Clinical trials
Parkinson’s disease clinical trials
A movement disorder caused by the loss of dopamine-producing brain cells. We’re tracking 723 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07056361Recruiting
Testing brain stimulation for better movement in tremor and Parkinson's
This study tests whether stimulating specific brain areas (VOP/VIM) during deep brain stimulation surgery can improve movement and muscle control. It includes people with essential tremor or Parkinson's disease who are already scheduled for this surgery.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06815302Recruiting
Improving turning and freezing in Parkinson's disease
This study tests whether a 6-week exercise program can help people with Parkinson's disease who experience freezing of gait. You would exercise three times a week to see if it reduces freezing and improves turning.
Tempe, ArizonaAges 50–80 - NCT02194816Recruiting
Online survey study for people with Parkinson’s or Parkinsonism
This study looks at how changing certain factors over time relates to symptoms in Parkinson’s disease and related conditions. You may help researchers by completing longer online surveys every 6 months for 5 years.
Kenmore, WashingtonAges 19 years+ - NCT06821230Recruiting
Mindfulness for Parkinson's patients and their caregivers
This study tests whether a dyadic mindfulness program can help both people with Parkinson's disease and their caregivers manage negative emotions. You and your care partner would attend sessions together to learn mindfulness techniques.
Hong KongAges 18 years+ - NCT06304285Recruiting
Acupuncture for Parkinson's with chronic appendicitis
This trial tests whether acupuncture can help people with Parkinson's disease who also have chronic appendicitis. It aims to see if treating the appendix inflammation may also improve Parkinson's symptoms.
Hefei, AnhuiAges 40–70 - NCT07514858RecruitingPhase 2
Lu AF28996 for Parkinson's Disease Motor Fluctuations
This trial tests a new medication called Lu AF28996 to help reduce the periods when Parkinson's symptoms worsen throughout the day (called 'OFF times'). If you have motor fluctuations that are predictable and affecting your daily life, this study might help you experience fewer of these difficult periods.
Farmington Hills, MichiganAges 40–85 - NCT07392411Recruiting
AI study of face and speech in Parkinson's disease
This study uses artificial intelligence to analyze facial expressions and speech patterns in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The goal is to find digital markers that may help track the disease.
Beijing, Beijing MunicipalityAges 15–75 - NCT07284342Recruiting
Study on sleep and advanced Parkinson's with foslevodopa/foscarbidopa
This study looks at how a Parkinson's drug delivered under the skin (foslevodopa/foscarbidopa) affects sleep problems in people with advanced Parkinson's. It is a real-world study that follows your usual treatment, no new experimental drug is being tested.
Málaga, AndalusiaAges 18 years+ - NCT06581523Recruiting
Breathing and meditation for Parkinson's wellness
This trial tests a breathing and meditation practice called SKY to see if it helps people with early-stage Parkinson's and their care partners feel better. You and your care partner will practice daily at home using Zoom.
Coral Springs, FloridaAges 18–75 - NCT07488364Recruiting
Understanding frailty in Parkinson's disease
This study looks at why some people with Parkinson's disease become physically frail. It aims to find factors that may help predict or prevent frailty.
Istanbul, TurkeyAges 40–85 - NCT07432958RecruitingPhase 2
Study of AP-472 with levodopa for Parkinson's motor fluctuations
This trial tests an experimental drug called AP-472, taken alongside your regular Parkinson's medications, to see if it can reduce the amount of "OFF" time you experience each day when symptoms return between doses of levodopa.
Little Rock, ArkansasAges 30–80 - NCT07281755Recruiting
Wearable sensors to predict falls in Parkinson's
This study uses small wearable sensors to measure how you walk and move. The goal is to better track Parkinson's symptoms and predict falls, so your care can be more personalized.
Newcastle upon TyneAges 50 years+ - NCT07253376Enrolling by invitation
Study of a cognitive function scale for Parkinson's in Turkish
This study is testing a new rating scale (a set of questions) to measure how well people with Parkinson's disease can handle daily tasks that require thinking skills. It aims to make sure the scale works well in Turkish.
AnkaraAges 40 years+ - NCT05307055Recruiting
Testing brain effects after low-frequency stimulation in Parkinson’s
This study looks at how Parkinson’s disease symptoms and brain thinking (neurocognitive function) may change after low-frequency stimulation from an implanted brain device. It may help researchers understand whether this specific stimulation pattern could improve thinking or brain-related symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT06642519Enrolling by invitation
Brain-computer interface for freezing of gait in Parkinson's
This study tests a brain-computer interface device to help people with Parkinson's disease who experience freezing of gait. The goal is to see if the device can reduce freezing episodes when medication isn't enough.
Toronto, OntarioAges Any age - NCT05626608Recruiting
Directional brain stimulation for Parkinson’s tremor and movement control
This trial tests a continuous electrical brain stimulation device placed in a deep brain area to help Parkinson’s symptoms—especially tremor and trouble with movement. It may help improve daily function and reduce periods when medicine does not work well.
Montpellier, FranceAges 18–70 - NCT05818189Recruiting
Study walking brain signals in Parkinson’s with medication and cues
This study measures brain activity while you walk using a noninvasive light sensor setup. Researchers want to see how Parkinson’s medication and simple “walking cues” change balance and brain signals.
Portland, OregonAges 45–85 - NCT07330258Recruiting
Observing Parkinson's over time in people still having movement symptoms
This study follows people with Parkinson's disease who still have movement symptoms despite taking medication. It aims to understand how the disease changes over time, which could help improve future treatments.
Phoenix, ArizonaAges 45–75 - NCT07720765Recruiting
Using eye scans to study brain diseases
This trial uses a type of eye scan (OCT) to look at the retina in people with brain conditions like multiple sclerosis, Alzheimer's, Parkinson's, or migraines. It aims to see if these scans can help doctors learn more about the disease and monitor it over time.
Milan, MilanoAges 18 years+ - NCT07804615RecruitingPhase 2
Investigational drug for tremor from Parkinson's disease
This study is testing an investigational drug for Parkinson's-related tremor (shaking). It aims to see if the drug can help reduce tremor in people whose symptoms are not fully controlled by current treatment.
Scottsdale, ArizonaAges 18–65 - NCT07441915Recruiting
Sleep Sounds and Brain Training for Parkinson's with Mild Memory Problems
This trial tests whether playing soft sounds during sleep can boost the effects of a computer-based brain training program in people with Parkinson's disease who have mild memory or thinking issues. If you qualify, you'll use a headband that plays tones while you sleep and do brain exercises for several weeks.
Zurich, Canton of ZurichAges 18 years+ - NCT06339398Recruiting
Exercise dose and brain health in Parkinson's
This study looks at how different amounts of physical exercise affect brain chemicals, movement symptoms, and brain connections in people with Parkinson's disease. You would walk and do exercises while researchers track changes over time.
Cassino, FrosinoneAges 30–80 - NCT05897957Enrolling by invitation
Follow-up study for people who received BRT-DA01
This study is for people with Parkinson’s disease who previously took part in an earlier BRT-DA01 trial and finished it (or stopped it). It mainly checks how participants do over time after that earlier treatment.
Orange, CaliforniaAges 50–78 - NCT02760108Recruiting
Parkinson’s Families Project for people with family links
This project is for people age 16 and older who have Parkinson’s (or similar symptoms called parkinsonism). It focuses on people with a family history and/or symptoms that started before age 45, to better understand Parkinson’s in families.
LondonAges 16 years+
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Common questions
- Are there clinical trials for parkinson’s disease?
- Yes. Clin2 currently lists 723 recruiting parkinson’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a parkinson’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a parkinson’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.