Clinical trials
Perfusion clinical trials
Below are recruiting perfusion clinical trials, each written for real people, not researchers. We’re tracking 169 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07423936Recruiting
Monitoring brain and organ activity in organ donors
This trial tests special monitors on organ donors after life support is withdrawn, to see how the organs and brain behave. It may help improve organ transplant outcomes.
Vancouver, British ColumbiaAges 19 years+ - NCT07364474Recruiting
Immune response to liver perfusion therapy for eye melanoma
This study tests how well the liver responds to a treatment called percutaneous hepatic perfusion with melphalan (chemotherapy delivered directly to the liver) in people with uveal melanoma that has spread to the liver. The goal is to see how the immune system reacts and if the treatment helps control the disease.
Boston, MassachusettsAges 18 years+ - NCT07367113Recruiting
Finger sensor guided fluids for skin health in older ICU patients
This study tests if using a finger sensor to guide fluid therapy can prevent skin failure in older ICU patients with sepsis or shock. It compares usual care to personalized fluid management.
Nantong, JiangsuAges 65 years+ - NCT06860438Recruiting
Using a new monitor to guide blood pressure meds in sepsis
This study looks at a special blood flow monitor (perfusion index) to see if it can help doctors decide when to give blood pressure raising medicines in patients with serious infections. It might help doctors better treat sepsis and septic shock.
CairoAges 18 years+ - NCT07324421Recruiting
Ultrasound vs. CT scan for brain blood flow imaging
This study compares a new ultrasound-based method to a standard CT scan for measuring blood flow in the brain. It is designed for people in the ICU or CCU who are already scheduled for a CT scan and could benefit from a simpler, more portable imaging option.
Montpellier, HeraultAges 18 years+ - NCT07307456RecruitingPhase 2
Toripalimab and BCG for high-risk bladder cancer
This trial tests a combination of two treatments after bladder tumor surgery: a drug called toripalimab (given through a vein) plus BCG therapy (given into the bladder) for people with high-risk non-muscle-invasive bladder cancer. The goal is to see if this combination can help prevent the cancer from coming back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07315204Recruiting
Liver viability test during machine perfusion
This trial tests a new way to check if a donated liver is healthy while it is kept on a machine that keeps it alive before transplant. Doctors measure a substance called FMN in the fluid that flows through the liver and in bile. This could help them know how well the liver might work after transplant.
Cleveland, OhioAges 18 years+ - NCT07264790RecruitingPhase 1
Minoxidil for Better Blood Flow in Breast Reconstruction
This trial tests whether applying minoxidil (a hair growth medication) to breast tissue during surgery can improve blood flow to the reconstructed breast. It is for women who are having both breasts removed to prevent cancer and have reconstruction on the same day.
Durham, North CarolinaAges 18 years+ - NCT07150559Recruiting
Arch-clamping under mild cooling for acute aortic dissection
This trial tests a surgical technique called arch-clamping under mild hypothermia (cooling the body slightly during surgery) to treat acute type A aortic dissection. It may help patients who need immediate total aortic arch replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT07112820Recruiting
Heart imaging test for chest pain without ST elevation
This trial tests if a heart imaging scan (myocardial perfusion) can help doctors better diagnose heart attacks or other conditions in people who come to the hospital with chest pain but without ST elevation on their ECG. It aims to see if the scan adds valuable information before heart catheterization.
Paris, Ilede FranceAges 18 years+ - NCT05724641Recruiting
MRI test of eye blood flow in specific optic nerve conditions
This study uses a special MRI scan to measure blood flow to the eye and check how consistently the results match over time. It may help doctors better assess certain optic nerve problems, especially in people without major cardiovascular risk factors.
Brussels, Brussels CapitalAges 18 years+ - NCT06967675Recruiting
Blood flow monitoring in children under low-flow anesthesia
This trial tests whether a device that measures skin blood flow can help monitor children safely during low-flow anesthesia. It is for children aged 2–12 having non-emergency surgery lasting 1–6 hours.
Istanbul, Merkez MahallesiAges 2–12 - NCT06874296Recruiting
Testing machine perfusion for declined livers to shorten transplant wait time
This trial tests whether using a machine to keep donated livers healthy (normothermic machine perfusion) can allow more people to receive a transplant sooner. It is for patients who are already on the waiting list for a liver and have a moderately severe MELD score (25 or less).
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06865378Enrolling by invitation
Breathing gas and nausea after hysterectomy study
This study looks at whether levels of carbon dioxide in your breath and blood flow measurements during surgery can help predict nausea, vomiting, or pain after a hysterectomy. It may help doctors better manage your recovery.
IstanbulAges 20–65 - NCT06371924Recruiting
Machine perfusion for livers from donation after circulatory death
This study tests a new way to preserve donated livers (called machine perfusion) after they are recovered from donors who died from circulatory causes. It aims to see if this method helps the liver work better before transplant.
BirminghamAges 18 years+ - NCT06245239Recruiting
Measuring pain in young children after surgery
This study looks at whether a non-invasive tool called perfusion index can help doctors measure pain in children under 3 years old after hypospadias repair surgery. This could lead to better pain management for young children who cannot easily describe their pain.
Asyut, Assuit GovernorateAges 1 day–3 years - NCT04400084Recruiting
Testing how medicines move across the placenta
This trial studies how certain drugs pass from the mother to the baby through the placenta. You may be able to help researchers understand drug safety and transfer during late pregnancy.
ParisAges 18 years+ - NCT05026060Recruiting
Test for brain blood flow imaging in children with artery disease
This study uses a special MRI method to measure how much blood is reaching the brain in children with certain artery problems. It may help doctors better assess these conditions during routine care and imaging.
ParisAges Up to 18 years - NCT06088758Recruiting
Preserving fatty livers with a machine for transplant
This study tests a new way to preserve donated livers that have extra fat (steatotic livers) using a special machine that keeps the liver healthy outside the body. If successful, it could allow more livers to be used for transplantation, helping people on the waiting list get a transplant sooner.
Boston, MassachusettsAges 18–80 - NCT05782543Recruiting
Testing improved kidney repair outside the body during transplant
This trial tests a machine method that keeps a donated kidney working “outside the body” so it may be better repaired before transplant. It is designed for certain first/second kidney transplants using specific donor types and storage methods.
Groningen, Provincie GroningenAges 50–100 - NCT05758831RecruitingPhase 3
Rituximab vs ocrelizumab for relapsing multiple sclerosis
This trial compares rituximab and ocrelizumab in people with relapsing-remitting multiple sclerosis (MS) to see which medicine better controls MS activity. It may help reduce future relapses and new MRI lesions.
Lyon, BronAges 18–55 - NCT05175885Recruiting
Kidney transplant test using machine perfusion outside the body
This study tests a special way to keep and treat a donated kidney using a machine before it’s transplanted. The goal is to improve transplant outcomes for certain people on the kidney transplant waiting list.
Zaragoza, ZaragozaAges 18 years+ - NCT04588025Recruiting
MRI study using a special model to measure pancreatic cancer response
This study tests a new, harmless “disposable” setup for MRI scans to measure how pancreatic cancer treatments affect the body. It may help doctors get more accurate MRI measurements, so treatment response can be assessed better.
Columbus, OhioAges 19 years+ - NCT07289646RecruitingPhase 3
Lung perfusion scan to guide radiation planning for lung cancer
This study compares two ways of planning radiation treatment for lung tumors. One method uses a special scan to see which parts of your lungs work best, aiming to protect healthy lung tissue, while the other uses a standard anatomical approach. The goal is to see if the functional approach can reduce side effects and improve outcomes.
Brest, FinistèreAges 18 years+
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Common questions
- Are there clinical trials for perfusion?
- Yes. Clin2 currently lists 169 recruiting perfusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a perfusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a perfusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.