Clinical trials
Placebo - Control clinical trials
Below are recruiting placebo - control clinical trials, each written for real people, not researchers. We’re tracking 3,955 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07453004RecruitingPhase 2
Study of plonmarlimab for frequent gout attacks
This trial tests a new investigational drug called plonmarlimab for people with frequent, painful gout flares who cannot take standard treatments. The goal is to see if it can reduce pain and inflammation from the flare.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06591091RecruitingPhase 2
Clemastine for Depression in Older Adults
This study tests if adding clemastine (an allergy medication) to standard antidepressants can improve brain health and boost treatment response in adults over 60 with depression.
Chicago, IllinoisAges 60 years+ - NCT07310485Enrolling by invitation
Phytoestrogens for premenstrual syndrome in women nearing menopause
This trial tests whether plant-based compounds (phytoestrogens) can help reduce premenstrual syndrome symptoms in women aged 40–55. It also looks at how these supplements affect gene activity.
Amman, Amman GovernorateAges 40–55 - NCT07733089RecruitingPhase 1
Testing a new psoriasis drug for safety and effect
This trial tests a new study drug (ZP9830) to see if it is safe and works well for people with plaque psoriasis. You would receive the treatment for 8 weeks, and the study will check how your skin responds.
Leiden, South HollandAges 18–60 - NCT06569212RecruitingPhase 4
Beta-blocker to reduce heart damage after brain bleed
This trial tests whether a common beta-blocker (metoprolol) can protect the heart from injury and reduce inflammation after a bleed in the brain (subarachnoid hemorrhage). It may help patients recover better after this type of stroke.
Portland, MaineAges 18 years+ - NCT06990711RecruitingPhase 1
Siltuximab for antibody-mediated rejection after lung transplant
This trial tests a drug called siltuximab to see if it can help treat a type of lung rejection called antibody-mediated rejection (AMR) in people who have had a lung transplant. You may be eligible if you are currently hospitalized for AMR and are already planning to receive standard treatments.
St Louis, MissouriAges 18 years+ - NCT06993155RecruitingPhase 2
Leflutrozole for low testosterone and low sperm count
This trial tests a new drug called Leflutrozole to see if it can improve testicular function in men with low testosterone and low sperm count. The goal is to help increase natural hormone levels and sperm production.
North Hollywood, CaliforniaAges 18–49 - NCT07314411Recruiting
Carotenoids for Eye Health in Healthy Adults
This study tests if taking a carotenoid supplement (MacuHealth) can improve or protect retinal health in healthy adults. You might join if you have normal vision and no major eye or health problems.
Forest Grove, OregonAges 18–75 - NCT06529055Enrolling by invitation
Caffeine and nicotine pouch effects on exercise and brain function
This trial tests how caffeine and nicotine pouches affect your body during exercise, including heart function, thinking, and behavior. It looks at short bursts of high-intensity activity in healthy men who already exercise regularly.
Hattiesburg, MississippiAges 21–40 - NCT06002477RecruitingEarly Phase 1
Attention study in sickle cell disease
This trial tests a medication to see if it can improve attention in people with sickle cell disease. It may help with thinking and focus.
Nashville, TennesseeAges 55 years+ - NCT07495813RecruitingPhase 1
Study of RO7763505 in healthy people and stable heart disease
This study tests an experimental drug (RO7763505) in healthy people and people with stable heart disease. It aims to see how safe the drug is and how it works in the body.
GroningenAges 18–75 - NCT06980636RecruitingPhase 4
Shengmai liquid for long covid fatigue trial
This trial tests if a traditional Chinese medicine, Shengmai Liquid, can help reduce fatigue in people with long COVID. It is for adults aged 18 to 75 who feel tired for a long time after a COVID infection.
Beijing, ChinaAges 18–75 - NCT06004882Recruiting
Nerve stimulation vs. steroid injection for chronic knee pain
This study compares two treatments for long-term knee pain: a nerve stimulation device placed near the knee versus a steroid shot into the joint. The goal is to see which works better for pain relief.
Houston, TexasAges 18 years+ - NCT06302491RecruitingPhase 2
Testing AND017 for beta-thalassemia
This trial tests an oral medication called AND017 for people with beta-thalassemia. It aims to see if the drug can safely help reduce the need for blood transfusions or improve hemoglobin levels.
Guangzhou, GuangdongAges 18–65 - NCT06506422RecruitingPhase 2/Phase 3
How empagliflozin may help aging arteries
This study tests if a diabetes medication, empagliflozin, can reduce age-related stiffening of arteries in people without diabetes. If you are between 60 and 80 and have stiff arteries, this trial could help improve your vascular health.
Columbia, MissouriAges 60–80 - NCT07311200RecruitingPhase 2
Study of D-2570 for active lupus
This trial tests a new oral medication called D-2570 for people with active systemic lupus erythematosus (SLE). It aims to see if the drug can help control lupus symptoms while you continue your current stable treatments.
Linfen, JiangxiAges 18–70 - NCT06959758RecruitingPhase 4
Probiotics for childhood constipation
This study tests whether a probiotic supplement (BioKid LR) can help children with functional constipation — a condition where a child has hard, infrequent bowel movements with no other medical cause. The probiotic contains nine different types of good bacteria, including L. reuteri.
AfulaAges 6 months–17 years - NCT06499324RecruitingPhase 3
Surgery plus Botox for large incisional hernia
This trial tests whether adding Botox injections to surgery helps repair large incisional hernias. It may lower the chance of the hernia coming back.
Colombes, FranceAges 18–79 - NCT06480695Recruiting
Exercise and Beetroot Supplement in Post-Menopausal Women
This study tests whether different exercise intensities combined with a beetroot-based nitrate supplement can improve blood vessel health in post-menopausal women who do not currently exercise regularly.
Charlottesville, VirginiaAges 45–75 - NCT07250802RecruitingPhase 3
Long-term study of zasocitinib for children with plaque psoriasis
This trial tests a daily pill (zasocitinib) for children and teens with moderate to severe plaque psoriasis that hasn't been controlled by other treatments. It aims to see if the pill can safely improve skin symptoms over a long period.
Chula Vista, CaliforniaAges 4–17 - NCT07465263RecruitingPhase 3
Study of SYH2053 Injection for High Cholesterol in HeFH
This study tests a new injection called SYH2053 for people with HeFH, a genetic condition that causes very high cholesterol. It looks at whether the injection can safely lower LDL cholesterol when added to standard statin therapy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06432816Recruiting
Nano therapy for menopausal hot flashes and night sweats
This study tests a new nano-therapy to see if it can reduce hot flashes and night sweats in women going through menopause. It may be a good option if you haven't tried other treatments and are looking for a non-hormonal approach.
Toluca, State of MexicoAges 45–55 - NCT06426355Recruiting
NMN supplement for IVF in women with low ovarian reserve
This study tests whether a supplement called NMN can improve pregnancy outcomes for women with low ovarian reserve who are undergoing IVF or ICSI. It's designed for women who have been told they have a low egg supply and are looking for options to increase their chances.
Beijing, Beijing MunicipalityAges 20–40 - NCT06414005RecruitingPhase 2/Phase 3
TPX-115 injection for partial-thickness rotator cuff tear
This trial tests an injection called TPX-115 for people with a partial-thickness rotator cuff tear (a shoulder tendon injury that doesn't go all the way through). It may help reduce pain and improve movement if you've had shoulder problems for more than 3 months despite other treatments.
Seongnam-si, Gyeonggi-doAges 19 years+
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Common questions
- Are there clinical trials for placebo - control?
- Yes. Clin2 currently lists 3,955 recruiting placebo - control studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo - control trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo - control trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.