Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 716 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06845410Recruiting
INR-CAD: inflammation-related coronary artery disease study
This study follows people who have both coronary artery disease (narrowed heart arteries) and signs of chronic inflammation to learn more about their condition, current treatments, and outcomes. It helps doctors understand how best to care for patients like you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06843005Recruiting
Heart CT scan study for plaque changes in mild coronary disease
This study uses repeat CT scans of the heart to see how plaque buildup changes over time in people with mild, non-blocking coronary artery disease. It may help doctors decide on better treatments to prevent future heart problems.
Nanjing, JiangsuAges 18–80 - NCT06838676RecruitingPhase 2
ACT001 for Newly or Previously Treated Brain Stem Glioma
This trial tests the drug ACT001 in people with a type of brain tumor called DIPG or other related high-grade gliomas. It aims to see if the drug can help control the tumor and improve outcomes.
Aurora, ColoradoAges 1–39 - NCT06844643Recruiting
Axial spondyloarthritis progression study in China
This study tracks how axial spondyloarthritis progresses over time in Chinese patients. It helps doctors understand the natural course of the disease and improve care.
BeijingAges 18 years+ - NCT06839469Recruiting
Walking study for rare muscle and nerve conditions
This study looks at how children and teens with Duchenne muscular dystrophy (DMD) or spinal muscular atrophy (SMA) walk, by having them do walking tests while wearing sensors. The goal is to find better ways to track how these diseases progress and how treatments work over time, without needing blood tests or scans.
Palo Alto, CaliforniaAges 5 years+ - NCT06033287Recruiting
Real-world study of CDK4/6 inhibitors plus hormone therapy for advanced breast cancer
This study looks at how well CDK4/6 inhibitors combined with hormone therapy work in real-world settings for people with a certain type of advanced breast cancer (HR+/HER2-). It aims to understand the best treatment path and what happens next.
Changsha, HunanAges 18 years+ - NCT06816446Recruiting
Do special glasses slow myopia in children?
This trial tests whether special Rodenstock glasses can slow down the worsening of nearsightedness (myopia) in children. It's for kids aged 6 to 12 who have never had myopia treatment before.
SingaporeAges 6–12 - NCT06824064RecruitingPhase 2
RBS2418 for advanced metastatic colorectal cancer
This trial tests a new drug called RBS2418 for people with advanced colorectal cancer that has spread and is getting worse, even after other treatments have stopped working. The goal is to see if RBS2418 can help control the cancer.
Newark, DelawareAges 18 years+ - NCT06815029RecruitingPhase 1
Modified immune cells for recurrent brain cancer
This trial tests a new treatment using your own immune cells that are genetically modified to find and attack brain tumor cells. It is for people with a type of brain cancer that has come back after standard therapy.
Duarte, CaliforniaAges 18 years+ - NCT06808100Enrolling by invitation
Can a blood test predict organ failure in septic shock?
This trial is studying a blood marker called GDF-15 to see if it can predict which patients with septic shock might develop multiple organ failure. If you have septic shock and do not have certain other serious health conditions, you may be able to join.
AnkaraAges 18 years+ - NCT06793709Recruiting
Study of Tasfygo for bile duct cancer with FGFR2 gene change
This study is watching people with a certain type of bile duct cancer that has a specific gene change (FGFR2 fusion). It looks at what happens when they take the drug Tasfygo after their cancer did not respond to chemotherapy.
TokyoAges Any age - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06059469RecruitingPhase 2
PSMA scan for advanced triple-negative breast cancer
This trial uses a special scan (PSMA-PET/CT) to see if your breast cancer makes a protein called PSMA. The results might help guide your future treatment.
BrusselsAges 18 years+ - NCT06780670RecruitingPhase 2/Phase 3
Comparing a new treatment to standard care for advanced prostate cancer
This study tests a new drug (AAA817) against the usual treatments for men with advanced prostate cancer that has stopped responding to a type of targeted radiation therapy (Lu-PSMA). The goal is to see if the new drug can slow the cancer's growth better than standard options.
Scottsdale, ArizonaAges 18–100 - NCT05181033RecruitingPhase 2
Lenvatinib plus letrozole versus fulvestrant for metastatic breast cancer
This Phase 2 study compares a combination medicine (lenvatinib plus letrozole) against fulvestrant to treat metastatic estrogen-receptor positive, HER2-negative breast cancer after the cancer has grown despite hormone therapy plus a CDK4/6 inhibitor. It may help by finding a more effective treatment option after your first lines have stopped working.
SingaporeAges 18–99 - NCT06768762Recruiting
Home activity program for knee replacement recovery
This study tests a home-based physical activity program for adults who have had a knee replacement at least a year ago. It aims to help you become more active with remote support and coaching.
Columbia, South CarolinaAges 18 years+ - NCT05663840Recruiting
Exercise program study for focal neck dystonia
This trial tests how a structured exercise program affects the brain and body changes behind focal cervical dystonia (a movement disorder that causes abnormal neck postures). It may help people who are still having symptoms despite best-available treatments like botulinum toxin injections or medicines.
Gainesville, FloridaAges 30–85 - NCT06254469RecruitingPhase 3
PET scan study for memory decline with head injury or Alzheimer's risk
This trial uses a special PET scan tracer to see if it can predict who will get worse over time. It is for people with mild memory or thinking problems that may be linked to past head injuries or early Alzheimer's disease.
Evanston, IllinoisAges 45 years+ - NCT06747845RecruitingPhase 2
Maintenance therapy for stable metastatic pancreatic cancer
This trial tests a combination of two drugs, niraparib and ipilimumab, as a maintenance treatment for people with metastatic pancreatic cancer that has not grown after initial chemotherapy. The goal is to see if this can help keep the cancer stable longer.
Boston, MassachusettsAges 18 years+ - NCT06739967Recruiting
Speech Therapy for Italian Speakers with PPA
This study tests speech and language therapy for people with primary progressive aphasia (PPA). It aims to see if targeted exercises can help maintain or improve communication skills.
BariAges 40–85 - NCT06733363RecruitingPhase 2
Vegetable diet to prevent bladder cancer return
This trial tests whether a diet rich in cruciferous vegetables (like broccoli, cauliflower, and kale) can help prevent bladder cancer from coming back or getting worse. It is for people with early-stage, non-invasive bladder cancer who live in New York State.
Buffalo, New YorkAges 18 years+ - NCT06727253Recruiting
Glycan supplement study for Crohn's disease after surgery
This trial tests whether a glycan supplement can prevent Crohn's disease from coming back after surgery to remove the diseased part of the small and large intestine. It may help people who have had this specific surgery and are not taking certain other treatments.
Lisbon, Lisbon DistrictAges 18–75 - NCT06733636Recruiting
Smell training for older adults with smell loss
This study tests whether a special device can help older adults regain their sense of smell through regular training with different scents. It is designed for people who have lost smell due to aging or other causes, not from birth.
Baltimore, MarylandAges 60 years+ - NCT06736795Recruiting
Online support for Achilles tendon loading exercises
This study tests whether extra support from a clinician during a progressive exercise program helps people with Achilles tendon pain improve faster. You'll do exercises that gradually increase the load on your tendon, with guidance from a physical therapist via video visits.
Iowa City, IowaAges 18–60
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 716 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.