Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 718 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06636123RecruitingPhase 1
Testing GZ17-6.02 for advanced prostate cancer after hormone therapy
This trial tests a new drug combination (GZ17-6.02) for men with advanced prostate cancer that has stopped responding to standard hormone therapies. The goal is to see if the drug can help slow down the cancer.
Richmond, VirginiaAges 18 years+ - NCT06896708Recruiting
Intensive cholesterol treatment for heart plaque in younger adults
This trial tests whether higher doses of cholesterol-lowering medication (statins) can slow down plaque buildup in the heart arteries of younger and middle-aged adults with stable chest pain. It may help prevent heart attacks and the need for procedures like stents.
Chongqing, Chongqing MunicipalityAges 18–60 - NCT05823636Recruiting
Tracking why new indigestion turns into functional indigestion
This study follows adults with new indigestion symptoms to understand what factors make symptoms persist and possibly develop into functional dyspepsia. It may help future care by identifying who is more likely to get worse and why.
Xi'an, ShaanxiAges 18 years+ - NCT07369596Recruiting
Chemotherapy doses and survival in older lung cancer patients
This study looks at how lowering chemotherapy doses affects survival in older patients with advanced lung cancer who do not have certain genetic mutations. It may help doctors understand the best way to treat this group.
Hong KongAges 65 years+ - NCT07315178Recruiting
Digital twin study for chronic aortic dissection
This study is creating a digital twin model to predict how chronic thoracic aortic dissection progresses. If you have a type A or type B aortic dissection, this study may help researchers better understand your condition without additional stress or invasive procedures.
DijonAges 18 years+ - NCT03930810Enrolling by invitation
Study of PFIC types and how bile diversion affects outlook
This study looks at different genetic liver conditions called PFIC and follows how they progress over time. It also studies whether a procedure called biliary diversion may improve symptoms or long-term outcomes.
Groningen, Provincie GroningenAges birth–65 years - NCT06940037Recruiting
Aging biology and strength training in older adults
This study looks at how aging affects the way older adults respond to resistance training (exercises using weights or resistance bands). It compares two types of training to see which works better for improving mobility and strength.
Boston, MassachusettsAges 65 years+ - NCT06924606RecruitingPhase 2
Testing JS207 for advanced lung cancer after prior treatments
This trial tests a new drug called JS207 for people with advanced non-small cell lung cancer (NSCLC) that has gotten worse after standard treatments like chemotherapy and immunotherapy. It aims to see if JS207 can help shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18–75 - NCT06752057Recruiting
Personalized vaccine plus immunotherapy and radiation for advanced lung cancer
This study tests a combination of a personalized vaccine made from your tumor's unique markers, a type of immunotherapy (PD-1 inhibitor), and radiation. The goal is to see if this mix can work better for advanced lung cancer that has progressed after initial treatment.
Nanchang, JiangxiAges 18–70 - NCT06866041Recruiting
Prostate cancer markers and imaging for low-risk patients on active surveillance
This trial looks for new markers and advanced scans to better predict which low-risk prostate cancers might grow. If you have low-risk prostate cancer and are managing it with active surveillance, researchers want to see if PSMA-PET scans and tissue markers can give earlier warning of progression.
Milan, ItalyAges 45–80 - NCT06826092RecruitingPhase 2
Metformin for advanced colorectal cancer with chemotherapy
This trial tests whether adding metformin (a diabetes drug) to standard chemotherapy (FOLFIRI) and targeted therapy can help people with metastatic colorectal cancer live longer or respond better to treatment.
Kaohsiung CityAges 20–90 - NCT07601906Recruiting
Blood Flow Exercise Therapy After Knee Replacement Surgery
This study tests whether special exercises that temporarily reduce blood flow to your leg can help you recover better after knee replacement surgery. It focuses on reducing pain and improving your ability to bend and straighten your knee.
Lahore, Punjab ProvinceAges 50–65 - NCT04521972Recruiting
Testing how room light affects labor and uterine contractions
This study looks at whether changing the light you’re exposed to (using blue-filter glasses and adjusting lighting) changes uterine contractions and how labor progresses. You’d also track your lighting and use a home monitor that measures contraction activity.
East Lansing, MichiganAges 18–42 - NCT05678166Recruiting
Testing a blood marker to predict worsening lung mycobacterial disease
This study checks whether a blood test called soluble programmed death-1 can help predict how nodular-bronchiectatic nontuberculous mycobacterial (NTM) lung disease will progress. Results may help doctors monitor patients more accurately and decide when to treat or follow more closely.
TaipeiAges 20 years+ - NCT07014111Recruiting
Fight Fatigue: muscle relaxation and walking for dialysis patients
This study tests a simple program that combines muscle relaxation exercises and walking to help reduce fatigue in people with end-stage kidney disease who are on dialysis. You'll receive text messages to guide you and track your progress.
Chicago, IllinoisAges 18 years+ - NCT07236671Recruiting
Study of enlarged eye blood vessel changes
This study looks at how certain enlarged blood vessels in the back of the eye change over time. By taking special images, researchers hope to learn more about these vessels. It might help if you have been told you have pachyvessels.
Hong KongAges 45 years+ - NCT05654922RecruitingPhase 3
Prevent lung transplant airways scarring with ARINA-1
This Phase 3 trial tests ARINA-1 to slow or prevent worsening lung transplant scarring in the breathing tubes (bronchiolitis obliterans). It may help people who are showing early decline in lung function but are not yet at advanced disease.
Phoenix, ArizonaAges 18–75 - NCT07265596RecruitingPhase 2
Brain Scan Study for Early Parkinson's Disease
This trial uses a special brain scan (PET scan) to look at early changes in people who have early signs of Parkinson's disease. The goal is to learn more about how Parkinson's develops over time.
New Haven, ConnecticutAges 18 years+ - NCT07249112Recruiting
Genomic study of metabolic fatty liver disease
This study aims to understand the genetic factors behind metabolic fatty liver disease (MASLD) by comparing patients with advanced liver scarring or liver cancer to healthy blood donors. It may help doctors better predict and treat the disease in the future.
Milan, MilanoAges 18–90 - NCT07317193Recruiting
Genetic causes of adult bile duct disease
This study looks for new genes that might cause abnormal liver test results or specific bile duct diseases in adults, when standard testing hasn't found a clear cause. It also uses healthy blood donors as a comparison group.
Milan, MilanoAges 18–65 - NCT06843356Recruiting
Endovascular treatment for worsening mild stroke with basilar artery blockage
This trial tests a procedure to open a blocked artery in the back of the brain (basilar artery) for people who had a mild stroke that later got worse. If you are eligible, you may receive this treatment up to 24 hours after your symptoms worsen.
Wuhu, AnhuiAges 18 years+ - NCT06820931RecruitingPhase 4
Chinese medicine for girls with early puberty
This trial tests whether a Chinese herbal formula (nourishing yin, reducing fire) can help slow down rapid puberty in girls who started showing signs between 8 and 9 years old, before standard treatments are typically used. It aims to see if this option is safe and effective.
Shanghai, Shanghai MunicipalityAges 8–9 - NCT06799663Recruiting
Smartphone use and its effects on kids' posture and fitness
This study looks at how smartphone addiction affects posture, fitness, and intelligence in children and teens aged 9 to 18. It aims to understand the physical and mental impacts of heavy phone use.
KafrelsheikhAges 9–18 - NCT05641831RecruitingPhase 2
Canakinumab to prevent clonal blood count problems turning into cancer
This Phase 2 study tests canakinumab to help stop high-risk clonal cytopenias of unknown significance (CCUS) from progressing into a blood cancer. If you have persistent low blood counts and specific genetic features, this treatment may lower the chance of progression.
Miami, FloridaAges 18 years+
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 718 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.