Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,902 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04534556Enrolling by invitation
Wireless nerve stimulation to improve stroke recovery
This study tests a wireless nerve stimulation device placed near the vagus nerve to help people recover after a stroke. It focuses on people with specific remaining arm/hand movement and recovery levels at least 12 months after stroke.
Dallas, TexasAges 22–79 - NCT04218409RecruitingEarly Phase 1
Tests a spray to reduce opioid use and pain
This early trial studies whether Syntocinon can lower pain and help reduce how much opioids people use. It checks safety and the best dose by giving participants the study drug under close medical monitoring.
Gainesville, FloridaAges 21–45 - NCT04388124RecruitingPhase 2
Test drug to block endothelin for hard-to-control blood pressure
This Phase 2 trial tests whether blocking endothelin (using bosentan and related treatments) can improve blood pressure in people with resistant hypertension—high blood pressure that stays high despite multiple medicines. It may help if your blood pressure is still above target even with the right combination of therapy.
RouenAges 18–80 - NCT04432883Recruiting
Brain stimulation to improve speech after stroke aphasia
This trial tests whether targeted mild brain stimulation (tDCS) can improve speech therapy results for people with long-lasting (chronic) aphasia after a stroke. It may help strengthen naming and communication when added to standard speech-language treatment.
Albuquerque, New MexicoAges 25–85 - NCT04479072RecruitingPhase 4
Aspirin for preeclampsia during delivery
This trial tests whether taking aspirin during pregnancy around the time of delivery helps people with preeclampsia. You may be asked to take aspirin as part of a study plan, with monitoring to see how you do.
Chicago, IllinoisAges 18–45 - NCT04395196RecruitingPhase 2
Prenatal choline for pregnancy after alcohol exposure
This trial tests whether taking a choline supplement during pregnancy can reduce harmful effects on the baby when a person drinks heavily while pregnant. It may help support healthier pregnancy and baby outcomes for those who meet the study’s drinking and nutrition criteria.
Cape Town, Western CapeAges 18–45 - NCT04419584RecruitingPhase 2/Phase 3
Modified Qing-Ying decoction for children with eczema
This trial tests a traditional Chinese herbal formula (Modified Qing-Ying Decoction) for children ages 4 to 17 with moderate-to-severe eczema (atopic dermatitis). The study aims to see if this herbal treatment can improve skin dryness, redness, and itching, especially for those with dry, scaly patches.
Hong KongAges 4–17 - NCT04383262RecruitingPhase 2
Fosamprenavir for reflux-related throat inflammation
This Phase 2 study tests whether fosamprenavir can reduce inflammation and enzyme activity in the throat area for people with laryngopharyngeal reflux (LPR). If you still have LPR symptoms despite 3 months of twice-daily reflux medicine, this trial may offer another treatment approach.
Milwaukee, WisconsinAges 18–64 - NCT04482478Recruiting
Edl treatment trial for functional indigestion symptoms
This trial studies whether EDL medicine can improve symptoms of functional dyspepsia (indigestion) and is safe for people with this condition. You may be asked to complete symptom questionnaires and undergo stomach testing to confirm there is no other cause for your symptoms.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT04444440RecruitingPhase 4
Antibiotic prevention after bladder Botox for overactive bladder
This trial studies whether taking an antibiotic around the time of bladder Botox can lower the risk of urinary infections. It’s for women with overactive bladder who tried standard medicines but didn’t get enough relief.
Edmonton, AlbertaAges 18 years+ - NCT04380740RecruitingPhase 2
Longer vs shorter abatacept doses to prevent graft-versus-host disease
This trial tests whether giving abatacept for a longer or shorter time can better prevent graft-versus-host disease (a common complication after a stem cell transplant). If you’re having a planned unrelated donor transplant, the results may help reduce the risk or severity of transplant-related immune problems.
Duarte, CaliforniaAges 2 years+ - NCT04484025Enrolling by invitationPhase 2
Study of an oral drug for hospitalized COVID-19 patients
This trial tests an oral drug called SPI-1005 for people hospitalized with moderate COVID-19. The drug may help reduce inflammation and protect the lungs, and the study will compare it to a placebo (a pill with no active medicine) to see if it helps people recover.
New Haven, ConnecticutAges 18 years+ - NCT04456816RecruitingPhase 2
Drug test for IgA? No—anti-PLA2R positive immune kidney disease
This Phase 2 trial studies AP1189 in people with a specific immune-related kidney disease called iMN and very high urine protein. It aims to see whether the drug is safe and tolerable and if it can reduce protein in the urine.
AarhusAges 18–85 - NCT04319627RecruitingPhase 3
Statins to prevent new blood clots after leg clot or lung clot
This trial tests whether taking a statin (rosuvastatin) after a recent leg blood clot (DVT) and/or lung blood clot (PE) can lower the chance of future venous clots. You might benefit if you’re at risk for more clotting and can take the study medication safely.
Calgary, AlbertaAges 18 years+ - NCT04326426Enrolling by invitationPhase 3
Study of tradipitant for severe or critical COVID-19
This trial tests whether tradipitant can improve outcomes for adults with severe or critical COVID-19, including pneumonia and low oxygen. It may help patients whose lungs are significantly affected and who need careful hospital-level care.
New York, New YorkAges 18–90 - NCT04308278RecruitingPhase 4
Homeopathic treatment for Epstein-Barr virus fatigue
This study tests a homeopathic treatment (2LEBV® and 2LXFS®) for people with Epstein-Barr virus infection who experience long-lasting fatigue and other symptoms. It aims to see if this treatment helps reduce fatigue and improve overall well-being.
Heule, KortrijkAges 12 years+ - NCT04263038RecruitingPhase 4
Watchful waiting versus blood thinners for small lung clots
This trial compares close monitoring (“watch and wait”) versus taking the blood thinner rivaroxaban in people with a small type of lung blood clot. It aims to find out whether low-risk patients can safely avoid or reduce anticoagulation while still staying healthy.
Woluwe-Saint-Lambert, Brussels CapitalAges 18 years+ - NCT04356326RecruitingPhase 3
Aspirin to prevent complications in pregnancy with chronic high blood pressure
This trial studies whether taking acetyl salicylic acid (aspirin) during pregnancy can reduce problems caused by chronic high blood pressure. It focuses on pregnant people already known to have high blood pressure before or early in pregnancy.
BordeauxAges 18 years+ - NCT04374799RecruitingPhase 3
Heparin vs placebo during cardiac catheterization
This trial tests whether giving heparin (a blood thinner) during a specific type of heart procedure is safer and works better than not giving it. It focuses on patients where the blood supply in the hand’s artery connection is functioning properly.
Hamilton, OntarioAges 18 years+ - NCT04356287RecruitingPhase 1/Phase 2
Cord cell treatment for severe systemic sclerosis symptoms
This early-phase study tests whether umbilical cord-derived “cord blood–type” cells can reduce or improve severe systemic sclerosis (a type of hardening/scarring disease of connective tissue). It may help people whose current standard treatments haven’t worked or caused side effects.
Montreal, QuebecAges 18 years+ - NCT04355572Recruiting
Vitamin D replacement study for teens at risk of PCOS
This study looks at how taking vitamin D affects hormone levels and emotional well-being in teen girls who may develop PCOS. If you have low vitamin D and meet PCOS risk criteria, the study may test whether vitamin D helps you feel and function better.
New Haven, ConnecticutAges 13–21 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Birmingham, AlabamaAges 75 years+ - NCT04325958Recruiting
Test how cannabis affects driving in different age groups
This study looks at how smoked cannabis changes driving performance when compared across two age groups. It may help researchers understand safety risks and differences by age.
Toronto, OntarioAges 19–45 - NCT04172532RecruitingPhase 1/Phase 2
New targeted drug with radiation for locally advanced pancreatic cancer
This Phase 1/2 trial tests adding peposertib, a targeted anti-cancer drug, to standard radiation for people with locally advanced pancreatic adenocarcinoma. It aims to improve control of the cancer after initial chemotherapy and determine whether the combo is safe and effective.
Duarte, CaliforniaAges 18 years+
Hear when a new Placebo - Control trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,902 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.