Clinical trials
Prostate Cancer Surgery clinical trials
Below are recruiting prostate cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 449 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05568550RecruitingPhase 2
Radiation with or without olaparib for high-risk prostate cancer
This Phase 2 study tests whether adding a medicine called olaparib to radiation helps men with high-risk prostate cancer. You may receive radiation alone or radiation plus olaparib, and the study looks at whether the combination works better.
Lexington, KentuckyAges 18 years+ - NCT05381103RecruitingPhase 2/Phase 3
PSMA scan to plan prostate surgery and help protect erections
This trial tests whether using a PSMA-PET scan before prostatectomy can guide surgery in a way that helps preserve sexual function. It may be most helpful if you have certain kinds of prostate cancer and want to keep erections after surgery.
Indianapolis, IndianaAges 40–80 - NCT05488548RecruitingPhase 1
Study drug that blocks BET and CBP/p300 in advanced cancers
This Phase 1 trial tests an investigational medicine that targets BET and CBP/p300 to try to slow or control advanced, hard-to-treat cancers. You may be eligible if you have certain prostate cancer or NUT midline carcinoma, or specific blood cancers like CMML or myelofibrosis (MF), and your body functions are strong enough for chemotherapy-style treatment.
Phoenix, ArizonaAges 18 years+ - NCT05710861Recruiting
Focal HIFU versus prostate surgery: cost and quality of life
This trial compares focal HIFU (a targeted heating treatment inside the prostate) with prostate surgery, looking at overall cost and quality of life. It may help people with certain early, limited prostate cancers understand which option fits best for them.
BesançonAges 50–75 - NCT05722392Recruiting
Two-step surgery for localized prostate cancer
This trial studies a “two-step” type of prostate removal surgery for men with localized prostate cancer, focusing on whether it is safe and effective. It may help if you have certain prostate size, PSA level, and tumor features that match their criteria.
Guangzhou, GuangdongAges Any age - NCT06084338RecruitingPhase 2
Focused Radiation Therapy Without Hormone Therapy for Advanced Prostate Cancer
This trial tests whether giving focused radiation to many cancer spots (SBRT) can work without using testosterone-blocking hormone therapy. It is for men whose prostate cancer has spread and is no longer responding to low testosterone, and who have already tried one of the newer hormone drugs.
West Los Angeles, CaliforniaAges 18 years+ - NCT06111313RecruitingPhase 2
Prostate cancer trial testing targeted radiation with hormone therapy
This trial tests a new radiation approach for prostate cancer that has not spread. It combines different types of radiation with or without hormone therapy to see if this approach works better with fewer side effects.
Miami, FloridaAges 35–85 - NCT06177015RecruitingPhase 3
Darolutamide with chemo for metastatic prostate cancer
This trial tests a new way of using darolutamide (a hormone therapy) together with standard chemotherapy (docetaxel) and hormone therapy (ADT) for men with prostate cancer that has spread. The goal is to see if taking darolutamide on an intermittent schedule works as well as continuous treatment.
Nanjing, JiangsuAges 40–80 - NCT06262139RecruitingPhase 1/Phase 2
New MRI dye for high-risk prostate cancer
This trial tests a new MRI contrast dye that might help doctors see aggressive prostate cancer more clearly. It is for men with high-risk prostate cancer (Gleason 8-10) who have already had an MRI and a biopsy.
Atlanta, GeorgiaAges 18–90 - NCT06279260Recruiting
National robotic prostate surgery database study
This study collects health information from men who have had robotic surgery for prostate cancer. It aims to learn more about the outcomes of this surgery to help improve future care.
Ballarat, VictoriaAges 18–90 - NCT07048314RecruitingPhase 1/Phase 2
Stem cells for erectile dysfunction after prostate surgery
This trial tests if stem cells can help restore erectile function in men who have had prostate cancer surgery (RALP). It is for men with localized, low-risk cancer and good sexual function before surgery.
Houston, TexasAges 40–70 - NCT06330909Recruiting
Focused radiation boost for prostate cancer
This trial tests a newer, more precise radiation treatment that gives a higher dose to the main tumor while keeping radiation to the rest of the prostate the same. It is for men with intermediate- or high-risk prostate cancer who haven't had prior prostate radiation or removal.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06355076Recruiting
New Urethral Reconstruction in Robotic Prostate Removal
This trial tests a new way to rebuild the urethra during robot-assisted prostate removal surgery for prostate cancer. It may help people whose cancer hasn't spread too far or has been reduced enough for surgery.
Jinan, ShandongAges 18 years+ - NCT06398613Recruiting
Using PSMA PET scan before prostate cancer surgery
This trial is testing whether a special scan (PSMA PET/CT) before surgery can help doctors decide if you need to remove lymph nodes. It is for men with high-risk prostate cancer who are already planning to have robot-assisted prostate removal.
OsloAges 18 years+ - NCT06462495RecruitingEarly Phase 1
Comparing two PSMA PET/CT scans for prostate cancer
This trial compares two types of PET/CT scans (using different radioactive tracers) to see which is better at finding prostate cancer, tracking its return, or spotting spread. It's for people with prostate cancer or those being checked for recurrence after treatment.
Hefei, AnhuiAges 18–90 - NCT06462508RecruitingEarly Phase 1
Comparing two PET scans for prostate cancer detection
This trial compares two types of PET scans—one using a new tracer called [18F]F-PSMA-N5 and another using an existing tracer called [68Ga]Ga-PSMA-11—to see which is better at finding prostate cancer, including early signs of recurrence. If you have or are suspected of having prostate cancer, this study may help determine how advanced the disease is.
Hefei, AnhuiAges 18–90 - NCT06496256Recruiting
Barrigel gel for radiation after prostate removal
This trial tests a gel placed in the rectum during radiation therapy to protect healthy tissue after prostate removal. It is for men whose prostate cancer has come back (PSA rise) and who need radiation to the prostate bed.
Boston, MassachusettsAges 18 years+ - NCT06521710Recruiting
Nerve grafting to preserve erections after prostate removal
This trial tests if a nerve grafting technique can help preserve erectile function after robotic surgery for high-risk localized prostate cancer. It may be an option for men with good preoperative erectile function.
Montreal, QuebecAges 18 years+ - NCT06543420Recruiting
Pelvic muscle repair to improve bladder control after prostate surgery
This trial is testing a new surgical technique to help the muscles that support the bladder recover after prostate cancer surgery. It may help men who are having robot-assisted prostate removal to regain better bladder control afterward.
Beijing, Beijing MunicipalityAges 18–80 - NCT06655259RecruitingPhase 2
TURP with standard therapy for metastatic prostate cancer
This trial tests whether adding a surgery called TURP (transurethral resection of the prostate) to the usual hormone therapy and chemotherapy can help men with metastatic prostate cancer that has spread to lymph nodes, bone, or other organs. The surgery helps relieve urinary symptoms and may improve how well the cancer responds to treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06683066RecruitingPhase 1
Testing a prostate cancer drug for bioequivalence
This trial checks if a new version of the prostate cancer drug triprerelin works the same as the current one. It may be an option for men with prostate cancer who need hormone therapy.
Qingdao, ShandongAges 18 years+ - NCT06756334RecruitingEarly Phase 1
Comparing Two PET/CT Scans for Prostate Cancer
This study compares two types of PET/CT scans (using different radioactive tracers) to see which one is better at finding prostate cancer, detecting if it has come back, or spotting spread to other parts of the body. You will get both scans so doctors can compare them directly.
Hefei, AnhuiAges 18–90 - NCT06817668Recruiting
Testing a new radiation approach for prostate cancer
This study is testing a new way of giving radiation for prostate cancer, called ePUHRT, combined with a standard brachytherapy boost (a small radioactive implant placed inside the prostate). It aims to see if this approach is well-tolerated and safe for people with higher-risk prostate cancer.
Indianapolis, IndianaAges 18 years+ - NCT06820606Recruiting
Comparing two treatments for enlarged prostate
This trial compares Rezum and Urolift, two minimally invasive procedures that treat an enlarged prostate (BPH). It aims to see which one works better for men who have moderate to severe urinary symptoms.
Hong KongAges 50 years+
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Common questions
- Are there clinical trials for prostate cancer surgery?
- Yes. Clin2 currently lists 449 recruiting prostate cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.