Clinical trials
Prostate cancer clinical trials
Cancer of the prostate gland, one of the most common cancers in men. We’re tracking 1,212 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06684652Recruiting
Comparing targeted plus standard biopsies for prostate cancer diagnosis
This trial tests whether adding a targeted biopsy to a standard sextant biopsy improves the detection of prostate cancer. It is for men aged 45 to 85 who have a suspicious spot on an MRI of their prostate and have not had a biopsy before.
Beijing, Beijing MunicipalityAges 45–85 - NCT06935097Enrolling by invitation
Mediterranean diet study for Black and Hispanic men with prostate cancer
This study tests whether a Mediterranean diet can help men with prostate cancer. You'll receive guidance on following this diet to see if it improves your health.
Houston, TexasAges 18 years+ - NCT06940271Recruiting
Nerve wrap procedure during prostate surgery to help preserve erectile function
This study tests wrapping the nerves next to the prostate with a special tissue graft during prostate cancer surgery. The goal is to see if it helps keep erectile function after surgery.
Jacksonville, FloridaAges 45 years+ - NCT06915909Recruiting
Robotic prostate surgery with low pressure gas for less pain
This trial tests whether using lower gas pressure during robotic prostate surgery can reduce pain after the operation. It aims to help men recover more comfortably.
Stevenage, HertfordshireAges 18–75 - NCT04004312Recruiting
Short-course radiation slices for localized prostate cancer
This trial tests a radiation approach that delivers treatment in a small number of larger “fractions” (short-course SBRT) for prostate cancer. It may help by targeting the prostate while shortening the overall number of visits.
Montreal, QuebecAges 18 years+ - NCT04249154RecruitingPhase 2
After prostate surgery, test radiation plus hormone shots
This trial studies whether giving a shorter-course radiation plan after prostate surgery, along with hormone shots (LHRH), can improve outcomes for people with higher-risk prostate cancer. You may be eligible if your PSA (a blood marker) is either still low but high-risk by pathology, or it has started to rise again after surgery.
Montreal, QuebecAges 18 years+ - NCT06910657RecruitingPhase 1
IDOV-Immune vaccine for advanced solid tumors
This trial tests an experimental virus-based treatment for people with advanced solid tumors that have stopped responding to standard therapies. The treatment is designed to infect and destroy cancer cells while boosting the immune system.
St Louis, MissouriAges 18 years+ - NCT06904625Recruiting
Capturing tumor cells in metastatic breast or prostate cancer
This study compares different methods of capturing circulating tumor cells (CTCs) from blood samples in patients with metastatic breast or prostate cancer. It aims to improve how we detect and monitor cancer cells that have spread, which could help guide future treatment decisions.
ToulouseAges 18 years+ - NCT05796973RecruitingPhase 3
Exercise and atorvastatin for metastatic cancer outcomes
This trial tests whether a structured exercise program, along with the cholesterol medicine atorvastatin, can improve outcomes in people with metastatic prostate, breast, ovarian, or kidney cancer. It may help by reducing inflammation and supporting physical function during cancer treatment.
Tampere, Länsi-SuomiAges 18–99 - NCT06872619Enrolling by invitation
Prostate Cancer Research Registry
This registry collects information from people with prostate cancer to help researchers better understand the disease and improve future treatments.
MünsterAges 45–100 - NCT06392737Recruiting
AI-guided MRI vs routine MRI for prostate biopsy
This study tests whether an artificial intelligence tool for MRI can improve the results of targeted prostate biopsy, compared to the usual method. It could help diagnose prostate cancer more accurately with fewer needles.
Beijing, Beijing MunicipalityAges 45–85 - NCT06864533Recruiting
Chemotherapy after surgery for aggressive prostate cancer
This trial tests whether adding chemotherapy after standard treatment helps people with a very aggressive type of prostate cancer (Gleason score 9-10). It is designed for those who have not had their cancer spread to distant parts of the body and are healthy enough to handle chemotherapy.
Beijing, Beijing MunicipalityAges 18–80 - NCT06854250RecruitingPhase 2
Cryoablation and low-dose chemo for metastatic prostate cancer
This trial tests freezing prostate tumors (cryoablation) combined with a low-dose chemotherapy pill (metronomic cyclophosphamide) for men with metastatic prostate cancer. The goal is to see if this combination can slow the cancer's growth and improve outcomes.
Guangzhou, GuangdongAges 18–80 - NCT06856694Recruiting
Feedback tool to help men with prostate cancer decide on treatment
This trial tests a computer tool that analyzes your conversations with doctors. It aims to help you make a more informed choice about prostate cancer treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06844383RecruitingPhase 2
Talazoparib with or without enzalutamide for prostate cancer after prior treatment
This study tests a drug called talazoparib, either alone or combined with enzalutamide, in people with prostate cancer that has spread and has a specific genetic change. The goal is to see if this treatment can help control the cancer after previous therapies have stopped working.
Duarte, CaliforniaAges 18 years+ - NCT06835218Recruiting
Prostate cancer real-world evidence registry
This study collects information from men with prostate cancer to better understand how different treatments work in real life. It follows patients when they start a new treatment and can help improve future care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06834152Recruiting
Online adaptive radiation for localized prostate cancer
This trial tests a new way to deliver high-precision radiation to the prostate using daily MRI or CT scans to adjust the treatment based on your exact anatomy. It aims to make radiation more accurate and reduce side effects.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06828263Recruiting
Imaging markers during PSMA therapy for prostate cancer
This trial is testing a new imaging approach during treatment with a radioactive drug (Lu-PSMA) for men with advanced prostate cancer that no longer responds to hormone therapy. The goal is to see if imaging changes can help predict how well the treatment is working.
GrenobleAges 18 years+ - NCT06826924Recruiting
Fasting or ketones for prostate cancer
This trial tests whether a 7-day water-only fast or taking ketone supplements can help treat prostate cancer. You would have a biopsy before and after to see how the tumor responds.
Baltimore, MarylandAges 18 years+ - NCT06822036Recruiting
Starch powder to reduce bleeding in prostate surgery
This trial tests whether applying a dissolvable starch powder (Arister) inside the pelvis during robot-assisted prostate cancer surgery reduces post-surgery bleeding. It is for men whose surgeons plan to spare the nerves controlling erections and who have moderate erectile function beforehand.
Hamburg, Free and Hanseatic City of HamburgAges 45–68 - NCT06801236RecruitingPhase 1
A new drug for advanced prostate cancer that has stopped responding to treatment
This early-phase trial tests a new study drug called ACE-232 for men with advanced prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. It aims to see if the drug is safe and may help slow the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06785636RecruitingPhase 1/Phase 2
New drug combination for advanced prostate cancer
This study tests a new drug (pocenbrodib) alone or combined with another hormone therapy (darolutamide) for men with advanced prostate cancer that has spread. It is for those who have already tried Pluvicto and one other hormone therapy, but not yet chemotherapy.
Fountain Valley, CaliforniaAges 18 years+ - NCT05574647Recruiting
Fast prostate MRI and guided biopsy testing for prostate cancer
This study checks whether a faster prostate MRI and image-matching (image-fusion) can better find suspicious spots so doctors can target a biopsy. If you have concerning prostate exam results or PSA blood test results, you may get an MRI and, if something looks suspicious, a biopsy using MRI images.
Southend-on-Sea, EssexAges 18 years+ - NCT02543905Recruiting
Profile study for men at higher prostate cancer risk
This trial looks at how inherited risk (family history or gene findings) relates to screening and treatment for prostate cancer. If you qualify, you may be offered prostate screening tests and follow-up to see how well risk information predicts next steps.
Sutton, SurreyAges 40–69
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Common questions
- Are there clinical trials for prostate cancer?
- Yes. Clin2 currently lists 1,212 recruiting prostate cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.