Clinical trials
Preterm Infant clinical trials
Below are recruiting preterm infant clinical trials, each written for real people, not researchers. We’re tracking 157 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05636397Recruiting
Oral L-citrulline for fragile preterm babies with lung or bowel disease
This trial studies whether an oral medicine called L-citrulline (L-cit) is safe and how it works in very preterm infants. It includes two groups: babies with chronic lung disease (with or without high blood pressure in the lungs) and babies recovering from severe bowel infection (NEC).
Toronto, OntarioAges 1 month–6 months - NCT05617833RecruitingPhase 1
Test EPO and melatonin for brain bleeding in very preterm babies
This Phase 1 trial studies whether giving erythropoietin (EPO) and melatonin is safe in very preterm infants who have bleeding in the brain (intraventricular hemorrhage) or significant nearby brain injury. It aims to see if these medicines can be given safely during the early days after birth.
St. Petersburg, FloridaAges 12 hours–2 months - NCT05380401Recruiting
DHA and ARA milk fats for very early preterm babies
This study looks at how adding two specific milk fats (DHA and ARA) through enteral feeding affects metabolism in very early preterm infants. It may help researchers understand what these nutrients do in babies born around 25–30 weeks gestation.
Los Angeles, CaliforniaAges Up to 8 months - NCT05410340Enrolling by invitation
EEG and near-infrared testing in newborns
This study checks how newborn brains respond by using painless sensors on the head. It focuses on babies during their first month after birth, to help researchers understand early brain function and development.
Salamanca, SalamancaAges 1 week–1 month - NCT05336890Recruiting
Using past oxygen data to predict risks after premature birth
This study builds a personalized computer model that uses earlier breathing/oxygen information from preterm infants to predict possible health or development outcomes by preschool age. It may help families and doctors better estimate risks and plan support, using information already collected in a previous study.
Chicago, IllinoisAges 7 months–6.9 years - NCT05340465RecruitingPhase 2
IV iron in preterm babies to reduce blood transfusions
This Phase 2 study tests whether giving a specific IV iron (darbe plus IV iron) can help preterm babies need fewer blood transfusions while still keeping their iron levels in a safe range. It focuses on babies in the NICU who were born early, and it compares transfusion use and iron sufficiency over time.
Seattle, WashingtonAges Up to 3 days - NCT05285345Recruiting
A new discharge plan for very premature babies with lung disease
This trial tests a standardized, team-agreed discharge plan to help preterm babies with lung disease (often called BPD) leave the hospital safely. It may help by making the discharge process more consistent, especially for babies going home on breathing support like oxygen.
Boston, MassachusettsAges birth–1 year - NCT05223192Recruiting
Testing music to improve breathing and brain oxygen in preemies
This study looks at whether planned music sessions can help preterm babies breathe more steadily and improve oxygen reaching the brain. It may help staff learn how to use music therapy safely for newborns in the NICU.
New York, New YorkAges 6 months–9 months - NCT05063149RecruitingPhase 3
Bacterial lysate for preventing breathing infections in preterm infants
This study tests a medicine called a bacterial lysate, which might help prevent respiratory infections and wheezing in babies born early. It could reduce sickness and breathing problems in the first year of life.
Rotterdam, South HollandAges 1 month–2 months - NCT07596147Recruiting
Early Movement Training for At-Risk Infants
This trial tests an early intervention program called SAFE for babies aged 3–12 months who had complications at birth or were born prematurely. The goal is to help their brain and movement development through specialized therapy.
Ankara, AnkaraAges 3 months–1 year - NCT07201805Recruiting
Early Physical Therapy for High-Risk Babies
This study tests if starting physical therapy early can improve motor skills in babies who had complications at birth. It may help infants born prematurely or with conditions like bleeding in the brain, low oxygen, or infections.
Kahramanmaraş, OnikişubetAges 2 months–5 months - NCT06909929Enrolling by invitation
High-dose IV lipids for very small or early babies
This study tests whether giving a high dose of a special IV fat solution (called lipids) helps very small or very early-born babies grow better. It's for babies weighing under 1500 grams or born before 32 weeks.
Jakarta, Central JakartaAges Up to 7 months - NCT04939571Recruiting
Registry for babies with retinopathy of prematurity
This study is a European registry that collects medical information (stored electronically) about babies who have retinopathy of prematurity (ROP) severe enough to need treatment. It may help doctors understand outcomes and improve care by tracking real-world results.
SalzburgAges Any age - NCT07296003Recruiting
Motor development study in preterm and full-term babies
This study looks at how babies born early or on time develop their motor skills. Researchers will watch videos of your baby's early movements and then ask you to fill out a questionnaire about their development when they are 18 to 36 months old.
Pardubice, CzechiaAges Up to 3 years - NCT06803069Recruiting
Why newborns lose heat and how to prevent it
This study looks at why some babies, especially premature ones, have trouble keeping warm (hypothermia). It has two parts: one for babies in the neonatal ICU and one for infants under 2 having surgery. The goal is to find better ways to keep them safe and warm.
Pécs, BaranyaAges Up to 2 years - NCT06065215Recruiting
Early-life MRI to Predict Breathing Problems in Extremely Preterm Infants
This study uses an MRI scan to look at how the lungs develop in babies born very early (before 29 weeks of pregnancy). The goal is to see if early MRI images can help predict future breathing problems, so doctors can better support these infants.
Ottawa, OntarioAges 8 months–1.8 years - NCT07109856Recruiting
A new tool to predict infection in newborns
This study tests a simple non-invasive score that uses blood flow in muscles to predict if a newborn has or will develop high inflammation levels (C-reactive protein). It may help doctors start treatment earlier in babies with breathing problems.
Graz, StyriaAges birth–6 hours - NCT06687044Enrolling by invitation
Sleep therapy for better pregnancy outcomes
This study tests whether a sleep improvement therapy can help pregnant women (with one or two babies) by improving their sleep and pregnancy outcomes. It's for women who are early in their pregnancy and having sleep problems but are otherwise healthy.
Shenyang, LiaoningAges 18–45 - NCT07524517Recruiting
Face Mask Shapes for Newborn Breathing Support
This study compares two different face mask shapes used to help newborns breathe before a breathing tube is placed. Researchers want to see which mask shape works better and is easier for doctors to use.
Dublin, LeinsterAges Any age - NCT05942924Recruiting
NEU-STIM for breathing support in very premature newborns
This trial studies whether NEU-STIM can help support breathing and oxygen levels in babies born very early. If your baby is born before 32 weeks, the study may include them after you provide consent.
GrazAges Up to 7 months - NCT07176117Enrolling by invitation
Surfactant via airway device for breathing trouble in newborns
This trial tests if giving surfactant (a natural substance that helps lungs stay open) through a special airway device can help late preterm and early term infants with breathing problems. The goal is to see if this approach works better than current methods without needing a breathing tube.
Chula Vista, CaliforniaAges 8 months–9 months - NCT04821544Recruiting
Study of stress in new mothers and how it affects breastmilk
This study looks at how stress in new mothers may change their breastmilk and how that relates to newborn health outcomes. It is specifically recruiting mothers with babies in certain NICUs.
Coeur d'Alene, IdahoAges 18–50 - NCT06781476Recruiting
Urine markers in very premature babies
This study will collect urine from very premature or very low birth weight babies to look for patterns in natural chemicals (biomarkers). The goal is to find early clues about their health that could lead to better care.
Bologna, BolognaAges Any age - NCT06536296Recruiting
Music therapy for preterm brain development
This study tests if specially designed music can help premature babies' brains grow stronger and healthier. It is for very preterm infants born between 24 and 30 weeks of pregnancy.
New Haven, ConnecticutAges 6 months–7 months
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Common questions
- Are there clinical trials for preterm infant?
- Yes. Clin2 currently lists 157 recruiting preterm infant studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preterm infant trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preterm infant trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.