Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04160910RecruitingPhase 2
Studying 5HTP to manage asthma symptoms in kids
This Phase 2 study tests whether 5HTP can help regulate asthma in children and teens who have mild to moderate asthma linked to allergies. It may be an option if your symptoms are allergy-related and you can follow study visits and questionnaires.
Indianapolis, IndianaAges 8–18 - NCT04211259RecruitingEarly Phase 1
Loratadine to reduce bone pain during stem cell collection
This early trial studies whether loratadine (an allergy medicine) can reduce bone pain caused by G-CSF, which is used to help your body collect stem cells. If you have multiple myeloma and are preparing for stem cell mobilization, this may make treatment-related bone pain more tolerable.
New Brunswick, New JerseyAges 18 years+ - NCT04165486RecruitingPhase 1
Test drug safety in adults with multiple system atrophy
This Phase 1 study checks how safe a drug called ION464 is, how the body handles it, and how much of the drug reaches the bloodstream in adults with multiple system atrophy (MSA). It may help researchers find a dosing approach for future treatments for MSA.
InnsbruckAges 40–70 - NCT04232917RecruitingPhase 4
Testing a treatment to help clear genital high-risk HPV
This trial studies 2LPAPI® to see if it helps the body clear high-risk HPV infections in the cervix. It may be an option if you have a current HPV infection with mild/early abnormal cervical findings and can complete follow-up for about a year.
BrusselsAges 25–45 - NCT04145258RecruitingPhase 3
Stronger TB treatment for meningitis to reduce deaths
This trial tests if giving a stronger combination of TB drugs for meningitis can save more lives. It's for patients who have been diagnosed with tuberculosis meningitis and have not yet started more than 5 days of TB treatment.
AbidjanAges 15 years+ - NCT04064060RecruitingPhase 3
Long-term safety follow-up for luspatercept study participants
This trial studies the long-term safety of luspatercept (ACE-536) in people who already took part in an earlier luspatercept study. It mainly helps doctors better understand ongoing side effects and overall safety over time.
Los Angeles, CaliforniaAges 18 years+ - NCT04060030RecruitingPhase 2
Leucovorin for young children with autism language difficulties
This Phase 2 study tests whether leucovorin (a vitamin-related medicine) can improve social communication and language in young children with autism. It also looks at safety and whether the results hold while the child stays on their usual therapies and routines.
Phoenix, ArizonaAges 2.5 years–5 years - NCT04105270RecruitingPhase 2
Durvalumab plus chemo with RMT for lung cancer
This Phase 2 trial studies a new treatment plan that combines RMT with durvalumab and chemotherapy in people with untreated advanced lung adenocarcinoma. It aims to improve outcomes by helping the immune system and fighting cancer cells together.
Phoenix, ArizonaAges 18 years+ - NCT04120714Recruiting
tDCS brain stimulation for problematic internet gaming use
This trial tests whether a noninvasive brain stimulation method (tDCS) can help teens or adults reduce problematic internet gaming. It’s designed for people who meet diagnostic criteria for “pathological use of internet gaming.”
DijonAges 12 years+ - NCT04117672RecruitingPhase 2
Test antisecretory treatment in severe brain injury
This Phase 2 study tests an “antisecretory factor” treatment in people with severe traumatic brain injury. It may help by improving harmful processes after injury, but your eligibility depends on specific brain-injury severity and monitoring needs.
LundAges 10–70 - NCT04066192RecruitingPhase 2
Brexpiprazole trial for alcohol use disorder in adults
This study tests whether brexpiprazole can help adults with alcohol use disorder. You must currently not be taking alcohol-focused treatment or alcohol medicines, and you’ll likely complete questionnaires and brain scans.
Aurora, ColoradoAges 21–65 - NCT04059172RecruitingEarly Phase 1
Ibuprofen plus acetaminophen for braces pain
This early study compares braces pain relief using: ibuprofen alone, ibuprofen plus acetaminophen together, or placebo (no active pain medicine). It may help find which approach works best and is safest for people starting orthodontic treatment.
Aurora, ColoradoAges 12–80 - NCT04104659Enrolling by invitation
Tau PET scan study to map brain changes in Alzheimer’s
This study tests a PET scan “tracer” medicine called [18F]MK-6240 to see how tau protein changes show up in the brain. It may help researchers measure disease-related brain changes in people with normal thinking or mild dementia.
St Louis, MissouriAges 18 years+ - NCT04113993RecruitingPhase 4
Bazedoxifene study in women with schizophrenia
This trial tests whether bazedoxifene can help women with schizophrenia who are stable on their current medicines. You may be asked to do questionnaires and thinking (cognitive) tests to see if symptoms or brain-related measures change.
Melbourne, VictoriaAges 18–65 - NCT04031456RecruitingPhase 2/Phase 3
PRP treatment to help ovaries work again in early ovarian failure
This trial studies whether an injection of your own PRP (platelet-rich plasma) can improve how your ovaries work in people with early ovarian failure. If it helps, it may lead to better hormone balance and return of more regular ovulation and periods.
AthensAges 25–39 - NCT04036188RecruitingEarly Phase 1
Vitamin D and triamcinolone for plaque psoriasis
This early study tests whether taking vitamin D together with triamcinolone (a steroid used on skin) works better for plaque psoriasis than a standard approach. It aims to see if the combination helps clear psoriasis plaques and is safe.
Fairborn, OhioAges 18 years+ - NCT03972124RecruitingPhase 2
Cannabis to prevent migraine attacks before they start
This Phase 2 trial tests whether using cannabis can prevent migraine attacks from happening. It specifically looks at people with chronic migraine who have tried and not benefited from other prevention medicines.
Calgary, AlbertaAges 25 years+ - NCT03977493RecruitingPhase 3
Xeomin injections for focal hand muscle spasms
This trial tests incobotulinumtoxinA (Xeomin) injections to reduce focal hand dystonia—unwanted muscle tightening in the hand. You may be able to join whether you’ve had this condition before or have tried similar injections in the past, as long as certain safety rules are met.
BernAges 18 years+ - NCT03970720RecruitingPhase 2
Metoclopramide to improve low-blood-sugar warning in type 1 diabetes
This Phase 2 study tests whether metoclopramide can help people with type 1 diabetes better notice when their blood sugar is getting too low. If low-blood-sugar warning is unreliable for you, this could help improve safety and control.
Lexington, KentuckyAges 20–60 - NCT03947450RecruitingPhase 2
Injection of your own skin cells into below-knee amputation site
This Phase 2 study tests whether injecting a patient’s own fibroblast cells (skin-support cells) into the wound area after a below-knee amputation can help the stump skin heal and work better. It’s intended for people who already have (or are close to having) a prosthetic fitting.
Baltimore, MarylandAges 18–65 - NCT03954899Recruiting
Melatonin test for brain health in older adults
This study tests whether taking 5 mg of melatonin can improve thinking and brain health over time in older adults with early, mild symptoms. You may help researchers learn which brain changes and measures improve with melatonin.
Iowa City, IowaAges 56–85 - NCT03954483Recruiting
Ear test studies brain wave rhythms for adults
This trial measures a specific brain rhythm (theta waves) using sensors placed on or near the ear canal. It’s mainly looking for healthy adults who can safely complete ear, hearing, and balance checks.
Winnipeg, ManitobaAges 18–40 - NCT03951194RecruitingPhase 2/Phase 3
Platelet-rich plasma infusion for perimenopausal women
This trial tests whether infusing a concentration of your own blood platelets into the ovary can help regulate menstrual cycles and improve ovarian function in women going through perimenopause.
AthensAges 40–50 - NCT03983369RecruitingPhase 3
Laser treatment to help prevent painful mouth sores from chemo
This trial tests whether low-level laser therapy (using special light on the mouth) can prevent or reduce mouth sores caused by chemotherapy in children and young adults. It may help you avoid painful inflammation that can affect eating, comfort, and treatment.
Villejuif, Val de MarneAges 4–25
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.