Clinical trials
Perfusion clinical trials
Below are recruiting perfusion clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06799832Recruiting
Guiding fluid management during major abdominal surgery using a new index
This study tests whether a new tool, the urethral perfusion index, can help doctors better manage fluids during and after major abdominal surgery. It uses standard catheters already in place, so there's no extra device needed.
HamburgAges 45 years+ - NCT07585890Recruiting
Liver Transplant Outcomes With Machine Preservation in Europe
This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.
ViennaAges 18 years+ - NCT06846983Recruiting
Testing a new way to predict numbing success for children's surgery
This trial checks if a simple monitor reading (peripheral perfusion index) can help doctors know if a numbing shot (caudal block) will work well for children having belly or pelvic surgery. It may lead to better pain control during and after surgery.
Cairo, AbbasiaAges 1–5 - NCT06986967Recruiting
Comparing Blood Flow Methods During Aortic Arch Surgery
This study compares two methods of supplying blood to the brain during surgery on the main artery from the heart (aorta) and the aortic arch. It may help determine the safest way to protect the brain during cooling and surgery.
Durham, North CarolinaAges 18 years+ - NCT03622359Recruiting
Imaging blood flow in leg artery disease using a scan
This study uses a special “radiotracer” scan to look at how well blood flows through the arteries in the legs. It may help researchers better understand circulation problems from peripheral artery disease.
Columbus, OhioAges 18 years+ - NCT05893407Recruiting
Ultrasound test of brain blood flow in ICU injury
This trial tests whether a contrast-enhanced ultrasound can measure blood flow in the brain of people admitted to the ICU for a sudden brain injury. It may help doctors better assess brain damage and guide care using a bedside imaging method.
ParisAges 18 years+ - NCT06017973Recruiting
Imaging tests for possible non-convulsive status epilepticus
This trial uses advanced imaging scans (PET-MRI) to help doctors better understand and manage a type of seizure that doesn't cause convulsions. It may help improve diagnosis and treatment for people with this condition.
LeuvenAges 16 years+ - NCT06088758Recruiting
Preserving fatty livers with a machine for transplant
This study tests a new way to preserve donated livers that have extra fat (steatotic livers) using a special machine that keeps the liver healthy outside the body. If successful, it could allow more livers to be used for transplantation, helping people on the waiting list get a transplant sooner.
Boston, MassachusettsAges 18–80 - NCT07699094Recruiting
Predicting blood pressure changes in spinal cord injury
This study uses a simple finger sensor to monitor blood pressure regulation in people with spinal cord injury. It aims to find a new way to predict and manage blood pressure issues.
The Bronx, New YorkAges 18–75 - NCT06371924Recruiting
Machine perfusion for livers from donation after circulatory death
This study tests a new way to preserve donated livers (called machine perfusion) after they are recovered from donors who died from circulatory causes. It aims to see if this method helps the liver work better before transplant.
BirminghamAges 18 years+ - NCT05026060Recruiting
Test for brain blood flow imaging in children with artery disease
This study uses a special MRI method to measure how much blood is reaching the brain in children with certain artery problems. It may help doctors better assess these conditions during routine care and imaging.
ParisAges Up to 18 years - NCT05782543Recruiting
Testing improved kidney repair outside the body during transplant
This trial tests a machine method that keeps a donated kidney working “outside the body” so it may be better repaired before transplant. It is designed for certain first/second kidney transplants using specific donor types and storage methods.
Groningen, Provincie GroningenAges 50–100 - NCT05175885Recruiting
Kidney transplant test using machine perfusion outside the body
This study tests a special way to keep and treat a donated kidney using a machine before it’s transplanted. The goal is to improve transplant outcomes for certain people on the kidney transplant waiting list.
ZaragozaAges 18 years+ - NCT04400084Recruiting
Testing how medicines move across the placenta
This trial studies how certain drugs pass from the mother to the baby through the placenta. You may be able to help researchers understand drug safety and transfer during late pregnancy.
ParisAges 18 years+ - NCT03299179Recruiting
Female hormones and brain blood flow during MRI
This study checks how female hormones may change blood flow in the brain. You may be asked to undergo an MRI scan while hormone levels are assessed.
GhentAges 18–25 - NCT02621645RecruitingPhase 4
Early vs late treatment for twin reversed blood flow
This study compares two timing approaches for treating a rare twin complication called twin reversed arterial perfusion (TRAP). It aims to see whether starting treatment earlier or later leads to better baby outcomes and safety for the mother.
Houston, TexasAges 18 years+ - NCT07532811Recruiting
How Lungs Distribute Air and Blood in Critically Ill Children
This pilot study uses a special belt around the chest to measure how air and blood are distributed in the lungs of children on breathing machines in the intensive care unit. The goal is to better understand lung function in critically ill children.
Bron, FranceAges Up to 12 years - NCT07423936Recruiting
Monitoring brain and organ activity in organ donors
This trial tests special monitors on organ donors after life support is withdrawn, to see how the organs and brain behave. It may help improve organ transplant outcomes.
Vancouver, British ColumbiaAges 19 years+ - NCT07315204Recruiting
Liver viability test during machine perfusion
This trial tests a new way to check if a donated liver is healthy while it is kept on a machine that keeps it alive before transplant. Doctors measure a substance called FMN in the fluid that flows through the liver and in bile. This could help them know how well the liver might work after transplant.
Cleveland, OhioAges 18 years+ - NCT07264790RecruitingPhase 1
Minoxidil for Better Blood Flow in Breast Reconstruction
This trial tests whether applying minoxidil (a hair growth medication) to breast tissue during surgery can improve blood flow to the reconstructed breast. It is for women who are having both breasts removed to prevent cancer and have reconstruction on the same day.
Durham, North CarolinaAges 18 years+ - NCT07150559Recruiting
Arch-clamping under mild cooling for acute aortic dissection
This trial tests a surgical technique called arch-clamping under mild hypothermia (cooling the body slightly during surgery) to treat acute type A aortic dissection. It may help patients who need immediate total aortic arch replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT07651748Enrolling by invitationPhase 1/Phase 2
Testing Secretin to Improve Donated Liver Quality
This trial tests whether adding a hormone called secretin to a machine that preserves donated livers outside the body can improve liver quality and transplant outcomes. You may qualify if you're an adult receiving a standard deceased-donor liver transplant that needs special preservation techniques.
Rotterdam, South HollandAges 18 years+ - NCT07307456RecruitingPhase 2
Toripalimab and BCG for high-risk bladder cancer
This trial tests a combination of two treatments after bladder tumor surgery: a drug called toripalimab (given through a vein) plus BCG therapy (given into the bladder) for people with high-risk non-muscle-invasive bladder cancer. The goal is to see if this combination can help prevent the cancer from coming back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT03685890RecruitingPhase 1/Phase 2
Testing nivolumab for melanoma spread to the limb skin
This trial studies nivolumab, an immune medicine, for melanoma that has spread to the skin along a limb (called in-transit metastases). It’s given after a procedure that delivers higher treatment levels to the affected limb, with the goal of shrinking the melanoma and improving outcomes.
AmsterdamAges 18 years+
Hear when a new Perfusion trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for perfusion?
- Yes. Clin2 currently lists 172 recruiting perfusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perfusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perfusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.