Clinical trials
Patient Safety clinical trials
Below are recruiting patient safety clinical trials, each written for real people, not researchers. We’re tracking 1,355 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05933057RecruitingPhase 3
Givinostat for wheelchair-bound boys with Duchenne muscular dystrophy
This Phase 3 trial tests givinostat to see if it can improve safety and functional outcomes in boys with Duchenne muscular dystrophy who cannot walk. You might be a candidate if you meet age, genetic diagnosis, wheelchair-level mobility, and specific arm-strength/respiratory/heart criteria.
LeuvenAges 9–17 - NCT07710690RecruitingPhase 1
Study of NRG-103 injection for recurrent high-grade glioma
This trial tests a new injection called NRG-103 for people whose high-grade glioma (a fast-growing brain tumor) has come back after standard treatments. The goal is to see if it's safe and if it might help shrink the tumor.
ShanghaiAges 18 years+ - NCT06478719RecruitingPhase 1/Phase 2
FB-1603 plus TACE for liver cancer patients
This trial tests a new medicine (FB-1603) given along with standard TACE procedure for people with liver cancer. It aims to see if the combination is safe and works better than TACE alone.
Taipei, TaiwanAges 18–85 - NCT03546309Recruiting
Testing RIC to help children with moyamoya after surgery
This trial studies whether a treatment called RIC (remote ischemic conditioning) is safe and helpful for children with moyamoya disease who undergo revascularization surgery. It aims to improve outcomes after surgery and reduce risk, while carefully tracking safety.
Beijing, Beijing MunicipalityAges Up to 18 years - NCT03850574RecruitingPhase 1/Phase 2
Tuspetinib for relapsed or hard-to-treat AML
This early-phase study tests tuspetinib in people with AML that has come back or did not respond to treatment. The goal is to learn whether it is safe and tolerable, how the drug behaves in the body, and whether it shows signs of benefit.
Birmingham, AlabamaAges 18 years+ - NCT03925194RecruitingPhase 2
Test Anakinra injections under the skin for cystic fibrosis
This Phase 2 study tests whether a medicine called anakinra, given as under-the-skin injections, is safe and may improve lung outcomes in adults with cystic fibrosis. You may be able to join if you meet specific breathing and lab criteria and can follow the study schedule.
Heidelberg, Baden-WurttembergAges 12 years+ - NCT04014374Recruiting
Safety study for stem cell transplant after mogamulizumab
This study tracks safety in adults who had a stem cell transplant after taking mogamulizumab. It looks at outcomes and side effects over time, helping doctors understand risks for future patients.
Milwaukee, WisconsinAges 18 years+ - NCT04443010RecruitingPhase 1/Phase 2
Testing a new protein drug with standard treatment for new glioblastoma
This Phase 1/2 study tests whether adding a drug called L19TNF to standard chemoradiotherapy is safe and may work better than standard treatment alone for newly diagnosed glioblastoma. If you qualify, you would be closely monitored for side effects and treatment response.
ZurichAges 18 years+ - NCT04656184RecruitingPhase 3
Anakinra vs IVIG for kids who don’t respond to first IVIG
This study compares two treatments—anakinra and IVIG—for children with Kawasaki disease who still have fever after their first standard IVIG treatment. It aims to find which option works better and is safer for “IVIG non-responders” who may be at risk for heart complications.
Le Kremlin-Bicêtre, Val De MarneAges 3 months–17 years - NCT04663204RecruitingPhase 2
Sparsentan study for IgA kidney disease in adults
This Phase 2 trial studies whether sparsentan is safe and can slow down kidney damage in adults with IgA nephropathy (IgAN). Participants may receive sparsentan to improve kidney-related measures such as protein in the urine.
Cambridge, EnglandAges 18 years+ - NCT04827810RecruitingPhase 1
IV gamitrinib study for advanced cancers needing new options
This early-phase trial tests how safe IV gamitrinib is and how the body processes it in people with advanced cancers that can’t be controlled by standard treatment. It may also help researchers learn the best dose and whether it has signs of anti-cancer activity.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04855435RecruitingPhase 1
Study drug for advanced melanoma and other solid tumors
This Phase 1 trial studies a new experimental immunotherapy (MBS8) for people with advanced solid tumors, focusing first on safety and early signs of benefit. Depending on your cancer type and past treatments, you may receive MBS8 alone or combined with pembrolizumab.
HerlevAges 18 years+ - NCT04893603Recruiting
TAVR valve test for severe, hard-to-pump heart valve
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
BeijingAges 70 years+ - NCT04929223RecruitingPhase 1
Targeted drug study for metastatic colon or rectal cancer
This Phase 1 study tests targeted cancer treatments in people with metastatic colorectal cancer, using genetic “biomarker” results to match you to the right treatment group. It focuses first on safety, and also looks for early signs the treatment may work in specific tumor subgroups.
Birmingham, AlabamaAges 18 years+ - NCT04959903RecruitingPhase 1/Phase 2
SMART101 after T-cell–depleted bone marrow transplant for blood cancers
This early-phase study tests SMART101 given after a T-cell–depleted (T-cell removed) donor bone marrow transplant. It aims to see if the treatment is safe and can help control certain high-risk blood cancers in children and adults.
New York, New YorkAges Any age - NCT04984512RecruitingPhase 2/Phase 3
Testing mitizodone tablets for major depression symptoms
This trial studies whether mitizodone phosphate tablets can improve symptoms of major depressive disorder (MDD). It also checks the treatment’s safety, including mood and physical health effects.
Dongguan, GuangdongAges 18–65 - NCT05208281RecruitingPhase 2/Phase 3
GNR-055 for Hunter syndrome after standard enzyme treatment
This trial tests the safety and effectiveness of a study medicine called GNR-055 in people with Hunter syndrome (MPS II). It may help researchers learn whether the treatment improves outcomes and how the body handles the medicine.
MoscowAges Any age - NCT05268237RecruitingPhase 1/Phase 2
Testing a diabetes pill under the tongue for type 2 diabetes
This early-phase study tests the safety and side effects of liraglutide taken under the tongue, and looks for early signs it improves blood sugar in people with type 2 diabetes. It may help people who want an alternative way to get this medication, but the main goal is to see how safe and tolerable it is.
Hong KongAges 18–65 - NCT05484908Recruiting
Tested treatment for hepatitis B-related liver cancer after immunotherapy
This trial studies whether the ALSS treatment is safe and effective for people with hepatitis B-related hepatocellular carcinoma who recently received immune checkpoint inhibitors. It may help improve outcomes for certain liver-related complications after immunotherapy, based on how their liver tests look.
Guangzhou, GuangdongAges 18–65 - NCT05518578RecruitingPhase 2
Drug trial for hard-to-control focal epilepsy with brain scar
This Phase 2 trial tests SPN-817 in adults whose seizures are still not well controlled despite trying multiple seizure medicines. It targets people with a specific type of brain finding called focal cortical dysplasia and looks at safety/tolerability and seizure outcomes over several weeks.
Jacksonville, FloridaAges 18–70 - NCT05572632Recruiting
COPD wellness rehab program for safety-net patients
This trial studies a COPD (chronic lung disease) wellness and rehabilitation program for people who get care through the safety-net health system. It may help improve day-to-day outcomes by supporting safer exercise and better COPD management.
San Francisco, CaliforniaAges 40–90 - NCT05629689RecruitingPhase 1
PET scan drug check for people with solid tumors
This Phase 1 study tests whether an investigational PET scan tracer is safe and tolerable when used for PET imaging in people with certain solid cancers. It mainly looks at side effects and how well the scan can be done, not whether it treats cancer.
AmsterdamAges 18 years+ - NCT05641610RecruitingPhase 1/Phase 2
Study drug for adults with hemophilia B who still bleed
This Phase 1/2 study tests ZS801, a gene-related treatment, to see how safe it is and whether it helps prevent bleeding in adults with hemophilia B. You may be considered if you’ve had frequent bleeds or joint problems and meet several lab and health requirements.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05726396RecruitingPhase 2
Microbiome therapy for steroid-resistant immune colitis
This Phase 2 pilot study tests a “restorative microbiota therapy” (RMT) to treat colitis caused by immune checkpoint inhibitors when standard treatments like steroids are not working. It aims to see if this approach is safe and practical, and may improve diarrhea and gut inflammation.
Brainerd, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for patient safety?
- Yes. Clin2 currently lists 1,355 recruiting patient safety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a patient safety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a patient safety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.