Clinical trials
Primary Prevention clinical trials
Below are recruiting primary prevention clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06499740Recruiting
Supporting teens with suicidal thoughts in primary care
This study tests a short, supportive conversation for teens with suicidal thoughts that happens in their regular doctor's office. It aims to help teens and their families get the right care without needing a hospital stay.
Centralia, WashingtonAges 10 years+ - NCT07513077Recruiting
Hearing Loss Prevention Program for Primary School Children
This study tests whether a hearing protection education program called HoorToren helps 11–12 year old children in Dutch schools prevent noise-induced hearing loss. The program teaches kids about protecting their ears from loud sounds.
RotterdamAges Any age - NCT06028113RecruitingPhase 2
A weight gain prevention program for high-risk babies in primary care
This study tests a program to help prevent unhealthy weight gain in babies at higher risk for obesity. Families will get extra support during regular check-ups at a pediatric clinic.
Cincinnati, OhioAges 1 day+ - NCT07039253Recruiting
Dating violence prevention program for teens and parents
This study tests a program during a regular check-up that helps teens and their parents learn about healthy relationships and prevent dating violence. It takes place at a primary care clinic and involves both you and your teen.
Monongahela, PennsylvaniaAges 12 years+ - NCT06397729Recruiting
Testing a new tool to support healthy habits in rural clinics
This study is testing a new way to help people improve their heart health by making healthy changes in their daily habits. It focuses on patients in rural primary care clinics who are at higher risk because of their weight.
St Louis, MissouriAges 18–64 - NCT05869552Recruiting
Screening and support to reduce suicide risk in young adults
This trial tests a support program in primary care for sexual and gender diverse young adults who screen positive for suicide risk. The goal is to help prevent suicidal thoughts and actions by offering structured support—especially through trusted people in your life.
Pittsburgh, PennsylvaniaAges 18–24 - NCT06847568RecruitingPhase 3
Adrenaline during heart artery procedure to prevent poor blood flow
This study tests whether giving adrenaline (a medicine that helps blood vessels relax) directly into the heart artery during a procedure to open a blocked artery can prevent a complication called 'no reflow' (where blood still doesn't flow well after the blockage is cleared). It is for people having a specific type of heart attack (STEMI) and being treated within 12 hours.
CairoAges 18 years+ - NCT07283939Recruiting
Testing a tool to adjust chemo doses and reduce treatment delays
This trial tests a computer algorithm called PAGODA that helps doctors adjust chemotherapy doses for people with gastrointestinal cancers. The goal is to prevent unplanned treatment delays while keeping the treatment effective.
Fairbanks, AlaskaAges 18 years+ - NCT07750249Enrolling by invitationEarly Phase 1
Short-chain fatty acids for IgA nephropathy
This trial tests whether a daily supplement of short-chain fatty acids (SCFAs) can slow down kidney damage in people with IgA nephropathy. SCFAs are substances made by gut bacteria that may help reduce inflammation and protect the kidneys.
MartinAges 18 years+ - NCT06926595RecruitingPhase 2
Stem cell transplant with low-dose chemo for graft-versus-host disease prevention
This trial tests a stem cell transplant using a reduced-intensity chemotherapy regimen and a low dose of a drug called cyclophosphamide after the transplant to help prevent graft-versus-host disease (GVHD), a common complication where donor cells attack the recipient's body. It is for people with certain blood cancers or bone marrow disorders who have a suitable donor.
Hershey, PennsylvaniaAges 18 years+ - NCT03010150Recruiting
Blood tests and swallowing exercise check-ins for head and neck cancer
This study looks at whether giving swallowing exercises and checking in with questionnaires can help people with metastatic (spreading to neck lymph nodes) head and neck cancers do the exercises correctly. It also uses blood tests to better understand adherence and progress over time.
Houston, TexasAges 18 years+ - NCT07168382Recruiting
AI-Powered Self-Care for Caregivers of Children
This study tests an AI-powered tool that helps caregivers of children find personalized resources for social needs like food, housing, or transportation. You'll use a simple app to get support for yourself and your family.
Columbus, OhioAges Any age - NCT07495124RecruitingPhase 2
IGFBP-2 vaccine to prevent ovarian cancer return
This trial tests a vaccine that targets a protein called IGFBP-2 to prevent ovarian cancer from coming back. It is for people whose CA-125 blood test shows the cancer might be returning, but who don't yet have tumors visible on scans.
Seattle, WashingtonAges 18 years+ - NCT07252700Recruiting
Prediabetes study: better care through electronic records
This trial tests if using electronic medical records can help doctors manage prediabetes better in primary care. It looks at adults with prediabetes who visit certain polyclinics and aims to prevent diabetes from developing.
SingaporeAges 21–59 - NCT04982653RecruitingPhase 2
Stitch type study to prevent hernia after liver surgery
This trial compares two ways of closing the belly incision after open liver surgery to see which best lowers the chance of getting an incisional hernia (a bulge near the scar). It may help by guiding surgeons toward the closure method that prevents hernias better.
Houston, TexasAges 18 years+ - NCT06492070RecruitingPhase 2
Cooling therapy with or without cilostazol to prevent nerve damage from paclitaxel
This study tests whether cooling your hands and feet during chemotherapy, with or without the medicine cilostazol, can help prevent nerve damage (numbness, tingling, or pain) caused by the drug paclitaxel. It is for people with gynecologic cancers who are about to start or have just finished paclitaxel treatment.
Atlanta, GeorgiaAges 18 years+ - NCT07496996Recruiting
Support program for disability transitional care stays
This study looks at whether a special support program can help prevent problems and improve the experience of people with disabilities during a 4-week stay in a transitional care unit. The study also includes family or friend caregivers to see how the program works for them as well.
RennesAges 18 years+ - NCT06550141RecruitingPhase 2
Preventing side effects of CAR-T therapy for large B-cell lymphoma
This trial tests whether a drug called emapalumab can reduce serious side effects from CAR-T cell therapy, a treatment for large B-cell lymphoma that has come back or not responded to earlier treatments. If you qualify, you would receive emapalumab alongside your CAR-T treatment to help make it safer.
Boston, MassachusettsAges 18 years+ - NCT06839456RecruitingPhase 1/Phase 2
Stem cell addback to prevent infections after transplant
This trial tests whether adding back certain immune cells after a stem cell transplant can help prevent serious viral or fungal infections. It's for children and young adults up to age 25 who need a transplant for a blood cancer or other curable disease.
Philadelphia, PennsylvaniaAges 1 month–25 years
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Common questions
- Are there clinical trials for primary prevention?
- Yes. Clin2 currently lists 91 recruiting primary prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.