Clinical trials
Primary Percutaneous Coronary Intervention clinical trials
Below are recruiting primary percutaneous coronary intervention clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06959524Recruiting
Drug-coated balloon for new coronary blockages
This trial is testing a special balloon coated with medication to treat newly formed blockages in the heart's arteries. The medication may help keep the artery open after the balloon opens it during a standard procedure.
Jonesboro, ArkansasAges 18 years+ - NCT07773870Recruiting
Cold weather exposure and heart healing after stent placement
This study looks at how living or working in cold regions affects heart recovery after a stent procedure. Participants will have heart imaging at the start and again 6 months later to see if cold exposure impacts heart function.
Beijing, Please Select An Option BelowAges 18–80 - NCT06669520Recruiting
Renalase and blood vessel blockages after heart attack
This study is looking at a protein in the blood (renalase) and how it relates to blockages in tiny blood vessels after a heart attack. Researchers want to see if this protein can help predict recovery, which could lead to better treatments.
Changsha, HunanAges 18 years+ - NCT07004569Recruiting
Angiolite Registry Study for heart artery stents
This study is testing a new type of stent for people with a blockage in the main artery of the heart. It aims to see how well the stent works and if it's safe.
Hong Kong, ShatinAges 19 years+ - NCT07742345Recruiting
Coronary support catheter for safer stent placement
This study tests a catheter that helps doctors guide stents and balloons through blocked heart arteries. It may make your procedure easier and safer if you need a stent placed.
BeijingAges 18 years+ - NCT04937699RecruitingPhase 4
Switching anti-platelet tablets after a heart stent
This trial studies whether changing the timing and type of blood-thinner tablets after a heart stent is as safe and effective as continuing the same plan. It may help some people by simplifying treatment while preventing dangerous clotting after a coronary procedure.
Hangzhou, ZhejiangAges 18–80 - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT05554588Recruiting
Thrombus-finding treatments for heart attack during angioplasty
This trial compares two ways to remove or break up a blood clot during emergency heart artery opening (primary PCI) for a specific type of heart attack (STEMI). It may help patients with a high clot burden by testing whether one approach works better than the other to improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT05709626RecruitingPhase 4
Testing prasugrel alone after stent placement for heart attack
This study checks whether taking prasugrel by itself, after you get a drug-eluting stent for a heart attack (STEMI), can work as well as the standard approach. It may help prevent blood clots in the stent, but it requires specific blood-thinner plans for 12 months.
Sayama, OsakaAges 18 years+ - NCT05831085Recruiting
Compare procedures to improve heart blood flow in diabetes
This study compares two ways to restore blood flow to the heart—stent placement (PCI) versus bypass surgery (CABG)—in people with diabetes and significant multi-vessel coronary artery disease. It looks at outcomes using both standard heart tests and additional imaging/functional measurements to guide the best revascularization strategy.
Palo Alto, CaliforniaAges 20 years+ - NCT06101862Recruiting
CT scan vs. angiogram for certain heart attacks
This trial compares two ways to look at heart arteries: a CT scan (noninvasive) versus a traditional angiogram (a tube put into an artery). The goal is to see which is better for people having a certain type of heart attack.
Copenhagen, HellerupAges Any age - NCT06186037RecruitingPhase 4
Lower-dose combo vs. higher-dose alone for heart artery disease
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
Suwon, Gyeonggi-doAges 19 years+ - NCT06399692RecruitingPhase 3
Heart treatment study for women with blocked arteries
This trial is comparing two common heart procedures—bypass surgery (CABG) and stents (PCI)—to see which works better for women with blockages in multiple heart arteries. It aims to find the best treatment for women, who are often underrepresented in heart research.
Glendale, CaliforniaAges 18 years+ - NCT06399705RecruitingPhase 3
Comparing bypass surgery vs stenting for minority heart patients
This trial compares two common heart procedures—bypass surgery and stenting—for people with multiple blocked arteries. It focuses on minority groups to find out which treatment works best for them. You will be asked to fill out quality-of-life questionnaires for up to 10 years.
Glendale, CaliforniaAges 18 years+ - NCT06710210Recruiting
Hybrid scaffold-balloon vs standard stent for long blockages
This trial tests a new way to treat long, narrow blockages in heart arteries. Instead of using a standard permanent metal stent, doctors will combine a temporary scaffold with a special balloon that releases medication. The goal is to see if this approach works as well as or better than the usual metal stent.
Geneva, Canton of GenevaAges 18 years+ - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+ - NCT07436429Recruiting
Drug-coated balloon for heart attack treatment
This trial tests if a special balloon that releases medication can be used instead of a stent during emergency angioplasty for certain heart attacks. It may help patients who are having a first-time heart attack and are stable enough for the procedure.
ViennaAges 18 years+ - NCT07536802RecruitingPhase 4
Adenosine Safety and Benefit in Emergency Heart Attack Treatment
This study tests whether giving a medication called adenosine before emergency heart catheterization (a tube procedure to open blocked arteries) helps patients having a heart attack. Adenosine may protect heart tissue and improve outcomes.
Karachi, SindhAges 18–80 - NCT06795763Enrolling by invitation
New imaging & catheter system for blocked heart arteries
This trial tests a new imaging and catheter system to treat chronic total blockages in heart arteries. If you still have chest pain or other symptoms despite medical therapy, this study may help open the blockage and improve blood flow.
Atlanta, GeorgiaAges 18 years+ - NCT06460571Recruiting
Exercise after heart stent: with or without Delorme technique
This trial compares two types of cardiac rehab exercises for people age 70+ who recently got their first heart stent. It aims to see if adding progressive resisted exercises (the Delorme technique) helps improve breathing and recovery.
Sialkot, Punjab ProvinceAges 70–80 - NCT05334784Enrolling by invitation
Heart pump study for planned high-risk heart stent procedures
This study looks at using a temporary heart pump called Impella ECP during planned high-risk heart stent procedures (PCI). It may help doctors support the heart more safely while placing the stents.
Phoenix, ArizonaAges 18–90 - NCT05353140Recruiting
Left atrial appendage device vs blood thinners after stent
This trial compares a heart device that can help prevent blood clots in the heart (called LAAO) versus long-term blood thinners for people who have atrial fibrillation and recently had a stent placed. It aims to see which approach better prevents stroke and related blood-clot problems while keeping side effects manageable.
Xi'an, ShannxiAges 18 years+ - NCT07687576RecruitingPhase 2/Phase 3
Comparing clot removal methods for heart attack patients
This trial tests if a special device that sucks out blood clots during a heart attack is better than standard care for reducing clot size before placing a stent. It may help patients who have a large clot and a blocked artery.
Oxford, OxfordshireAges 18 years+ - NCT07587099Recruiting
Single vs. Dual Blood Thinners After Balloon Heart Treatment
This study compares whether patients who receive a special drug-coated balloon to open a blocked heart artery (without a stent) need to take one or two blood-thinning medications afterward. The goal is to find the safest and most effective approach for preventing future blockages.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for primary percutaneous coronary intervention?
- Yes. Clin2 currently lists 26 recruiting primary percutaneous coronary intervention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary percutaneous coronary intervention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary percutaneous coronary intervention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.