Clinical trials · Ohio
Peripheral Arterial Disease clinical trials in Ohio
We’re tracking 24 recruiting peripheral arterial disease studies with a site in Ohio — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT06182397Recruiting
Drug-coated balloon for leg artery blockages below the knee
This trial tests a special balloon coated with sirolimus (a drug that helps prevent arteries from re-closing) versus a standard balloon for opening blocked arteries below the knee in people with severe leg pain or foot wounds. The goal is to see if the drug-coated balloon works better to keep the artery open longer.
Cincinnati, OhioAges 21 years+ - NCT03622359Recruiting
Imaging blood flow in leg artery disease using a scan
This study uses a special “radiotracer” scan to look at how well blood flows through the arteries in the legs. It may help researchers better understand circulation problems from peripheral artery disease.
Columbus, OhioAges 18 years+ - NCT04228978Recruiting
Lifestyle weight-loss program for people with PAD to stay mobile
This trial tests whether a healthy-lifestyle weight-loss program can help people with peripheral artery disease (PAD) lose weight and prevent worsening mobility. You may be eligible if you have PAD based on specific leg blood-flow test results and a higher body weight.
Columbus, OhioAges 18 years+ - NCT04774159RecruitingPhase 3
Low-dose colchicine to lower risk in leg artery disease
This trial tests whether low-dose colchicine can reduce “residual” risk—future heart and blood-vessel problems—in people with peripheral artery disease (PAD). It targets PAD symptoms and complications like poor blood flow in the legs, even after certain procedures.
Columbus, OhioAges 18 years+ - NCT05628948Recruiting
Donate blood for a heart and metabolism research biobank
This study builds a “biobank,” which is a collection of blood and related samples, to support future research on heart and metabolic (sugar/body-fat) conditions. It may help researchers better understand these diseases and improve future prevention and treatments.
Cleveland, OhioAges 18 years+ - NCT05811364Recruiting
Stent versus bare-metal treatment for blocked leg arteries
This study compares a new balloon-expandable stent to standard bare-metal stenting to treat complex blockages in the iliac arteries (main blood vessels to the legs). It may help people with symptoms like leg pain with walking, pain at rest, or minor tissue injury by improving blood flow and reducing repeat procedures.
Cleveland, OhioAges 18 years+ - NCT05916950Recruiting
Study of a new treatment for blocked leg arteries
This trial studies a device-based treatment approach for people with blocked (narrowed or fully blocked) arteries in the thigh or behind the knee that reduce blood flow to the leg. It may help improve blood flow and walking ability, but you must meet specific artery and imaging requirements.
Fairborn, OhioAges 18 years+ - NCT01904851Recruiting
Registry for leg artery procedures and their outcomes
This study collects information about people who had a procedure to improve blood flow in certain leg arteries. It helps researchers understand which treatments work best and what outcomes to expect.
Cleveland, OhioAges Any age - NCT06315023Enrolling by invitation
A registry study for the DETOUR system
This study is collecting information from people who receive the DETOUR system, a treatment for blocked arteries. The goal is to see how well it works in real-world use.
Cleveland, OhioAges Any age - NCT06687590Recruiting
Serranator POINT FORCE registry for leg and dialysis access
This registry study is following patients whose blocked leg or dialysis access arteries are treated with a special balloon (Serranator) that helps open the vessel. The goal is to see how well the device works in real-world use.
Columbus, OhioAges 18 years+ - NCT06271590Recruiting
Drug-coated balloon for small heart artery blockages
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
Cleveland, OhioAges 18–80 - NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Cleveland, OhioAges 18 years+ - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
Cleveland, OhioAges 18–95 - NCT05868161Recruiting
Registry for patients treated with a thrombectomy device
This registry collects past treatment information from people who had a clot procedure using the Pounce Thrombectomy System. It helps researchers understand how this device is used in real-world care and what outcomes may look like.
Cleveland, OhioAges 18 years+ - NCT06544135Recruiting
Thermal camera study for blood flow in PAD with tissue loss
This study uses a special camera that detects heat to see blood flow in your leg before and after a procedure to open blocked arteries.
Beachwood, OhioAges 18–99 - NCT06777901RecruitingPhase 4
Laser plus balloon vs. balloon alone for leg artery blockages
This study compares using a laser device (Auryon) plus balloon angioplasty versus balloon angioplasty alone to open blocked arteries in the lower leg. The goal is to improve blood flow and reduce pain or heal sores in people with advanced peripheral artery disease.
Cleveland, OhioAges Any age - NCT05908331Recruiting
Balloon treatment test for narrowed stents in heart arteries
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
Cleveland, OhioAges 18–110 - NCT07062471Recruiting
Shockwave balloon treatment for hardened carotid arteries before stenting
This study tests a special balloon that uses sound waves to break up calcium buildup in the carotid artery (the main artery in your neck) before placing a stent. It's for people who are at high risk for traditional surgery and have heavy calcium deposits in their artery.
Cincinnati, OhioAges 18 years+ - NCT06653387Recruiting
Testing a new carotid stent with blood-flow reversal for high-risk patients
This trial tests a new carotid stent system used with a special blood-flow reversal device to treat blocked carotid arteries. It is for people with high-risk conditions who might not be good candidates for traditional open surgery, and aims to see if the stent is safe and effective in preventing strokes.
Cincinnati, OhioAges 18–79 - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Cleveland, OhioAges Any age - NCT07521007RecruitingPhase 2
YN001 treatment for coronary artery disease
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
Cincinnati, OhioAges 18–80 - NCT05618353RecruitingPhase 4
Colchicine before surgery to lower heart and inflammation complications
This trial tests whether taking colchicine around the time of surgery can reduce bad events after surgery in people at higher heart risk. It focuses on helping prevent complications related to inflammation after an operation.
Cleveland, OhioAges 18 years+ - NCT07249346RecruitingPhase 2
Preventing GVHD after stem cell transplant with three drugs
This trial tests a three-drug combination (cyclophosphamide, tacrolimus, and ruxolitinib) to prevent graft-versus-host disease (GVHD) after a stem cell transplant. It is for people with certain blood cancers who have a matched donor and can tolerate high-dose chemotherapy.
Columbus, OhioAges 18 years+ - NCT06615050RecruitingPhase 3
Comparing two drug combinations for stem cell transplant
This trial tests two different combinations of medicines to prevent graft-versus-host disease (when donor cells attack your body) after a stem cell transplant. The goal is to see which approach works better for people with certain blood cancers or lymphomas.
Columbus, OhioAges 18 years+
Peripheral Arterial Disease trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting peripheral arterial disease studies listed above.
- Cleveland Clinic · 9 studies
- University Hospitals Cleveland Medical Center · 7 studies
- The Ohio State University Wexner Medical Center · 5 studies
- The Christ Hospital · 2 studies
- Hatton Research Institution
- Louis Stokes Cleveland VA Medical Center
- Miami Valley Hospital
- Nationwide Children's Hospital
What taking part in a peripheral arterial disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Peripheral Arterial Disease trials in other states
Common questions
- Are there peripheral arterial disease clinical trials in Ohio?
- Yes. We're currently tracking 24 recruiting peripheral arterial disease studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a peripheral arterial disease study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a peripheral arterial disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New peripheral arterial disease studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.