Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 740 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07625540Recruiting
Targeted Brain Stimulation for Parkinson's Motor and Non-Motor Symptoms
This trial tests a non-invasive brain stimulation technique (using electrical currents applied through the scalp) aimed at the subthalamic nucleus—a brain region involved in movement control—to help reduce both movement-related symptoms (like tremor and stiffness) and non-movement symptoms (like mood and sleep problems) in people with Parkinson's disease.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT07641569Recruiting
Dual-Task Training Methods for Parkinson's Disease
This study compares two different training approaches that combine cognitive (thinking) and physical exercises to help improve balance, walking, and daily functioning in people with Parkinson's disease. The goal is to find which method works better for maintaining independence and preventing falls.
Ankara, KeçiörenAges 40 years+ - NCT07569133Enrolling by invitation
Brain Stimulation to Reduce Depression in Parkinson's Disease
This study tests whether repetitive transcranial magnetic stimulation (rTMS)—a non-invasive brain stimulation technique—can safely reduce depressive symptoms in people with Parkinson's disease. If it works, it could offer a new treatment option for depression that often accompanies Parkinson's.
Daegu, Buk-guAges 40–90 - NCT07375693Enrolling by invitationPhase 2
Melatonin for Parkinson's patients on levodopa
This trial tests if adding melatonin can reduce oxidative stress (a kind of cell damage) in people with mild to moderate Parkinson's disease who are already taking levodopa. It aims to see if melatonin helps protect the brain and improve symptoms.
Dhaka, Dhaka DivisionAges 45–85 - NCT06838741Enrolling by invitation
Virtual reality vs. Otago exercises for Parkinson's
This study tests whether doing virtual reality exercises or the Otago exercise program (a set of balance and strength moves) can help people with Parkinson's disease improve their balance and walking. It may be a good option if you are comfortable with light exercise and technology.
Lahore, Punjab ProvinceAges 50–70 - NCT06641193Enrolling by invitation
rTMS for arm slowness in early Parkinson's
This trial tests a brain stimulation technique called rTMS to see if it can help improve slowness of movement in the arm and hand. It's for people with early-stage Parkinson's whose symptoms started on the left side and whose main problem is moving slowly.
Shanghai, ChinaAges 50–75 - NCT05573542Enrolling by invitation
Study early Parkinson signs in people with IBS
This study looks for early clues of Parkinson’s disease in people who have IBS (irritable bowel syndrome), and compares them with people without IBS. The goal is to understand whether gut symptoms or test results can help spot Parkinson’s earlier.
ÖrebroAges 18–85 - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT06688968Recruiting
Music, thinking, and memory in Parkinson's and Alzheimer's
This study looks at how music engagement affects thinking and memory in people with Parkinson's or Alzheimer's disease. It may help researchers understand how music can support brain health as we age.
Montpellier, HéraultAges 60 years+ - NCT04848077Recruiting
Smartphone exercise program for early Parkinson’s patients
This trial tests whether a motivating phone-based exercise plan can help people with early-stage Parkinson’s move more safely and consistently. You may qualify if you can walk on your own, understand Dutch, and are fairly inactive right now.
Nijmegen, GelderlandAges 18 years+ - NCT05205291Recruiting
Imaging inflammation in Parkinson’s using PET/MR scans
This study uses special brain scans (PET/MR) to see inflammation in people with Parkinson’s disease or related conditions. It may help researchers better understand what drives symptoms and how inflammation changes in the brain.
ExeterAges 50–85 - NCT06536348Recruiting
Parkinson's disease database study in Brazil
This study is creating a database of motor and non-motor symptoms in people with Parkinson's disease in Brazil. It aims to better understand the condition by collecting information, and participation involves tests and questionnaires.
Brasília, Federal DistrictAges 18–120 - NCT07610369RecruitingPhase 2
Psilocybin therapy for depression in Parkinson's disease
This study tests whether psilocybin (a psychedelic compound) combined with therapy can reduce depression in people with Parkinson's disease. If you have moderate-to-severe depression and Parkinson's, this trial may offer a new treatment option.
New Haven, ConnecticutAges 40–80 - NCT07337226Recruiting
Vagus nerve stimulation and treadmill training for Parkinson's walking
This study tests whether a mild electrical stimulation on the ear (called taVNS) combined with treadmill walking can improve walking ability in people newly diagnosed with Parkinson's disease. The goal is to see if this combination helps you walk better and more safely.
Roma, RMAges 50–80 - NCT05550714Recruiting
Choosing anesthesia type during deep brain stimulation for Parkinson’s
This study compares different anesthesia choices during deep brain stimulation surgery for Parkinson’s disease, using a technique that guides electrode placement. It may help your care team choose the safest and most comfortable anesthesia approach for surgery.
BeijingAges 50–80 - NCT05895019Recruiting
Propofol’s effects on brain function in Parkinson’s surgery
This study tests how propofol, a common anesthesia medicine, affects brain activity in people with Parkinson’s disease during planned surgery. It also compares them with people without Parkinson’s during similar non-brain, non-heart surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06543563Recruiting
Esketamine for anesthesia during Parkinson's brain surgery
This trial is testing whether a drug called esketamine (related to ketamine) can help make the anesthesia experience better for people with Parkinson's disease who are undergoing a specific brain surgery called bilateral STN-DBS. If you qualify, you would receive esketamine during your procedure to see if it improves outcomes.
Beijing, Beijing MunicipalityAges 50–80 - NCT06598878Recruiting
AR-assisted walking training for Parkinson's
This trial tests walking training with augmented reality (AR) goggles to help with movement in Parkinson's disease. It may help improve your gait and balance.
TaoyuanAges 20 years+ - NCT06993571Recruiting
Brain stimulation for Parkinson's tremor
This study uses mild electrical stimulation on the brain to see if it can reduce hand tremors in people with Parkinson's disease. It's a non-invasive treatment option that may help improve hand control.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07353463Recruiting
Parkinson's and MSA study with biosamples and imaging
This study collects data from people with Parkinson's disease or multiple system atrophy (MSA) to better understand these conditions. You will have blood, saliva, optional spinal fluid tests, and brain scans (MRI, PET/SPECT).
ShanghaiAges Any age - NCT07398157Recruiting
24-hour adaptive deep brain stimulation for Parkinson's
This trial tests a new deep brain stimulation system that adapts in real time to improve symptom control over 24 hours, especially for people with daytime fluctuations or sleep problems despite standard DBS.
San Francisco, CaliforniaAges 18 years+ - NCT07218952Enrolling by invitation
Radiation therapy for Parkinson's disease
This trial tests if a targeted radiation therapy can help people with early-stage Parkinson's disease that affects only one side of the body. It aims to see if this treatment can slow down the disease and improve symptoms.
Rochester, MinnesotaAges 45–70 - NCT05824728RecruitingPhase 2
Levetiracetam for Parkinson’s psychosis with study partner support
This Phase 2 study tests whether AGB101 (levetiracetam) can reduce hallucinations, delusions, or related symptoms in people with Parkinson’s disease psychosis, while checking safety. You and a study partner will help with dosing and regular check-ins, including MRI scans.
Baltimore, MarylandAges 40–85 - NCT04616508Recruiting
Online arm movement training for people with Parkinson’s
This study uses online tasks to look at how people with Parkinson’s control reaching movements. You may benefit by contributing to research that could improve understanding and future treatments for movement problems.
Newark, DelawareAges 18–85
Hear when a new Parkinson’s disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 740 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.