Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06804642Recruiting
Spinal cord stimulation for Parkinson's walking rehab
This study tests whether a mild electrical stimulation applied to the skin on your lower back (called spinal cord stimulation) can help improve walking and movement in people with Parkinson's disease. It involves some rehabilitation exercises, and the goal is to see if this combination can help you move better.
Louisville, KentuckyAges 18–80 - NCT06753331RecruitingPhase 1/Phase 2
Study of DSP-1083 for Parkinson's disease
This trial tests a new treatment called DSP-1083 for people with Parkinson's disease whose symptoms are not well controlled with standard medications. The study will check if it is safe and if it helps improve movement and daily function.
Lexington, KentuckyAges 40–72 - NCT06701955Recruiting
Reliability of a Fluctuation Scale in Parkinson's
This study tests how consistently a new scale measures 'on-off' fluctuations in Parkinson's disease. If you experience motor fluctuations (times when your symptoms change) and are on stable medication, you may help validate this tool.
GrenobleAges 30–75 - NCT06671600Recruiting
Osteopathic treatment for sleep in Parkinson's disease
This study tests if gentle hands-on treatments (osteopathic manipulative medicine) can improve sleep quality for people with Parkinson's disease. You will wear a Fitbit and a ring to track your sleep, and receive the treatments over several sessions.
Old Westbury, New YorkAges Any age - NCT06634641RecruitingPhase 4
Clozapine and immune function in Parkinson's disease
This trial tests whether clozapine, a medication for psychosis in Parkinson's disease, affects the immune system. It involves regular blood monitoring to help keep patients safe.
SalouëlAges 18 years+ - NCT06565195RecruitingPhase 1
Study of an investigational drug for Parkinson's disease
This study tests an experimental drug called LY3962681 in two groups: healthy volunteers and people with Parkinson's disease. The goal is to see if the drug is safe and how the body handles it, which may lead to future treatments for Parkinson's.
Englewood, ColoradoAges 30–80 - NCT06442033Recruiting
Exercise and genetics to slow Parkinson's
This trial studies whether a regular aerobic cycling program can slow the progression of Parkinson's disease. Researchers will also look at how genetics may affect the benefits of exercise.
Cleveland, OhioAges 18 years+ - NCT06405334Recruiting
Balance and movement study for veterans with Parkinson's
This study looks at how Parkinson's disease affects balance and movement. It may help predict fall risk and improve care. Some participants also have a special brain device to help with movement.
Minneapolis, MinnesotaAges 18 years+ - NCT06402955RecruitingPhase 2
Imaging depression in Parkinson's disease
This study uses brain imaging (PET scans) to understand depression in people with Parkinson's disease. It may also test a depression treatment called ketamine, but the main goal is to see how the brain changes with depression.
New Haven, ConnecticutAges 40–80 - NCT04724941Recruiting
Screening for alpha-synuclein in early Parkinson’s risk
This study looks for changes in a protein called alpha-synuclein in people who may be in the early “prodromal” stage before Parkinson’s symptoms fully appear. It may help researchers find early markers and understand who is more likely to develop Parkinson’s disease.
KielAges 50–99 - NCT06231563RecruitingPhase 2
Ketamine for depression in veterans with Parkinson's
This study tests if ketamine can help treat depression in veterans with Parkinson's disease. It involves several in-person and remote visits, and you will need to avoid certain medications and cannabis for a short time before and during some visits.
San Francisco, CaliforniaAges 40–80 - NCT05518617Recruiting
Imaging study for inherited Parkinson’s using PET, SPECT, and spinal fluid
This trial tests how well special brain scans (PET/SPECT) and spinal fluid tests can show changes in people with inherited (genetic) Parkinson’s. It may help researchers understand what’s happening in the brain and improve how these conditions are measured.
Exeter, DevonAges 25–80 - NCT06154356Recruiting
Watching and imagining movements to help Parkinson's
This study tests whether watching guided movement videos and then imagining those movements can improve walking and movement in people with Parkinson's. It may help if you are in early to moderate stages and don't have serious thinking or health problems.
Karaman, KaramanAges 18–65 - NCT06087926Recruiting
TMS for apathy in Parkinson's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
Chapel Hill, North CarolinaAges 55–80 - NCT06002581Recruiting
Using brain stimulation to slow Parkinson's disease progression
This study tests if a non-invasive brain stimulation technique called rTMS (repetitive Transcranial Magnetic Stimulation) can slow down Parkinson's disease by improving slow-wave sleep. It aims to help people with mild to moderate Parkinson's who are stable on their medication.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT05901818RecruitingPhase 1
Testing a patient’s own stem-cell treatment for Parkinson’s
This Phase 1 study tests whether an “autologous” (from your own body) iNSC-DAP stem-cell treatment is safe and may help symptoms in Parkinson’s disease. It is designed mainly to check safety, while also watching for signs of improvement.
Beijing, Beijing MunicipalityAges 30–85 - NCT05557864Recruiting
Brain scan study for Parkinson’s patients with deep brain stimulators
This study looks at how the location of a deep brain stimulator in Parkinson’s disease affects movement problems. It mainly uses advanced 7T brain imaging to compare brain activity and motor symptoms.
Minneapolis, MinnesotaAges 21–89 - NCT05573542Enrolling by invitation
Study early Parkinson signs in people with IBS
This study looks for early clues of Parkinson’s disease in people who have IBS (irritable bowel syndrome), and compares them with people without IBS. The goal is to understand whether gut symptoms or test results can help spot Parkinson’s earlier.
ÖrebroAges 18–85 - NCT05400499Recruiting
Deep brain stimulation study in Parkinson’s visuomotor function
This trial studies how deep brain stimulation affects hand-eye (visuomotor) coordination in people with Parkinson’s. It may help researchers understand whether the stimulation settings change movement control for daily tasks.
Cleveland, OhioAges Any age - NCT04994015Recruiting
Genetic registry for people with Parkinson’s
This study builds a genetics “registry” of people diagnosed with Parkinson’s disease who agree to genetic testing. Your information may help researchers understand why Parkinson’s happens and improve future treatments.
Birmingham, AlabamaAges 18 years+ - NCT04799470Recruiting
Testing new brain-stimulation patterns for Parkinson’s with DBS
This study tests whether different deep brain stimulation settings can improve symptoms in people with Parkinson’s who already have an implanted DBS system in the subthalamic nucleus (STN). To join, you must already have the specific Medtronic device and show good brain signal and symptom response after surgery.
Omaha, NebraskaAges 19–80 - NCT03025334Recruiting
Brain stimulation study for thinking changes in Parkinson’s
This study tests whether a non-invasive brain stimulation approach (tDCS) can improve thinking and memory in people with Parkinson’s disease. You may be invited because your Parkinson’s is typical and your memory testing shows you do not have dementia.
Winnipeg, ManitobaAges 40 years+ - NCT01682668Recruiting
Deep brain stimulation study for Parkinson movement problems
This study looks at how deep brain stimulation (an implanted brain device) affects Parkinson’s symptoms, especially movement problems like freezing, slowness, or involuntary movements. It may help people whose symptoms are not fully controlled by standard Parkinson medicines.
Paris, PARISAges 18–70 - NCT07809438RecruitingPhase 2
Comparing PET scans for early Parkinson's detection
This study tests two different PET scan resolutions to see which is better at detecting signs of early Parkinson's. It is for people who are already part of a Parkinson's research study and may help improve early diagnosis.
New Haven, ConnecticutAges 18 years+
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.