Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06004882Recruiting
Nerve stimulation vs. steroid injection for chronic knee pain
This study compares two treatments for long-term knee pain: a nerve stimulation device placed near the knee versus a steroid shot into the joint. The goal is to see which works better for pain relief.
Houston, TexasAges 18 years+ - NCT06008197RecruitingPhase 3
A study of finerenone for hospitalized heart failure patients
This trial tests a medication called finerenone to see if it helps people hospitalized for heart failure live longer and have fewer heart-related problems. It may be an option for those with a certain type of heart failure where the heart's pumping strength is mildly reduced or normal.
Birmingham, AlabamaAges 18 years+ - NCT06002633Recruiting
Alcohol effects and brain responses in PTSD
This study explores how people with PTSD respond to alcohol and how their brains handle approach or avoidance situations. You may participate if you drink alcohol occasionally and are between 21 and 60 years old.
Austin, TexasAges 21–60 - NCT06027099RecruitingPhase 3
Testing tizanidine to help reduce opioids after surgery
This study tests whether adding a low-dose muscle relaxant (tizanidine) to your pain plan after surgery can help you safely lower your opioid use. It's for people who have been on long-term opioids and are having surgery at specific hospitals.
Stanford, CaliforniaAges 18–75 - NCT06014424RecruitingPhase 2
CBD medication study for agitation in Alzheimer's
This study tests if a CBD medication can help reduce agitation in people with Alzheimer's disease. It's for adults 55 and older who have significant agitation and mild to moderate dementia.
Calgary, AlbertaAges 55 years+ - NCT06017895Recruiting
Doxepin rinse for severe swallowing pain during throat radiation
This trial tests a medicated mouth rinse (doxepin) to ease severe pain when swallowing, caused by radiation therapy for nasopharyngeal cancer. It aims to help patients who are currently receiving radiation and have mouth or throat sores.
Guangzhou, GuangdongAges 18 years+ - NCT06002477RecruitingEarly Phase 1
Attention study in sickle cell disease
This trial tests a medication to see if it can improve attention in people with sickle cell disease. It may help with thinking and focus.
Nashville, TennesseeAges 55 years+ - NCT06012240RecruitingPhase 3
Testing Upadacitinib for Severe Alopecia Areata
This study tests an oral tablet called upadacitinib for people with severe alopecia areata who have lost at least half of their scalp hair. It aims to see if the drug can safely help hair regrow.
Birmingham, AlabamaAges 12–63 - NCT06006559RecruitingPhase 2
Testing a new dengue treatment (EYU688) in adults
This trial tests a new experimental drug, EYU688, for adults with dengue fever. It aims to see if the drug is safe and effective. You may qualify if you have early dengue symptoms, have tested positive for dengue, and are otherwise healthy.
Manaus, AmazonasAges 18–60 - NCT05986292RecruitingPhase 2
Study of new pain treatments for chronic pain
This study tests new treatments for people with chronic pain that has lasted at least 12 weeks. It aims to find better ways to reduce pain and improve quality of life.
Birmingham, AlabamaAges 18 years+ - NCT05988710RecruitingPhase 4
Low-dose buprenorphine for pain in opioid-naive adults
This study tests a low-dose form of buprenorphine (a medicine for pain) placed inside the cheek. It is designed for people who have never taken opioids before, to see how well it works for pain and how likely it is to be misused.
Nashville, TennesseeAges 18–65 - NCT05991804Recruiting
Spinal cord stimulation to improve arm function after injury
This trial tests a treatment that uses mild electrical stimulation on the upper spine to help improve arm and hand function after a recent spinal cord injury. It is for people who are in the hospital and have injury levels between C1 and C8.
LondonAges 18 years+ - NCT05991700RecruitingPhase 1/Phase 2
Grape Powder to Prevent Irregular Heartbeat After Valve Surgery
This trial tests whether a grape powder supplement (rich in plant compounds called anthocyanins) can help prevent a common heart rhythm problem (atrial fibrillation) after mitral valve repair surgery. It is for people who are scheduled for this surgery and do not have certain heart or health issues.
Ann Arbor, MichiganAges 18–79 - NCT05999240RecruitingPhase 2
Pimavanserin for rigid-compulsive symptoms in autism
This trial tests if the drug pimavanserin can help reduce rigid or repetitive behaviors in people with autism spectrum disorder. It may be an option if you or your child struggle with these symptoms and want to try a new treatment.
Lawrence, KansasAges 12–40 - NCT05988632RecruitingPhase 1/Phase 2
Insulin nasal spray for alcohol use disorder
This trial tests whether a nasal spray with insulin can help people with alcohol use disorder. It may affect how the brain responds to alcohol and reduce drinking.
Providence, Rhode IslandAges 21 years+ - NCT05978414Recruiting
Jaw and Pelvis Connections in Women After Prolapse Surgery
This study looks at how the jaw joint and pelvis may be connected in women who have had surgery for pelvic organ prolapse and also have endometriosis. It aims to find new links that could help guide treatment.
PoznanAges 18–60 - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70 - NCT04789850RecruitingPhase 2
Itacitinib for adults with diffuse systemic sclerosis
This Phase 2 study tests itacitinib, a targeted medicine, to see if it can safely improve diffuse systemic sclerosis (a hardening/tightening of the skin and organ involvement). You may be eligible if you have active disease or it has been present less than 3 years.
AmiensAges 18 years+ - NCT05426044RecruitingPhase 2
Metformin to protect the optic nerve in glaucoma
This study tests whether metformin can slow damage to the optic nerve in people with glaucoma. It uses eye scans and vision tests to look for changes over time, aiming to help preserve sight.
Wong Chuk HangAges 18 years+ - NCT05967299RecruitingPhase 1
IV ZMA001 study in healthy adults
This Phase 1 trial tests how an IV medicine called ZMA001 behaves in healthy people and checks for early safety. It may help future studies of the drug by confirming dosing and effects in people before testing in patients.
Bethesda, MarylandAges 18–60 - NCT05946772RecruitingPhase 2
Cyclosporine for Takotsubo heart weakness in the first day
This trial studies whether cyclosporine, an immune-related medicine, can improve outcomes in Takotsubo syndrome (a temporary heart muscle problem). It aims to start treatment very soon after a heart catheter test to help the heart recover.
Bad NauheimAges 18 years+ - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99 - NCT05961501Enrolling by invitationPhase 2/Phase 3
CBD and CBN for long-lasting facial pain and muscle headaches
This trial tests whether CBD and CBN can reduce facial pain and headaches caused by muscle-related problems that have lasted more than 3 months. It may help people who have ongoing symptoms find a new treatment option.
WroclawAges 18 years+ - NCT05966649Recruiting
Synbiotics for preventing preterm birth in higher-risk pregnancies
This trial tests whether taking synbiotics (a mix of “good” probiotics and “food” for them) can help lower the chance of going into labor too early. It’s for pregnant people with certain risk factors for preterm birth, and it compares outcomes while you follow the study plan.
Edegem, AntwerpenAges 18 years+
Hear when a new Placebo - Control trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.