Clinical trials
Phenotype clinical trials
Below are recruiting phenotype clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07138963Recruiting
Gene study in children with congenital muscle weakness
This study looks at how genes affect symptoms in children with congenital myopathies or congenital muscular dystrophies. It may help doctors better understand these conditions.
CairoAges 1–18 - NCT07193797Recruiting
A study on confusion after ICU discharge
This study looks at different kinds of confusion (delirium) that can happen after a serious illness and how that may affect you as you heal outside the ICU. The goal is to understand these patterns better to help future patients.
Shanghai, Shanghai MunicipalityAges 18–100 - NCT07222579RecruitingPhase 2
Study of blinatumomab injection for a rare leukemia type
This trial tests a new way to give blinatumomab (a drug that helps your immune system fight cancer) as a shot under the skin for a rare leukemia called MPAL. It includes three different groups of patients depending on their treatment history.
Morgantown, West VirginiaAges 18 years+ - NCT07312240Recruiting
Biomarkers in ALS: A long-term study
This study is looking for people with ALS to help doctors understand how certain biological markers (biomarkers) change over time. It involves a lumbar puncture (spinal tap) to collect fluid from your spine and regular check-ups.
Milan, LombardyAges 18 years+ - NCT07349056Recruiting
Early effects of jaw surgery on gum health
This trial looks at how jaw surgery affects your gums and supporting tissues over six months. It may help if you have certain jaw misalignments need surgery.
EdirneAges 18–65 - NCT07595094Recruiting
Blood Age Test for Predicting Health and Disease Risk
This study uses a special blood test to calculate your 'biological age' and predict your risk for serious illness, death, and how long you'll live healthy. Researchers want to understand if this test can help doctors catch health problems early.
Nanchang, JiangxiAges 35 years+ - NCT07517510Enrolling by invitationPhase 2
HVA treatment for newly diagnosed mixed-phenotype acute leukemia
This study tests a drug called HVA to treat mixed-phenotype acute leukemia (MPAL), a rare blood cancer that has features of both lymphoblastic and myeloid leukemias. You may qualify if you've just been diagnosed and haven't started strong anti-cancer treatment yet.
Guangzhou, GuangdongAges 18 years+ - NCT07149428Enrolling by invitation
Deep study of smell loss causes using brain scans
This study uses brain imaging and electrical recordings to understand the brain's role in smell loss from any cause—like COVID, sinus problems, or chemotherapy. You may be eligible if you have any degree of smell loss lasting under a year.
Bethesda, MarylandAges 18–99 - NCT03680677Recruiting
Checking frailty to guide treatment in older blood cancer patients
This study checks “frailty” (how strong and able you are to function) to help choose better treatment for people age 60+ with certain blood cancers like acute leukemia or MDS. It may help clinicians tailor care before major treatments like transplant or CAR T-cell therapy.
Philadelphia, PennsylvaniaAges 60 years+ - NCT06280820Enrolling by invitation
A study of heart failure patterns (MAP-HEART)
This study looks at different types of heart failure to understand them better. You may join if you have active heart failure (with symptoms like shortness of breath or swelling) and are willing to participate in research activities.
Baltimore, MarylandAges 18–100 - NCT06361641Recruiting
Study of immune cells in blood cancers
This study looks at immune cells (monocytes) in people with certain blood cancers. Researchers want to understand how these cells behave and change over time. You can join if you are newly diagnosed and haven't started treatment yet.
Angers, Maine et LoireAges 18 years+ - NCT05047354Recruiting
Study cholesterol metabolism in rare genetic conditions
This study looks at body chemistry (cholesterol-related lab findings) and physical features in people with Smith-Lemli-Opitz syndrome and related rare genetic cholesterol disorders. It may help researchers better understand these conditions and how they affect the body.
Bethesda, MarylandAges 1 day–100 years - NCT06489249RecruitingEarly Phase 1
Study on vaping, inflammation, and blood vessel health
This study looks at how vaping (e-cigarettes) might affect inflammation and blood vessel health in young adults. You will be asked to take a drug called salsalate to see if it changes these effects.
Iowa City, IowaAges 18–24 - NCT05400733Recruiting
Study of how your body handles meals in older adults
This study looks at your “meal response”—how your blood sugar and related body processes change after eating. It may help researchers understand different metabolic patterns and how to improve health or treatment strategies for older adults.
College Station, TexasAges 60–80 - NCT06533579RecruitingPhase 1/Phase 2
Gene therapy for CD19-positive blood cancers
This trial tests a new gene therapy treatment for people with certain types of leukemia or lymphoma that have the CD19 marker and have not responded to other treatments. The therapy uses a virus to deliver a gene to target and kill cancer cells.
Duarte, CaliforniaAges 13–90 - NCT06864000Recruiting
Genetic study of a brain condition called CAA
This study looks at the genetic causes of cerebral amyloid angiopathy (CAA), a condition where proteins build up in small brain blood vessels. It aims to better understand the disease and may help guide future treatments.
RouenAges 18–99 - NCT05929365Recruiting
Test genetic marker tracking to find returning colon polyps
This study looks at stool or tissue DNA changes (called mutation analysis) plus colonoscopy findings to detect whether colon polyps come back. It may help catch recurrent colorectal lesions earlier during surveillance after a large polyp was removed.
PragueAges 18–75 - NCT05578742Recruiting
Test breathing support patterns in moderate to severe ARDS
This trial studies how adjusting ventilator settings can better match the lungs’ ability to move air and oxygen in people with moderate to severe ARDS. It may help doctors tailor breathing support for different “lung mechanics” patterns, especially during the first days after intubation.
Angers, Maine et LoireAges 18 years+ - NCT05213572Recruiting
Study of organ health in adults with sickle cell
This observational study looks closely at how major organs (like brain, kidneys, heart, lungs, liver, and joints) are working in adults with sickle cell. It may help researchers understand what changes happen after curative treatments (like transplant or gene therapy) or with ongoing care.
Bethesda, MarylandAges 18–100 - NCT04989751Enrolling by invitation
Study of gene patterns in limb-girdle muscle weakness
This study looks at how specific gene changes relate to the pattern of muscle weakness in people with limb-girdle muscular dystrophy (LGMD). It may help doctors better understand the condition and improve future care.
ShanghaiAges 10 years+ - NCT02447861Recruiting
Study of behavior differences in 3q29 deletion or duplication
This study looks at how brain development and behavior may differ in people with a 3q29 deletion or 3q29 duplication. It may help researchers understand what to expect and how these conditions affect daily life.
Piscataway, New JerseyAges Any age - NCT05383287Recruiting
Study of heart failure with preserved pumping function
This study looks at the different features and patterns of people with heart failure where the heart’s pumping strength is preserved. It may help doctors better understand your type of heart failure and tailor care.
ManchesterAges 18 years+ - NCT04639830Recruiting
Testing how sleep patterns relate to child brain development
This study looks at how a child’s sleep looks on a sleep-monitoring test and how that relates to brain/learning growth over time. It includes some children without known risks and some children with known developmental or learning risks, to better understand sleep’s role.
Bethesda, MarylandAges 6 months–8 years - NCT03632239Enrolling by invitation
Share whole-genome or exome data for research
This trial is about building a large library of genetic test results (whole exome or whole genome sequencing) that researchers can use. You may be eligible if your sequencing data is available and you (or your study contact) can be reached again so researchers can include your information responsibly.
Bethesda, MarylandAges 4–120
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Common questions
- Are there clinical trials for phenotype?
- Yes. Clin2 currently lists 315 recruiting phenotype studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a phenotype trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a phenotype trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.