Clinical trials
Progression clinical trials
Below are recruiting progression clinical trials, each written for real people, not researchers. We’re tracking 716 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07005323Recruiting
Treatment for age-related macular degeneration that has not improved with standard therapy
This trial tests a new treatment for people with a specific type of age-related macular degeneration (AMD) that has not improved after standard anti-VEGF injections. The goal is to see if it can stop vision loss and reduce retinal damage.
Nagoya, Aichi-kenAges 18–85 - NCT07010263RecruitingPhase 3
AK112 for limited-stage small cell lung cancer after chemoradiation
This study tests a new drug called AK112 (a bispecific antibody that blocks both PD-1 and VEGF) as a consolidation treatment to help prevent your limited-stage small cell lung cancer from coming back after you've finished chemoradiation. It's for people whose cancer has not grown following concurrent chemotherapy and radiation.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07003542RecruitingPhase 2
Sitagliptin for people with high-grade brain tumors
This trial tests whether sitagliptin, a medicine usually used for diabetes, can help people with a fast-growing type of brain tumor (grade 4 glioma). You will take sitagliptin before your planned surgery, and researchers will study how it affects your tumor.
Cleveland, OhioAges 18 years+ - NCT07008716RecruitingPhase 3
Omitting CTV for primary tumor in limited-stage small cell lung cancer
This trial tests whether treating the main tumor alone, without the nearby lymph nodes, can work as well in limited-stage small cell lung cancer after initial chemotherapy. You may qualify if you have not had disease progression after 2-4 cycles of standard chemo and meet other health criteria.
Guangzhou, GuangdongAges 18–75 - NCT07001800RecruitingPhase 2/Phase 3
Slowing aortic valve disease with ataciguat
This trial tests a new pill, ataciguat, to slow down the progression of moderate calcific aortic valve stenosis (a condition where your aortic valve stiffens). If you have moderate valve narrowing and meet the other criteria, participation could help find a way to delay needing surgery.
Birmingham, AlabamaAges 50 years+ - NCT05775484Recruiting
Exercise program to slow heart and blood vessel aging
This trial tests whether a structured exercise program can slow how quickly your cardiovascular system (heart and blood vessels) “ages” over time. If you’re able to move around outdoors safely, exercise may be a key part of the study.
Singapore, SingaporeAges 21–100 - NCT06975332Recruiting
Targeted radiation therapy for recurrent high-grade glioma
This trial tests a new radiation treatment that targets tumor cells directly. It may help people with a specific type of aggressive brain tumor that has grown after standard treatments.
Warsaw, PolandAges 18–80 - NCT06943872RecruitingPhase 3
Comparing new treatments for relapsed CLL or SLL
This study tests a combination of sonrotoclax plus obinutuzumab or rituximab versus the current standard venetoclax plus rituximab for people whose CLL or SLL has come back or not responded to previous treatment. The goal is to see which approach helps keep the cancer from growing longer.
Laguna Hills, CaliforniaAges 18 years+ - NCT06951217RecruitingPhase 2
Long-term safety study of an inhaled drug for lung scarring
This study continues treatment for people who already completed a previous study with an Avalyn inhaled antifibrotic drug. It aims to check the long-term safety of the medication for patients with certain types of lung scarring.
Birmingham, AlabamaAges 18 years+ - NCT06305663Recruiting
Contact lens to slow myopia in children
This study tests a special contact lens designed to slow the progression of nearsightedness (myopia) in children ages 8 to 12. If your child is nearsighted and needs glasses, this lens might help reduce the need for stronger prescriptions over time.
Beijing, Beijing MunicipalityAges 8–12 - NCT06940037Recruiting
Aging biology and strength training in older adults
This study looks at how aging affects the way older adults respond to resistance training (exercises using weights or resistance bands). It compares two types of training to see which works better for improving mobility and strength.
Boston, MassachusettsAges 65 years+ - NCT06922994RecruitingPhase 2
Testing atorvastatin for arrhythmogenic cardiomyopathy
This trial tests if a common cholesterol medicine, atorvastatin, can slow the progression of arrhythmogenic cardiomyopathy, a genetic heart condition that can cause abnormal heart rhythms. If you have this condition, joining this study may help researchers find a new way to protect your heart.
Pavia, PVAges 18 years+ - NCT06893471Enrolling by invitation
Goal setting for healthier municipal workplaces
This study tests a new way of setting and tracking work environment goals, called Goal Attainment Scaling (GAS). It aims to replace yearly check-ins with regular progress updates to improve daily work life.
Hudiksvall, Gävleborg CountyAges Any age - NCT06896162Recruiting
Genetic test to guide first or second treatment for advanced cancer
This study looks at whether using a detailed genetic test of your tumor can help pick the best first or second treatment for advanced lung, colon, breast, or bladder cancer. The goal is to see if this personalized approach helps people live longer.
Chapel Hill, North CarolinaAges 18 years+ - NCT06896708Recruiting
Intensive cholesterol treatment for heart plaque in younger adults
This trial tests whether higher doses of cholesterol-lowering medication (statins) can slow down plaque buildup in the heart arteries of younger and middle-aged adults with stable chest pain. It may help prevent heart attacks and the need for procedures like stents.
Chongqing, Chongqing MunicipalityAges 18–60 - NCT06894927Enrolling by invitation
Hearing check for adults 50 and over
This trial offers a free hearing check for adults aged 50 and older. It aims to detect any hearing changes early and can help you understand your hearing health better.
Hradec Králové, Czech RepublicAges 50 years+ - NCT06878664RecruitingPhase 3
Lu177-Dotatate vs standard care for slow-growing midgut neuroendocrine tumors
This trial tests whether a radioactive drug called Lu177-Dotatate (PRRT) works better than usual care for people with slow-growing, advanced midgut neuroendocrine tumors (NETs). It may help shrink or slow the growth of tumors when you also get somatostatin analog therapy.
Caen, CaenAges 18 years+ - NCT06863311RecruitingPhase 2
Trial of zanzalintinib with immunotherapy for advanced kidney cancer
This trial tests a new drug combination for people with advanced clear cell kidney cancer that has gotten worse after initial immunotherapy treatment. The goal is to see if adding zanzalintinib to another immunotherapy can help control the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT05789433Recruiting
Aerobic exercise study after colon or rectal cancer surgery
This trial studies whether a supervised aerobic exercise program helps muscles “remodel” (change/strengthen) after colon or rectal cancer treatment. It may help people improve physical function during recovery, but you can only join if it’s safe for you and you can follow the study plan.
Orlando, FloridaAges 18 years+ - NCT06800651RecruitingPhase 2
A new drug for fast-growing polycystic kidney disease
This trial tests a drug (JMKX003142) for people with autosomal dominant polycystic kidney disease that is getting worse quickly. It may help slow down kidney damage.
Beijing, Beijing MunicipalityAges 18–55 - NCT06850168Recruiting
Can special glasses slow down nearsightedness in children?
This trial tests a new type of spectacle lens designed to slow the progression of nearsightedness (myopia) in children. If your child is between 6 and 10 years old, has mild to moderate nearsightedness, and is willing to wear glasses full-time for two years, this study may be a good fit.
SingaporeAges 6–11 - NCT06856213RecruitingPhase 2
Cetuximab with or without weekly paclitaxel for head and neck cancer
This study tests whether adding the chemotherapy drug paclitaxel (Taxol) to the targeted therapy cetuximab (Erbitux) is more effective than cetuximab alone for head and neck cancer that has progressed after initial immunotherapy and chemotherapy. Researchers want to see if the combination can help shrink tumors or slow the disease.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06232083RecruitingPhase 1
Study of Caronizumab with low-dose radiation for certain cancers
This trial tests a combination of an immunotherapy drug (Caronizumab) and a special type of low-dose radiation (PLDR) for people with esophageal, lung, or cervical cancer that has come back or spread after initial treatment. It aims to see if the combination can help stop the cancer from growing.
Hefei, British ColumbiaAges 18–75 - NCT06839144RecruitingPhase 2
Medications before surgery to slow ovarian cancer growth
This trial tests whether giving two common medications before and after surgery can slow the growth of ovarian cancer. The medications may help reduce stress signals that could make cancer spread faster during surgery.
Ramat GanAges 20–85
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Common questions
- Are there clinical trials for progression?
- Yes. Clin2 currently lists 716 recruiting progression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a progression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a progression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.