinking and decision-making skills in healthy people and those with Parkinson's disease. It involves a noninvasive device that stimulates the ear, and you may participate if you meet certain health criteria.
Aurora, ColoradoAges 18–65 - NCT07449117Recruiting
Brain stimulation for language in mild cognitive decline
This study tests a new type of gentle brain stimulation (called temporal interference) to see if it can improve language processing in people with mild cognitive impairment. The stimulation uses electrodes placed on the head and is done while you are in an MRI scanner.
Brno, South MoravianAges 60–80 - NCT07455760Recruiting
Deep brain stimulation and speech sequencing study
This study looks at how deep brain stimulation affects speech in people with Parkinson's disease or essential tremor. It tests whether the stimulation changes the way you say sequences of sounds.
Boston, MassachusettsAges 18 years+ - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07519096Recruiting
Home-Based Fall Prevention Program for Parkinson's Disease
This study tests a fall prevention program designed for people with Parkinson's disease and their care partners. It aims to help reduce falls and improve balance and safety at home.
Beachwood, OhioAges 18 years+ - NCT07533799Recruiting
Swedish BioFINDER Sleep Study: Brain imaging in RBD and Parkinson's
This study examines brain changes in people with REM sleep behavior disorder (acting out dreams during sleep) and early Parkinson's disease using brain imaging scans. Researchers want to understand how sleep problems relate to Parkinson's development and find early warning signs.
MalmöAges 50–100 - NCT07545473Recruiting
Eye Imaging to Detect Brain Disease Markers
This study uses a special camera to photograph the back of your eye in detail. Researchers believe changes in the eye may reflect brain diseases like Alzheimer's or Parkinson's, and this imaging could help detect these conditions earlier.
Melbourne, VictoriaAges 30 years+ - NCT07557706RecruitingPhase 1
Vagus Nerve Stimulation to Improve Heart Function in Parkinson's Disease
This study tests a non-invasive ear-based stimulation technique (taVNS) to help regulate heart function in people with Parkinson's disease. The goal is to see if this gentle stimulation can improve blood pressure and heart rate control.
Birmingham, AlabamaAges 18–80 - NCT07570212Recruiting
Personalized Brain Stimulation for Parkinson's and Similar Disorders
This study tests whether customized transcranial magnetic stimulation (a non-invasive technique that uses magnetic pulses to stimulate brain activity) can help improve symptoms in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The treatment is tailored to each person's brain activity patterns.
Beijing, Beijing MunicipalityAges 30–80 - NCT07574164Recruiting
Brain Stimulation to Reduce Tremor in Parkinson's or Essential Tremor
This trial tests a new type of brain stimulation called closed-loop TMS that automatically adjusts to help reduce tremor in people with Parkinson's disease or essential tremor. The goal is to see if this technology can better control shaking than standard treatments.
Oxford, OxfordshireAges 18 years+ - NCT07580612Recruiting
Home-based AI system for detecting freezing of gait in Parkinson's
This study tests an artificial intelligence system that detects freezing of gait—sudden, involuntary pauses while walking—using sensors you wear at home. The goal is to better understand and eventually help manage this common Parkinson's symptom.
LeuvenAges 18 years+ - NCT07635823Recruiting
Adaptive deep brain stimulation for Parkinson's disease
This study tests a new type of deep brain stimulation (DBS)—a surgical treatment that uses electrical pulses to help control Parkinson's symptoms. Unlike standard DBS, this system adapts automatically to your body's needs. You may qualify if you've never had DBS surgery or if you've had it before and are willing to switch to the new device.
Hefei, AnhuiAges 18 years+ - NCT07640555RecruitingEarly Phase 1
Brain imaging study for Parkinson's and related movement disorders
This research study tests a new type of brain scan (called a PET scan) that may help detect early signs of Parkinson's disease and similar conditions. You'll receive the scan and may have a spinal tap to check for specific protein markers.
New Haven, ConnecticutAges 50–80 - NCT07642908Recruiting
Brain imaging study of Parkinson's disease with LRRK2 gene mutations
This research study uses advanced MRI brain imaging to understand how a specific gene mutation (LRRK2) affects certain brain chemicals in people with Parkinson's disease. The goal is to learn more about how this genetic form of Parkinson's works, which could help develop better treatments.
Ann Arbor, MichiganAges 45 years+ - NCT07595666Enrolling by invitation
New PET scanner versus standard PET for head and neck imaging
This study compares a newer PET/CT scanner (called NeuroEXPLORER) with standard PET/CT scanners for imaging the head and neck region. The goal is to see if the new scanner provides better or clearer images to help diagnose conditions.
Leuven, Vlaams-BrabantAges 4 weeks+ - NCT07586501Enrolling by invitation
Brain Health and Immune System Study in Older Adults
This research study examines how the brain's immune system changes in older adults with memory problems, Parkinson's disease, or normal aging. By understanding these changes, researchers hope to better understand neurodegeneration and develop new treatments.
Yantai, ShandongAges 55–75 - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80
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Common questions
- Are there clinical trials for parkinsonism?
- Yes. Clin2 currently lists 745 recruiting parkinsonism studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinsonism trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinsonism trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.