Clinical trials
Propofol clinical trials
Below are recruiting propofol clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06570187RecruitingPhase 4
Dexmedetomidine for kidney protection in sepsis
This trial tests if dexmedetomidine, a sedative, can help protect the kidneys of critically ill patients with sepsis who develop acute kidney injury (a sudden drop in kidney function). It is for adults in the ICU who need a breathing tube or mask within 48 hours of kidney injury.
CairoAges 18–90 - NCT06573489RecruitingPhase 4
Fospropofol for laparoscopic surgery safety study
This trial tests a sedative called fospropofol during laparoscopic abdominal surgery. It aims to see if it's safe and effective for adults with longer operations.
Wuhan, HubeiAges 18–65 - NCT06577636RecruitingPhase 2
Dream induction with anesthesia for PTSD
This trial tests whether inducing dreams during light anesthesia can help treat post-traumatic stress disorder (PTSD). You'll have a low-risk procedure where doctors monitor your brain activity and guide dreams to reduce PTSD symptoms.
Stanford, CaliforniaAges 18–70 - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06733129RecruitingPhase 3
Which sleeping medicine is best for emergency intubation?
This trial compares different sleeping medicines (ketamine, propofol, and similar drugs) to see which is safest for people who need a breathing tube placed quickly in the operating room. It focuses on those at risk of stomach contents going into the lungs.
AngersAges 18–80 - NCT06744361RecruitingPhase 2
Ketamine after cardiac arrest to protect the brain
This trial tests whether the sedative drug ketamine, given after a cardiac arrest, can help protect the brain. It's for people whose heart stopped outside the hospital due to a shockable rhythm and who needed a breathing tube placed by emergency responders.
CopenhagenAges 18 years+ - NCT06844838Recruiting
Faster, Safer Awakening After Brain Surgery
This study tests a new way of giving anesthesia during elective brain surgery to help you wake up faster and safer. It uses a special monitor to guide the amount of medication so you can recover more quickly.
MilanAges 18 years+ - NCT06884657RecruitingPhase 4
Mannitol's effect on propofol levels during brain tumor surgery
This trial studies how mannitol, a medicine to reduce brain swelling, affects the levels of propofol (an anesthesia drug) in your blood during brain tumor surgery. It may help doctors adjust anesthesia doses more safely.
Çukurova, AdanaAges 18–65 - NCT06951802RecruitingPhase 4
Low-dose ketamine for pain during endometriosis surgery
This study tests whether giving a low dose of ketamine during endometriosis surgery can help reduce pain. If you qualify, you'll receive ketamine or a placebo during your procedure, and the team will check your pain levels afterward.
BernAges 18 years+ - NCT06952608RecruitingPhase 4
Ciprofol for blood pressure stability in older adults on heart medications
This study tests whether ciprofol, a newer sedative, can help prevent low blood pressure during surgery in older patients who are already taking medications for high blood pressure or heart failure (called RAS inhibitors). It may be a good option if you're 65 or older, on these medications for more than 3 months, and having abdominal surgery lasting over 2 hours.
Hangzhou, ZhejiangAges 65 years+ - NCT07028593RecruitingPhase 4
Ciprofol for heart protection during lung surgery
This trial tests if a new sedative drug, Ciprofol, can reduce heart damage after non-cardiac surgery compared to standard care. It is for people aged 45–80 having planned lung surgery (like lobe removal or wedge resection) who will stay in the hospital for at least 3 days after the procedure.
WuhanAges 40–80 - NCT07181564Recruiting
Anesthesia methods and safety in sinus surgery
This trial compares different anesthesia techniques during functional endoscopic sinus surgery to see which one protects the brain best and improves the surgical field. It may help patients understand the safest approach for their procedure.
Pátrai, AchaiaAges 18–90 - NCT07211828Recruiting
Brain activity and pain signals during anesthesia study
This study looks at how opioids and sedatives affect brain activity and pain signals in patients getting anesthesia for an ERCP procedure.
MiaoliAges 18 years+ - NCT07222007Recruiting
Induction agent choice and survival in ICU patients
This study looks at how the type of medicine used to start sedation in the surgical ICU affects early survival and recovery. It may help doctors choose safer options for critically ill patients.
Jacksonville, FloridaAges 18 years+ - NCT07259291Recruiting
Comparing two remifentanil dosing methods during anesthesia
This trial compares two ways of giving the pain medicine remifentanil during anesthesia. It looks at how well the computer models predict the right dose for each patient.
TrevisoAges 18–80 - NCT07259460Recruiting
Dexmedetomidine effects during propofol anesthesia
This study tests whether adding a sedative called dexmedetomidine changes brain activity during general anesthesia. It aims to improve how anesthesia is given.
Treviso, TVAges 18–80 - NCT00695214RecruitingPhase 2
Test with medicine-assisted sleep endoscopy for sleep apnea
This trial studies how well a procedure done while you sleep helps doctors understand the blockage causing obstructive sleep apnea and plan surgery. You may be helped if you’re an adult with sleep apnea who is considering surgical treatment.
Santa Monica, CaliforniaAges 18 years+ - NCT07000526RecruitingPhase 4
Inhaled sedation for critically ill patients on breathing machines
This trial compares inhaled isoflurane sedation to standard propofol sedation in deeply sedated patients on ventilators. It aims to see if inhaled sedation improves outcomes.
Orihuela, AlicanteAges 18–80 - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07556523RecruitingPhase 4
Recovery quality after heart valve replacement with different sedation
This study compares how well patients recover after a minimally invasive heart valve procedure (TAVR) when given different types of sedation. The goal is to find which sedation approach helps patients feel better and recover faster after the procedure.
Glenview, IllinoisAges 18–90 - NCT07557576Recruiting
Pain management approaches for children having cleft surgery
This study compares two types of anesthesia (with and without opioid painkillers) for children undergoing cleft lip or palate surgery. The goal is to see which approach better controls pain after surgery and reduces agitation as the child wakes up.
ZagrebAges 3 months–7 years - NCT07612579Recruiting
Anesthesia choice and delirium after surgery
This study compares two types of anesthesia (propofol and sevoflurane) to see which one helps prevent confusion and delirium after surgery. Delirium is a temporary state of confusion that can happen after surgery, and researchers want to understand which anesthesia approach might reduce this risk.
BerlinAges 18 years+ - NCT07161518Enrolling by invitationPhase 4
Testing focused ultrasound on the brain during sedation
This trial uses focused ultrasound to gently stimulate parts of the brain while you are under sedation. It aims to understand how this technology affects brain activity and could lead to new ways to treat brain disorders without surgery.
Palo Alto, CaliforniaAges 18–65 - NCT07080528Enrolling by invitationPhase 4
Measuring muscle relaxant duration in infants during skull surgery
This trial tests how long a muscle relaxant (rocuronium) works in infants aged 3-12 months having skull surgery for a condition called craniosynostosis. The results may help doctors give safer and more effective doses.
Debrecen, Hajdú-BiharAges 3 months–1 year
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Common questions
- Are there clinical trials for propofol?
- Yes. Clin2 currently lists 120 recruiting propofol studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a propofol trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a propofol trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.