Clinical trials
Propofol clinical trials
Below are recruiting propofol clinical trials, each written for real people, not researchers. We’re tracking 108 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07561970Recruiting
Comparing two anesthesia drugs during heart rhythm procedures
This study compares two commonly used anesthesia medications (propofol and sevoflurane) in patients having a procedure to treat irregular heartbeats. Researchers want to see which drug works better and is safer for keeping you asleep during the procedure.
BrusselsAges 18 years+ - NCT07534956Recruiting
Anesthesia Methods and Waking Up Agitation in Children
This study compares different anesthesia approaches to see which one helps children wake up more calmly after urogenital surgery (surgery on the urinary or reproductive system). Researchers want to find the best way to reduce agitation and confusion as children wake up from anesthesia.
IstanbulAges 3–10 - NCT07456111RecruitingPhase 4
Comparing two sedatives for colonoscopy with polyp removal
This trial compares two sedative medications, remimazolam and propofol, to see which works better and is safer for people having a colonoscopy to remove polyps. It could help choose a sedation option with fewer side effects.
ZagrebAges 18–60 - NCT06138340Recruiting
How anesthesia affects brain networks in people with glioma
This study looks at how different anesthetics change brain connections during surgery for a type of brain tumor called glioma. It may help doctors choose the best anesthesia for your surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07395596RecruitingPhase 4
Remimazolam for Bronchoscopy in High-Risk Patients
This trial tests a sedative called remimazolam for people who are at higher risk during a painless bronchoscopy (a lung exam). It aims to see if this drug is safe and effective for you.
Hangzhou, ZhejiangAges 18 years+ - NCT06716840Recruiting
Remimazolam for sedation after heart surgery
This trial tests a medication called Remimazolam Besylate to sedate patients who need a breathing tube after heart surgery. The goal is to help patients relax while they recover in the intensive care unit.
Hangzhou, ZhejiangAges 18 years+ - NCT07294092RecruitingEarly Phase 1
Brain imaging study of ketamine and propofol
This study uses MRI scans to see how two common sedatives, ketamine and propofol, affect brain activity. It may help explain how these drugs work differently in the brain.
Pittsburgh, PennsylvaniaAges 18–59 - NCT07213544RecruitingPhase 4
Comparing two sedatives for laser burn treatments
This trial tests if remimazolam or propofol works better for people getting two laser treatments for burn scars on different days. It aims to find which drug helps you relax more comfortably during the procedure.
Charleston, South CarolinaAges 18 years+ - NCT07198711Enrolling by invitationPhase 1
Dream induction during sleep with anesthesia and brain monitoring
This study tests whether we can safely and reliably induce dreaming in healthy adults using anesthesia and brain wave (EEG) monitoring. You would be given a low dose of an anesthetic and then monitored as you fall asleep to see if dreams can be triggered.
Stanford, CaliforniaAges 18–70 - NCT05990790RecruitingPhase 4
Comparing anesthetics and their effect on confusion after surgery
This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.
InnsbruckAges 65 years+ - NCT07144007Recruiting
Preventing agitation after rhinoplasty with propofol and dexmedetomidine
This study tests whether giving two medicines, propofol and dexmedetomidine, during rhinoplasty can help prevent confusion or restlessness when waking up from anesthesia. It may be a good option if you are having nose surgery and are generally healthy.
Van, TuşbaAges 18–65 - NCT06777758RecruitingPhase 4
Comparing two sedatives for endoscopy procedures
This trial compares two sedative medications, Remimazolam and Propofol, to see which works better for upper GI endoscopy exams and treatments. The goal is to help doctors choose the best option for patients.
Kaohsiung CityAges 20–80 - NCT07116733RecruitingPhase 3
Comparing two anesthetics for heart bypass surgery
This trial compares two types of anesthesia (desflurane gas vs. propofol IV) during coronary artery bypass surgery to see which one is better for your heart. It might help patients who are having planned bypass surgery.
Fuzhou, FujianAges 18 years+ - NCT06927076Recruiting
DMT with propofol for depression
This study tests whether a combination of DMT (a psychedelic) and propofol (a sedative) can help treat depression. You will receive both medicines in a hospital setting, and the team will monitor your response.
BaselAges 21 years+ - NCT06867549RecruitingPhase 2
Propofol for depression in older adults
This study tests if a medicine called propofol (given through an IV) can help improve depression symptoms by boosting slow brain waves during sleep. It is for people 60 and older whose depression has not fully responded to standard antidepressants.
St Louis, MissouriAges 60 years+ - NCT06750939Recruiting
Comparing two sedatives for ICU breathing tube placement
This study compares two medicines (propofol and ketamine) used to help you relax and stay stable while a breathing tube is placed. The goal is to see which one is safer for your heart and blood pressure during this procedure in the ICU.
Köseköy, KocaeliAges 18 years+ - NCT05728775RecruitingPhase 4
Comparing two anesthetics after major non-heart surgery
This trial compares the anesthesia medicines remimazolam and propofol during major surgery to see how patients do afterward. It may help guide which anesthetic is safer or leads to better recovery in higher-risk patients.
Hefei, AnhuiAges 45 years+ - NCT06449430Recruiting
Turning a Breech Baby: Sleep vs. Spinal Numbing
This trial compares two ways to help turn a breech baby to a head-down position: one uses a light sleep medicine (propofol), the other uses numbing medicine in the spine (bupivacaine). The goal is to make the turning attempt more comfortable and successful.
Murcia, MurciaAges 18 years+ - NCT05991453Recruiting
Recovery after IV vs. inhaled anesthesia for non-cardiac surgery
This trial compares recovery after two types of general anesthesia: one given through an IV (propofol) and one inhaled as a gas. It aims to see which approach leads to a smoother recovery for people having non-cardiac surgery.
Little Rock, ArkansasAges 18 years+ - NCT05790720Recruiting
Propofol dosing study for older adults
This study looks at how the anesthetic drug propofol works in older adults during planned surgeries. The goal is to find the right dose for safe and effective anesthesia.
Santiago, Santiago MetropolitanAges 65–99 - NCT05514405Recruiting
Testing two anesthesia medicines to prevent confusion after surgery
This trial tests whether using remimazolam or propofol during hip or knee replacement surgery can lower the risk of postoperative delirium, a sudden, short-term confusion that can happen after anesthesia. It may help people who are at higher risk of postoperative confusion by finding the safer anesthesia approach.
SeoulAges 65–100 - NCT05303987RecruitingPhase 2
Dexmedetomidine or propofol for sleep endoscopy in children
This Phase 2 study compares two medicines used to help children sleep during a procedure called drug-induced sleep endoscopy. It’s for children with obstructive sleep apnea who are being evaluated before adenotonsillectomy, to help surgeons understand the cause of the blockage and potentially improve treatment planning.
Ann Arbor, MichiganAges 3–11 - NCT07221539Recruiting
Waking the brain with ultrasound during sedation
This study uses focused ultrasound to stimulate a deep brain region and see if it can help people wake up faster from anesthesia. Healthy volunteers will be sedated and monitored while the ultrasound is applied.
Ann Arbor, MichiganAges 18–40 - NCT05272202RecruitingEarly Phase 1
Study brain signals after median nerve stimulation during anesthesia
This early-stage study checks how brain activity changes when the median nerve is gently stimulated while you’re under general anesthesia with propofol. It may help researchers better understand brain–nerve connections and improve how these signals are measured.
BrusselsAges 18–81
Hear when a new Propofol trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for propofol?
- Yes. Clin2 currently lists 108 recruiting propofol studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a propofol trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a propofol trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.