Clinical trials · Massachusetts
Peripheral Arterial Disease clinical trials in Massachusetts
We’re tracking 17 recruiting peripheral arterial disease studies with a site in Massachusetts — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT05811364Recruiting
Stent versus bare-metal treatment for blocked leg arteries
This study compares a new balloon-expandable stent to standard bare-metal stenting to treat complex blockages in the iliac arteries (main blood vessels to the legs). It may help people with symptoms like leg pain with walking, pain at rest, or minor tissue injury by improving blood flow and reducing repeat procedures.
Boston, MassachusettsAges 18 years+ - NCT05916950Recruiting
Study of a new treatment for blocked leg arteries
This trial studies a device-based treatment approach for people with blocked (narrowed or fully blocked) arteries in the thigh or behind the knee that reduce blood flow to the leg. It may help improve blood flow and walking ability, but you must meet specific artery and imaging requirements.
Leominster, MassachusettsAges 18 years+ - NCT06300450Recruiting
Alert test for cholesterol meds in PAD patients
This study tests whether a special alert in your electronic health record can help doctors start the right cholesterol-lowering medication for people with peripheral artery disease (PAD) who are not already on one. The goal is to see if the alert helps get treatment started more often.
Boston, MassachusettsAges 18 years+ - NCT06321575Recruiting
New device for clearing leg artery blockages
This trial tests a new device called the Golazo® Atherectomy System that removes plaque from leg arteries to improve blood flow. It may help people with leg pain when walking or small wounds caused by blocked arteries.
Plymouth, MassachusettsAges 18 years+ - NCT01904851Recruiting
Registry for leg artery procedures and their outcomes
This study collects information about people who had a procedure to improve blood flow in certain leg arteries. It helps researchers understand which treatments work best and what outcomes to expect.
Boston, MassachusettsAges Any age - NCT07613840Recruiting
Personalized Blood Clot Prevention After Leg Artery Surgery
This study tests a personalized approach to prevent blood clots in patients who have had surgery to repair blocked arteries in their legs. Researchers want to find the best blood-thinning medication for each individual to reduce serious complications while keeping you safe.
Salem, MassachusettsAges 18 years+ - NCT06315023Enrolling by invitation
A registry study for the DETOUR system
This study is collecting information from people who receive the DETOUR system, a treatment for blocked arteries. The goal is to see how well it works in real-world use.
Boston, MassachusettsAges Any age - NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Worcester, MassachusettsAges 18 years+ - NCT05313165Recruiting
Stent procedure for poor blood flow in the leg ulcers and gangrene
This trial tests a new minimally invasive procedure (placing a small stent) to improve blood flow to a severely threatened foot or lower leg. It may help people whose ulcers or gangrene are not treatable with standard bypass or other surgeries.
Boston, MassachusettsAges 18–95 - NCT06777901RecruitingPhase 4
Laser plus balloon vs. balloon alone for leg artery blockages
This study compares using a laser device (Auryon) plus balloon angioplasty versus balloon angioplasty alone to open blocked arteries in the lower leg. The goal is to improve blood flow and reduce pain or heal sores in people with advanced peripheral artery disease.
Boston, MassachusettsAges Any age - NCT07161583Recruiting
Advanta VXT and Flixene Graft Registry
This registry follows people who have already received an Advanta VXT or Flixene graft to repair or replace a peripheral artery. It collects information from medical records to see how the grafts perform over time.
Boston, MassachusettsAges 18 years+ - NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Boston, MassachusettsAges 30–60 - NCT05908331Recruiting
Balloon treatment test for narrowed stents in heart arteries
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
Boston, MassachusettsAges 18–110 - NCT07062471Recruiting
Shockwave balloon treatment for hardened carotid arteries before stenting
This study tests a special balloon that uses sound waves to break up calcium buildup in the carotid artery (the main artery in your neck) before placing a stent. It's for people who are at high risk for traditional surgery and have heavy calcium deposits in their artery.
Boston, MassachusettsAges 18 years+ - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Boston, MassachusettsAges Any age - NCT06615050RecruitingPhase 3
Comparing two drug combinations for stem cell transplant
This trial tests two different combinations of medicines to prevent graft-versus-host disease (when donor cells attack your body) after a stem cell transplant. The goal is to see which approach works better for people with certain blood cancers or lymphomas.
Boston, MassachusettsAges 18 years+ - NCT07211035Recruiting
Study of a device to help create a working dialysis access
This study tests a device that widens your vein before creating the connection used for dialysis. The goal is to help the access mature faster and work better for your treatments.
Boston, MassachusettsAges 18 years+
Peripheral Arterial Disease trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting peripheral arterial disease studies listed above.
- Massachusetts General Hospital · 6 studies
- Beth Israel Deaconess Medical Center · 3 studies
- Brigham and Women's Hospital · 2 studies
- University of Massachusetts Chan Medical School · 2 studies
- Vascular Breakthroughs · 2 studies
- Beth Israel Medical Center
- Boston Medical Center
- Dana-Farber Cancer Institute
What taking part in a peripheral arterial disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Peripheral Arterial Disease trials in other states
Common questions
- Are there peripheral arterial disease clinical trials in Massachusetts?
- Yes. We're currently tracking 17 recruiting peripheral arterial disease studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a peripheral arterial disease study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a peripheral arterial disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New peripheral arterial disease studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.