Clinical trials
Placebo clinical trials
Below are recruiting placebo clinical trials, each written for real people, not researchers. We’re tracking 5,240 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06340633RecruitingPhase 2
Testing SPI-1005 with cochlear implant surgery
This trial tests an oral medication, SPI-1005, given to adults receiving a cochlear implant to see if it improves hearing outcomes. It may help people with moderate to profound hearing loss who are scheduled for implant surgery.
Iowa City, IowaAges 18 years+ - NCT06340789RecruitingPhase 2
Sodium Benzoate Added to Antipsychotics for Resistant Schizophrenia
This study tests whether adding a supplement called sodium benzoate to your current antipsychotic medication can improve symptoms in schizophrenia that hasn't responded well to standard treatments. Researchers will measure brain chemistry changes and symptom improvement over time.
Chiayi CityAges 20–55 - NCT06341920Recruiting
BoneFit: exercise before hip or knee replacement
This trial tests a pre-surgery exercise program called BoneFit for people waiting at least 6 months for a hip or knee replacement. The goal is to see if getting stronger before surgery helps recovery.
HullAges 18–75 - NCT06344260RecruitingPhase 2
Neural stem cell therapy for ALS: a phase 2 trial
This trial tests whether injecting neural stem cells into the spine can slow down ALS. It is for people with rapidly progressing ALS who have good lung function and a caregiver to help with visits.
San Giovanni Rotondo, FoggiaAges 18–65 - NCT06345703RecruitingPhase 1
First human trial of NS-136 in healthy volunteers
This study tests a new medication called NS-136 for the first time in people. It aims to see how safe and tolerable the drug is when given to healthy adults. If you are generally healthy, you may be able to take part and help researchers learn about this potential new treatment.
Adelaide, South AustraliaAges 18–65 - NCT06345729RecruitingPhase 3
Study of Calderasib and Pembrolizumab for Advanced Lung Cancer
This trial tests a new combination of two drugs (Calderasib and Pembrolizumab) in people with a specific type of advanced lung cancer (non-small cell lung cancer) that has a KRAS G12C mutation and high PD-L1 levels. It aims to see if this treatment can help shrink or control the cancer.
Bakersfield, CaliforniaAges 18 years+ - NCT06347315Recruiting
Studying a nutritional drink for mild memory loss in older adults
This study tests whether a special drink containing medium-chain triglycerides (MCTs, a type of fat) and B vitamins can help support memory and thinking in older adults with mild cognitive impairment (MCI). You would take the drink daily for 18 months and have regular check-ins including memory tests.
BronAges 60 years+ - NCT06349473RecruitingPhase 1
Study of SR604 in healthy people and those with bleeding disorders
This study tests a new drug called SR604 to see if it is safe and how it works in the body. It is for healthy men and for people with hemophilia A, hemophilia B, or factor VII deficiency who have frequent bleeding or are on preventive treatment.
Glendale, CaliforniaAges 18–60 - NCT06349980RecruitingPhase 2
Study of three drugs for liver cancer not yet treated
This trial is testing a combination of three drugs (HLX10, HLX04, and HLX53) to find the best dose and see if they help people with advanced liver cancer who have not had systemic treatment before. The goal is to shrink tumors and improve survival.
ShanghaiAges 18 years+ - NCT06350630RecruitingPhase 2
Hydroxychloroquine for IgA nephropathy
This trial tests whether hydroxychloroquine can help slow kidney damage in people with IgA nephropathy. You may qualify if you have this kidney disease, are already on two standard medicines (RAAS inhibitors and SGLT2 inhibitors), and have ongoing protein in your urine.
Clermont-FerrandAges 18 years+ - NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT06355310RecruitingPhase 2
Studying an SGLT2 inhibitor for fatty liver in teens
This study tests a medication called empagliflozin (a type of SGLT2 inhibitor) to see if it can help treat fatty liver disease in teenagers and young adults. It may improve liver health and help with weight management.
Chicago, IllinoisAges 16–20 - NCT06355583RecruitingPhase 2
Gut bacteria transplant before stem cell transplant
This trial tests whether giving a transplant of healthy gut bacteria (fecal microbiota transplant) before a stem cell transplant can improve outcomes for people with certain blood cancers or bone marrow disorders.
Birmingham, EnglandAges 18 years+ - NCT06357234RecruitingPhase 2
Aprepitant to prevent nausea after child scoliosis surgery
This trial tests if a drug called Aprepitant, given before surgery, can better prevent nausea and vomiting after scoliosis repair in children. It is for children aged 8 to 18 who are having spinal fusion surgery for a certain type of scoliosis.
Halifax, Nova ScotiaAges 8–19 - NCT06357702Recruiting
Physical Self-Regulation vs Placebo for Chronic Jaw Pain
This study tests whether a physical self-regulation treatment (like relaxation or biofeedback) can help reduce chronic jaw muscle pain. It compares the treatment to a placebo (inactive) version to see if it works better.
Lexington, KentuckyAges 18 years+ - NCT06358677RecruitingPhase 2
Tretinoin cream to prevent skin rash from EGFR drugs
This study tests whether a topical tretinoin cream can prevent the skin rash often caused by anti-EGFR drugs like panitumumab or cetuximab. It is for people with advanced solid tumors who are about to start one of these treatments.
Salt Lake City, UtahAges 18 years+ - NCT06359782RecruitingPhase 2
Testing C1-inhibitor for brain bleed after aneurysm
This trial tests a drug called C1-inhibitor (a protein that calms inflammation) given shortly after a bleeding stroke caused by an aneurysm. The goal is to see if it can reduce brain damage and improve recovery.
The Hague, South HollandAges 18 years+ - NCT06360965Recruiting
Acupoint patch for pelvic pain after PID
This trial tests a skin patch treatment (acupoint application) placed on specific points of the body to help relieve ongoing pelvic pain from pelvic inflammatory disease. It may be a good option if you have moderate pain and ultrasound findings of tubal thickening or fluid.
BeijingAges 18–50 - NCT06361108RecruitingPhase 1
Spray study for diabetic nerve pain in feet
This study tests a new spray medication (YJ001) applied to the feet to see if it is safe and helps reduce pain in people with diabetic peripheral neuropathy. You may qualify if you have diabetes, stable blood sugar, and moderate to severe nerve pain in your feet.
Fredericksburg, TexasAges 18–80 - NCT06361238RecruitingPhase 3
Liraglutide to prevent confusion after heart surgery in seniors with diabetes
This trial is testing if liraglutide, a diabetes medication, can prevent delirium (sudden confusion) in older adults with type 2 diabetes who are having planned heart surgery. If you qualify, you may help find a new way to protect brain function after surgery.
Nanjing, JiangsuAges 60 years+ - NCT06362707RecruitingPhase 2
Fasudil trial for early Alzheimer's disease
This trial tests a medication called fasudil to see if it can help people with early Alzheimer's disease. It is for people who have early symptoms (mild cognitive impairment or mild dementia) and have biomarker evidence of Alzheimer's in their brain.
Tromsø, NordlandAges 50–100 - NCT06363994RecruitingPhase 3
Study of orelabrutinib plus BR for untreated mantle cell lymphoma
This trial tests a new combination of drugs (orelabrutinib plus BR) compared to BR alone for people with newly diagnosed mantle cell lymphoma who have not had treatment before. It may be an option if you are older or not able to have a stem cell transplant.
BeijingAges 60 years+ - NCT06364176RecruitingPhase 2
Adding losartan to improve Trikafta response in CF
This study tests whether adding the blood pressure medication losartan can help the standard CF drug Trikafta work better by reducing inflammation. It's for people with CF who still have high sweat chloride levels despite taking Trikafta.
Kansas City, KansasAges 12 years+ - NCT06364228RecruitingPhase 2
Oxytocin nasal spray for dementia caregivers
This study tests whether a daily oxytocin nasal spray can help reduce stress and improve well-being in women who care for a family member with dementia. You would take the spray for 10 days and have brain scans and questionnaires.
Omaha, NebraskaAges 50 years+
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Common questions
- Are there clinical trials for placebo?
- Yes. Clin2 currently lists 5,240 recruiting placebo studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a placebo trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a placebo trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.