Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05829317RecruitingPhase 4
Magnesium to prevent new atrial fibrillation in ICU patients
This trial tests whether giving magnesium can lower the chance of developing new irregular heartbeat (atrial fibrillation) in critically ill adults in the ICU. If you are at risk but do not already have this rhythm issue, magnesium may help prevent it.
Hamilton, OntarioAges 18 years+ - NCT05998772Recruiting
How sugar affects Parkinsons symptoms
This study looks at how sugar levels might change the way Parkinsons disease feels. If you have mild to moderate Parkinsons, you may be able to join and help researchers learn more about the role of food in your symptoms.
KielAges 50–80 - NCT06343870RecruitingPhase 3
Hormone implants for menopause after cervical cancer or early menopause
This trial tests hormone implants (estradiol and testosterone) to treat menopause symptoms in women who have had their ovaries and uterus removed due to cervical cancer, or who have early menopause. The implants are placed under the skin and may help with hot flashes, mood, and sexual health.
São Paulo, São PauloAges 18–60 - NCT06345443Enrolling by invitation
Nicotinamide riboside for blood vessel health
This trial tests a nutritional supplement (nicotinamide riboside) to see how it affects blood flow in healthy adults. It may help understand how to support vascular health as we age.
Rochester, MinnesotaAges 35–70 - NCT06340217Recruiting
Washed Microbiota Transplant for Diabetic Stomach Paralysis
This trial tests a new treatment called washed microbiota transplantation for diabetic gastroparesis, a condition where the stomach empties slowly due to diabetes. If you have had diabetes for over a year and struggle with bloating or feeling full quickly, this study may explore whether transplanting healthy gut bacteria can help relieve your symptoms.
Nanjing, JiangsuAges 18–100 - NCT06350630RecruitingPhase 2
Hydroxychloroquine for IgA nephropathy
This trial tests whether hydroxychloroquine can help slow kidney damage in people with IgA nephropathy. You may qualify if you have this kidney disease, are already on two standard medicines (RAAS inhibitors and SGLT2 inhibitors), and have ongoing protein in your urine.
Clermont-FerrandAges 18 years+ - NCT06357702Recruiting
Physical Self-Regulation vs Placebo for Chronic Jaw Pain
This study tests whether a physical self-regulation treatment (like relaxation or biofeedback) can help reduce chronic jaw muscle pain. It compares the treatment to a placebo (inactive) version to see if it works better.
Lexington, KentuckyAges 18 years+ - NCT06340789RecruitingPhase 2
Sodium Benzoate Added to Antipsychotics for Resistant Schizophrenia
This study tests whether adding a supplement called sodium benzoate to your current antipsychotic medication can improve symptoms in schizophrenia that hasn't responded well to standard treatments. Researchers will measure brain chemistry changes and symptom improvement over time.
Chiayi CityAges 20–55 - NCT06358677RecruitingPhase 2
Tretinoin cream to prevent skin rash from EGFR drugs
This study tests whether a topical tretinoin cream can prevent the skin rash often caused by anti-EGFR drugs like panitumumab or cetuximab. It is for people with advanced solid tumors who are about to start one of these treatments.
Salt Lake City, UtahAges 18 years+ - NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT06338553RecruitingEarly Phase 1
GLP-1 drug for early type 1 diabetes
This study tests whether a GLP-1 receptor agonist (a type of medicine that helps control blood sugar and appetite) can improve metabolic health in people with early type 1 diabetes. It may be an option if you have already taken teplizumab to delay the disease or were recently diagnosed with type 1 diabetes.
Nashville, TennesseeAges 12–50 - NCT06357234RecruitingPhase 2
Aprepitant to prevent nausea after child scoliosis surgery
This trial tests if a drug called Aprepitant, given before surgery, can better prevent nausea and vomiting after scoliosis repair in children. It is for children aged 8 to 18 who are having spinal fusion surgery for a certain type of scoliosis.
Halifax, Nova ScotiaAges 8–19 - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT04121468RecruitingPhase 1/Phase 2
Metformin trial for vision nerve recovery in young people with MS
This study tests whether metformin can help “reset” damaged nerve cells in the brain and improve vision-related nerve problems in children and young adults with multiple sclerosis. Participants are assigned to metformin or a comparison treatment in a blinded (not everyone knows which) study.
Toronto, OntarioAges 10–25 - NCT06322212RecruitingEarly Phase 1
Type 2 diabetes and brain blood barrier study
This study tests if a treatment can improve the blood-brain barrier in adults with type 2 diabetes. It uses MRI scans to see changes and may help protect brain function.
Los Angeles, CaliforniaAges 40–65 - NCT06326996RecruitingEarly Phase 1
Thiamine before bypass surgery
This study tests if giving thiamine (vitamin B1) before heart bypass surgery can help people with low thiamine levels. It is designed for patients who are having a specific type of bypass that does not use a heart-lung machine.
Los Angeles, CaliforniaAges 60–80 - NCT06335420Recruiting
Can carrot juice prevent colon polyps from coming back?
This study tests whether drinking carrot juice every day can lower the chance that large colon polyps or early colon cancers will come back. Researchers want to see if the nutrients in carrot juice help protect the lining of the colon.
OdenseAges 18 years+ - NCT06333041RecruitingPhase 2/Phase 3
CBD study for Sanfilippo syndrome
This study tests whether a cannabis-derived medicine called cannabidiol (CBD) can help children with Sanfilippo syndrome, a rare genetic disorder. It may be a good fit for children who have already tried other treatments or whose disease is more advanced.
Torrance, CaliforniaAges 4 years+ - NCT06323837RecruitingPhase 2
Testing mirtazapine for methamphetamine use in people on opioid treatment
This trial tests whether the antidepressant mirtazapine can help reduce methamphetamine use in people who are already receiving medication for opioid use disorder. It aims to see if adding this medication improves outcomes for those struggling with both conditions.
Spokane, WashingtonAges 18 years+ - NCT06328114Enrolling by invitationPhase 2
Brain stimulation for cervical dystonia
This study tests a type of brain stimulation called TMS to see if it can improve neck muscle spasms in people with cervical dystonia. It's for adults who haven't had Botox recently and are not on other treatments.
Durham, North CarolinaAges 18 years+ - NCT06334497RecruitingPhase 3
Combination antiviral therapy for CMV in kidney transplant
This trial tests a combination of two antiviral drugs (letermovir and valganciclovir) to treat CMV infections in kidney transplant recipients. It aims to find a safer, more effective treatment option for people with active CMV after transplant.
ParisAges 18 years+ - NCT06336798RecruitingPhase 2
Pioglitazone for pulmonary hypertension from lung disease
This trial tests if pioglitazone, a medicine used for diabetes, can help people with high blood pressure in their lungs caused by chronic lung disease. The goal is to see if it improves how your cells use energy.
Atlanta, GeorgiaAges 18 years+ - NCT06337838RecruitingPhase 3
Preventing blood loss during surgery in kidney patients
This trial tests two medications, tranexamic acid and desmopressin, to see if they can reduce bleeding during surgery in people with severe kidney disease or on dialysis. The results may help make surgery safer for you.
London, OntarioAges 18 years+ - NCT06321991RecruitingPhase 2
Shrinking palm lumps in Dupuytren disease
This study tests a treatment for people with Dupuytren disease who have a lump (nodule) in their palm but no finger bending yet. It aims to see if the lump can shrink and prevent the disease from getting worse.
Leuven, Vlaams-BrabantAges 18 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.