Clinical trials
Pediatric Pain clinical trials
Below are recruiting pediatric pain clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07352683Recruiting
Nerve block for kids having belly surgery
This trial tests a nerve block to reduce pain in children aged 1–15 who are having open abdominal surgery. It aims to see if this approach improves recovery.
UppsalaAges 1–15 - NCT06691867Recruiting
Integrative training for sickle cell pain in teens
This study tests an integrative training program designed to help adolescents with sickle cell disease manage their pain better. It combines physical and mental techniques to reduce pain and improve quality of life.
Hartford, ConnecticutAges 12–18 - NCT06781060Recruiting
Nerve stimulation for sciatic nerve injury in children
This trial tests if electrical nerve stimulation can help children aged 3 to 19 who have nerve damage in the leg caused by an injection. The goal is to improve nerve healing and leg function.
Multan, Punjab ProvinceAges 3–19 - NCT07426731Recruiting
Comparing two pain blocks for hypospadias surgery in boys
This trial tests two different ways to numb the area for hypospadias repair surgery in young boys. It aims to find which method works better to manage pain after the operation.
IstanbulAges 1–7 - NCT03838107Recruiting
Tracking changes in pediatric CRPS using study markers
This study looks at how signs in the body change over time in children with CRPS (complex regional pain syndrome). It mainly involves being assessed alongside the usual CRPS care, and often includes MRI checks to better understand the pain course.
Cincinnati, OhioAges 10–17 - NCT07212036Recruiting
Ultrasound for elbow fractures in children
This study uses ultrasound, a sound-wave imaging tool, to diagnose elbow fractures in children. It aims to see if ultrasound works as well as X-rays, so your child might avoid radiation.
Orlando, FloridaAges Up to 18 years - NCT07576985Enrolling by invitation
IV Tylenol for Pain and Agitation After Throat Surgery in Young Children
This study tests whether giving acetaminophen (Tylenol) through an IV (a vein) instead of by mouth helps reduce pain and fussiness after tonsil and adenoid removal in children age 7 and under. The goal is to find better ways to keep children comfortable during recovery.
Cleveland, OhioAges Up to 8 years - NCT07160621Recruiting
Pain management app for teen cancer survivors
This trial tests a culturally adapted mobile app to help teen cancer survivors manage chronic pain and improve daily functioning. It compares the app to standard care to see if it reduces pain interference.
Memphis, TennesseeAges 10–17 - NCT07426796Recruiting
Comparing two pain blocks for pediatric testicle surgery
This trial compares two types of numbing injections for pain after surgery to fix an undescended testicle in young boys. It aims to find which injection works better for comfort during recovery.
IstanbulAges 1–7 - NCT05260320Recruiting
Testing the best anesthesia plan for teens having jaw surgery
This study looks at whether a standardized anesthesia plan works best for kids and teens having Le Fort jaw surgery at Johns Hopkins. If you qualify, the team may use or adjust anesthesia to improve safety and comfort during surgery.
Baltimore, MarylandAges 14 years+ - NCT07145645RecruitingPhase 3
Comparing topical diclofenac to oral ibuprofen for pain from ankle or knee injuries in children
This study compares a topical gel (diclofenac) applied directly to the injury site versus an oral medication (ibuprofen) taken by mouth to see which works better for treating pain from ankle or knee injuries in children. It may offer a way to relieve pain without a pill.
Calgary, AlbertaAges 6–18 - NCT07577154Recruiting
Brain-Monitoring Anesthesia for Pediatric Throat Surgery
This trial tests a special brain-monitoring device (called Conox) during anesthesia for children having their tonsils and adenoids removed. The goal is to help doctors give the right amount of anesthetic medicine by watching your child's brain activity in real time.
KayseriAges 3–12 - NCT07619651Recruiting
Pain relief methods after hypospadias repair in young boys
This trial compares two different numbing techniques to help manage pain after hypospadias surgery (a procedure to correct the urinary opening in boys). The goal is to find which method works better and is safer for young children.
KayseriAges 6 months–7 years - NCT07714785Recruiting
EEG-guided anesthesia for better recovery after tonsillectomy
This study tests whether using brain-wave monitoring (EEG) during anesthesia with sevoflurane can reduce the amount of pain medicine needed after tonsillectomy and improve how smoothly children wake up. It could help your child have a more comfortable recovery.
Santiago, RegiónAges 2–8 - NCT05888038Recruiting
Virtual reality to reduce pain after scoliosis surgery
This trial looks at whether virtual reality can lower pain for children and teens after scoliosis repair surgery, which may also reduce how much opioid pain medicine they need. If you join, you would use a virtual reality experience during the post-operative period.
Staten Island, New YorkAges 7–21 - NCT06464146RecruitingPhase 3
Comparing nose and mouth pain medicines for broken bones in kids
This study compares three different fast-acting pain medicines given through the nose or by mouth to children with a suspected broken arm or leg in the emergency room. The goal is to find which medicine works best for pain relief within the first hour.
Boulogne-BillancourtAges 2–17 - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT07740915Enrolling by invitation
Pain relief after heart surgery in children
This study compares two types of pain blocks for children having heart surgery for the first time. The goal is to see which block provides better pain relief after surgery, which could help your child recover more comfortably.
Diyarbakır, DiyarbakırAges birth–18 years - NCT06819033RecruitingPhase 4
Light therapy for canker sores in children
This study tests whether a special light treatment (photobiomodulation) can help reduce pain from canker sores (aphthous ulcers) in children. It may be a good option for kids who get painful mouth sores during dental visits.
Houston, TexasAges 5–17 - NCT07113080RecruitingPhase 4
Do Lemongrass and Lavender Help Kids With Dental Shots?
This study tests whether smelling lemongrass and lavender scents can help reduce fear and pain when a child gets a numbing shot at the dentist. It is for children ages 7 to 11 who are healthy and have never been to the dentist before.
Cairo, Cairo GovernorateAges 7–11 - NCT06832046Recruiting
Intranasal fentanyl for pain in pediatric emergencies
This study looks back at children who already received fentanyl nasal spray for pain in the emergency department. It aims to see how well this method worked for treating sudden pain in children.
StrasbourgAges 1–17 - NCT06559215RecruitingPhase 2
Pain management with Exparel after knee surgery in teens
This trial is testing a long-acting numbing medicine called Exparel to see how well it controls pain after a specific knee surgery (MPFL reconstruction) in teens and young adults. It may help reduce the need for strong painkillers after the operation.
Frisco, TexasAges 13–21 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT05898529Recruiting
Testing COVID status in children having surgery
This study looks at how COVID-19 infection is handled in children (ages 2–17) who are scheduled for surgery. The goal is to compare testing/safety approaches and see how they may protect pediatric surgical patients.
Surrey, British ColumbiaAges 2–17
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Common questions
- Are there clinical trials for pediatric pain?
- Yes. Clin2 currently lists 54 recruiting pediatric pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pediatric pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pediatric pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.