Clinical trials
Prostate Cancer Surgery clinical trials
Below are recruiting prostate cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 463 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05956639RecruitingPhase 3
Rezvilutamide with ADT and chemo: shorter versus longer treatment
This Phase 3 trial compares two lengths of rezvilutamide treatment when given with hormone therapy (ADT) and chemotherapy for men with advanced prostate cancer. It aims to find which treatment duration works best and is safest to help control the cancer.
Nanjing, JiangsuAges 18 years+ - NCT06177015RecruitingPhase 3
Darolutamide with chemo for metastatic prostate cancer
This trial tests a new way of using darolutamide (a hormone therapy) together with standard chemotherapy (docetaxel) and hormone therapy (ADT) for men with prostate cancer that has spread. The goal is to see if taking darolutamide on an intermittent schedule works as well as continuous treatment.
Nanjing, JiangsuAges 40–80 - NCT06330909Recruiting
Focused radiation boost for prostate cancer
This trial tests a newer, more precise radiation treatment that gives a higher dose to the main tumor while keeping radiation to the rest of the prostate the same. It is for men with intermediate- or high-risk prostate cancer who haven't had prior prostate radiation or removal.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06279260Recruiting
National robotic prostate surgery database study
This study collects health information from men who have had robotic surgery for prostate cancer. It aims to learn more about the outcomes of this surgery to help improve future care.
Ballarat, VictoriaAges 18–90 - NCT06521710Recruiting
Nerve grafting to preserve erections after prostate removal
This trial tests if a nerve grafting technique can help preserve erectile function after robotic surgery for high-risk localized prostate cancer. It may be an option for men with good preoperative erectile function.
Montreal, QuebecAges 18 years+ - NCT07730203Recruiting
Better prostate scans without a catheter
This study tests a new type of CT scan that can see the urethra without needing a tube (catheter). If you're getting radiation for prostate cancer, this might make your treatment planning more comfortable and precise.
Rozzano, MilanAges 18 years+ - NCT07723248RecruitingPhase 3
Oral Rinzimetostat for Advanced Prostate Cancer After Abiraterone
This study tests an experimental pill called rinzimetostat (ORIC-944) for men with advanced prostate cancer that has spread and stopped responding to abiraterone. It may offer a new option if you have not had many other treatments yet.
Coral Springs, FloridaAges 18 years+ - NCT06655259RecruitingPhase 2
TURP with standard therapy for metastatic prostate cancer
This trial tests whether adding a surgery called TURP (transurethral resection of the prostate) to the usual hormone therapy and chemotherapy can help men with metastatic prostate cancer that has spread to lymph nodes, bone, or other organs. The surgery helps relieve urinary symptoms and may improve how well the cancer responds to treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07678489Recruiting
Prostate surgery trial keeping the urethra intact
This trial tests a robot-assisted prostate surgery method that aims to preserve the entire urethra (the tube that carries urine out of the body) to help maintain continence. It's for men with low- to intermediate-risk prostate cancer who haven't had prior prostate treatments.
DüsseldorfAges 18 years+ - NCT06683066RecruitingPhase 1
Testing a prostate cancer drug for bioequivalence
This trial checks if a new version of the prostate cancer drug triprerelin works the same as the current one. It may be an option for men with prostate cancer who need hormone therapy.
Qingdao, ShandongAges 18 years+ - NCT07623941Recruiting
Focal Therapy Registry for Localized Prostate Cancer
This registry tracks men with early-stage prostate cancer who choose focal therapy—a targeted treatment that destroys only the cancer area while preserving healthy prostate tissue. The study helps doctors understand how well this approach works and its safety.
New York, New YorkAges 40–85 - NCT07621692RecruitingPhase 1
New radioactive therapy for advanced prostate cancer
This is an early-stage trial testing a new radioactive treatment (161Tb-PSMA) for men with advanced prostate cancer that has spread and stopped responding to hormone therapy. The treatment targets cancer cells using a radioactive metal that may be more effective than older similar treatments.
TaipeiAges 20 years+ - NCT07576335RecruitingPhase 2
Prehabilitation and rehabilitation for prostate cancer surgery
This study tests a program that combines exercise, nutrition, and mental preparation before and after prostate removal surgery. The goal is to help you recover faster and keep better urinary and sexual function.
Sydney, New South WalesAges 18 years+ - NCT06398613Recruiting
Using PSMA PET scan before prostate cancer surgery
This trial is testing whether a special scan (PSMA PET/CT) before surgery can help doctors decide if you need to remove lymph nodes. It is for men with high-risk prostate cancer who are already planning to have robot-assisted prostate removal.
OsloAges 18 years+ - NCT07520916Recruiting
Mobile app education for men after prostate removal surgery
This study tests whether a smartphone app that teaches you about recovery before and after prostate cancer surgery helps prevent urinary leakage and erectile problems. You'd use the app to learn exercises and tips tailored to your recovery.
Giresun, GiresunAges 18 years+ - NCT06756334RecruitingEarly Phase 1
Comparing Two PET/CT Scans for Prostate Cancer
This study compares two types of PET/CT scans (using different radioactive tracers) to see which one is better at finding prostate cancer, detecting if it has come back, or spotting spread to other parts of the body. You will get both scans so doctors can compare them directly.
Hefei, AnhuiAges 18–90 - NCT07514065RecruitingPhase 1
TSL2109 Safety and Effectiveness Study in Advanced Cancers
This early-stage study tests a new drug called TSL2109 in patients with advanced solid cancers that haven't responded to standard treatment. Researchers want to find the right dose, understand how the body processes it, and see if it can slow or shrink tumors, with special focus on certain prostate and breast cancers.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07491198Recruiting
Head-Down Position and Eye Pressure in Prostate Surgery
This study looks at how the steep head-down position (Trendelenburg) and gas inflation during robot-assisted prostate surgery affect the sheath around the optic nerve. It aims to understand eye pressure changes to improve safety.
Izmir, İzmirAges 18 years+ - NCT05381103RecruitingPhase 2/Phase 3
PSMA scan to plan prostate surgery and help protect erections
This trial tests whether using a PSMA-PET scan before prostatectomy can guide surgery in a way that helps preserve sexual function. It may be most helpful if you have certain kinds of prostate cancer and want to keep erections after surgery.
Indianapolis, IndianaAges 40–80 - NCT07426861Recruiting
Nurse-led education before prostate surgery to reduce incontinence
This study tests whether a nurse-led education program and direct referral to a physiotherapist before prostate removal surgery can help reduce urine leakage (incontinence) after the operation. It may help you recover better bladder control.
Beaumont, DublinAges 18 years+ - NCT06820606Recruiting
Comparing two treatments for enlarged prostate
This trial compares Rezum and Urolift, two minimally invasive procedures that treat an enlarged prostate (BPH). It aims to see which one works better for men who have moderate to severe urinary symptoms.
Hong KongAges 50 years+ - NCT07348367Recruiting
Comparing two prostate cancer surgeries for low-risk patients
This trial compares two types of prostate surgery (standard removal vs. precision removal) in men with low- or intermediate-risk prostate cancer. It aims to see which surgery preserves urinary and sexual function while still effectively treating the cancer.
Detroit, MichiganAges Any age - NCT03851640RecruitingPhase 3
Study drug for advanced prostate cancer that kept spreading despite standard treatments
This Phase 3 study tests HC-1119 soft capsules in men with metastatic castration-resistant prostate cancer—cancer that keeps progressing even when testosterone is blocked. It aims to see whether the drug works better than expected and is safe, especially after prior treatments like abiraterone and/or docetaxel.
ShanghaiAges 18 years+ - NCT07259213RecruitingPhase 1/Phase 2
Study of a new drug (161Tb-RAD402) for men with advanced prostate cancer
This trial tests a new radioactive drug designed to target and destroy prostate cancer cells. It is for men whose cancer has continued to grow despite hormone therapy and other treatments like enzalutamide or abiraterone.
Wollongong, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for prostate cancer surgery?
- Yes. Clin2 currently lists 463 recruiting prostate cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.