Clinical trials
Primary Prevention clinical trials
Below are recruiting primary prevention clinical trials, each written for real people, not researchers. We’re tracking 89 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07541716Recruiting
Parenting support to help infants with feeding and sleep difficulties
This study tests a new parenting program designed to help parents of young infants who have feeding, sleeping, or crying challenges. The program uses video lessons and a mobile app to teach parents techniques that may help their baby become calmer and more regulated.
AntwerpAges 18 years+ - NCT05976867Recruiting
Parent program to prevent child sexual abuse
This study tests whether a parent-focused program can prevent child sexual abuse by teaching parents skills to support their children. You may be able to help both the program work better and learn how well it can be used in real life.
New York, New YorkAges 15 years+ - NCT06865885RecruitingPhase 4
Lowering cholesterol with inclisiran in people on many medications
This study tests a new injectable medicine called inclisiran for people who are already on many medications and have high cholesterol. It is designed for those who cannot lower their cholesterol enough with statins, especially if they have diabetes or other heart risks.
La Jolla, CaliforniaAges 18–85 - NCT04974138RecruitingPhase 4
Preventing first stroke in people with high-risk blood pressure
This trial tests whether a study medicine regimen can help prevent a first stroke in people with hard-to-control “high homocysteine” risk factors linked to a specific gene type. You may qualify if you have certain blood pressure levels, a specific MTHFR gene result, and related blood test findings.
Bengbu, AnhuiAges 45–74 - NCT04974151RecruitingPhase 4
Prevention trial for stroke risk in people with high blood pressure
This trial tests an approach to prevent first-time stroke and heart problems in people with high blood pressure who also have a specific genetic test result (MTHFR 677 TT). It may help by lowering risk before a first stroke happens.
Bengbu, AnhuiAges 45–74 - NCT05089227RecruitingPhase 2
Long-term apixaban to prevent clots in autoimmune hemolytic anemia
This Phase 2 trial tests whether taking long-term apixaban (a blood thinner) can prevent venous blood clots in people with autoimmune hemolytic anemia (AIHA). It may help reduce the risk of dangerous clotting events if you meet safety and risk criteria.
DijonAges 18 years+ - NCT05309850Recruiting
Lifestyle tool for preventing diabetes risk
This study tests a lifestyle “tool” to help people reduce their risk of developing diabetes. It is for adults over 35 who do not have certain types of diabetes already.
MalmöAges 35 years+ - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT05720507Recruiting
Testing a coffee-movement program to prevent frailty
This trial studies a program called “Cafe Move” to help people stay physically strong and avoid future frailty. It’s aimed at people who currently live independently and can move on their own.
Missoula, MontanaAges 50–85 - NCT05781295Recruiting
Taurolidine vs saline lock for kids’ central line
This trial studies whether a medicine lock called taurolidine is safer or works better than a standard saline (salt water) lock for pediatric cancer patients with central venous lines. It’s meant to help prevent central-line infections.
ParisAges Up to 21 years - NCT06186037RecruitingPhase 4
Lower-dose combo vs. higher-dose alone for heart artery disease
This trial compares a lower-dose cholesterol pill (rosuvastatin plus ezetimibe) to a higher-dose version of just rosuvastatin for people with mild to moderate heart artery blockages who have not had a stent or bypass. It aims to see which approach works better and is safer.
Suwon, Gyeonggi-doAges 19 years+ - NCT06543173Recruiting
Preventive heart ablation with defibrillator in high-risk patients
This study tests if doing a special heart procedure (catheter ablation) at the same time as implanting a defibrillator (ICD) can prevent dangerous heart rhythms better than the ICD alone. It is for people with a very weak heart pump due to blocked arteries who are getting a first-time ICD.
Copenhagen, Region HAges 18 years+ - NCT06594783RecruitingPhase 4
Preventing varices bleeding with carvedilol and banding
This trial tests whether adding endoscopic banding helps prevent bleeding from enlarged varices in people with cirrhosis who still have high-risk varices despite taking carvedilol.
TaipeiAges 18–90 - NCT06615791Recruiting
FIT FIRST Teen School Program Study
This study looks at a new school program to improve fitness and health in teens. It tests if the activities help you stay active and feel better.
OdenseAges 13–16 - NCT06722521RecruitingPhase 4
Comparing two treatments for high coronary calcium without symptoms
This trial compares a combo of statin and ezetimibe without aspirin against statin alone with aspirin in people with high coronary calcium but no blocked arteries. It aims to find which approach is safer and more effective without causing bleeding risk.
SeoulAges 19 years+ - NCT06793930Recruiting
A personalized program to improve health in metabolic syndrome
This study tests a personalized program that helps people with metabolic syndrome make healthy changes to their diet and activity. It is designed for Chinese adults who live at home and can use a digital device.
Hong KongAges 18 years+ - NCT07045623Recruiting
Better care and education for high cholesterol
This study compares two ways of managing high cholesterol: a more intensive program with extra support versus the usual care and education. It's for people with high blood pressure or diabetes who are already part of a community health program.
Gyeonggi-do, Suwon-siAges 30–80 - NCT07245069RecruitingPhase 2
Can dapagliflozin protect the heart during breast cancer chemo?
This trial tests if the drug dapagliflozin can prevent heart damage caused by anthracycline chemotherapy in breast cancer patients. It aims to see if taking the drug during chemo helps keep your heart healthy.
LjubljanaAges 18 years+ - NCT06676280RecruitingPhase 4
Aspirin and statin study for high coronary calcium
This trial tests whether a daily aspirin and a statin medicine can help prevent heart problems in people with high calcium buildup in their heart arteries. It is for people aged 40 to 75 who have a high coronary calcium score (300 or more) and at least one additional risk factor like diabetes or high blood pressure.
AnyangAges 40–75 - NCT07414719Recruiting
HPV vaccine study for teens and teachers in AuRA
This study tests a program to increase HPV vaccination among teens aged 11-17 in public schools. It aims to see if education and support can help more adolescents get the vaccine to prevent HPV-related cancers.
Saint-PriestAges 11–17 - NCT07611747RecruitingPhase 4
Ultrasound Screening to Prevent Heart Disease in Rheumatic Patients
This study tests whether using ultrasound to look at arteries in the neck can help prevent heart attacks and strokes in people with inflammatory joint diseases like rheumatoid arthritis or lupus. Researchers will use the results to guide treatment decisions.
Alicante, AlicanteAges 50 years+ - NCT05267990Enrolling by invitation
CT calcium scan to prevent heart problems in diabetes
This trial studies whether using a heart CT “calcium score” to guide prevention can lower the chance of major heart disease in people with type 2 diabetes who have other heart risk factors. It may help by targeting prevention more personally, based on your calcium score.
YilanAges 40 years+ - NCT06646601Recruiting
Garden-based program for heart and stroke recovery
This trial tests a preventive program that uses a therapeutic garden to help people with heart or blood vessel conditions. It looks at whether patients find the program helpful and easy to take part in.
GapAges 18 years+ - NCT06077253Recruiting
Preventing angle closure glaucoma in Danish patients
This trial tests a laser treatment to prevent a type of glaucoma called angle closure. It is for people who have a narrow drainage angle in the eye but do not yet have glaucoma or other serious eye conditions.
AalborgAges 40–80
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Common questions
- Are there clinical trials for primary prevention?
- Yes. Clin2 currently lists 89 recruiting primary prevention studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a primary prevention trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a primary prevention trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.