Clinical trials
Prostate clinical trials
Below are recruiting prostate clinical trials, each written for real people, not researchers. We’re tracking 1,360 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04337580RecruitingPhase 2
Test a fatty-acid drug for docetaxel-resistant prostate cancer
This Phase 2 study tests whether blocking fatty-acid production can slow castration-refractory prostate cancer that has already progressed after docetaxel. It may help by targeting cancer growth when standard hormone-level treatments are no longer working.
Salisbury, North CarolinaAges 18 years+ - NCT04175431RecruitingPhase 2
PSMA or FACBC PET scan guided treatment for prostate cancer recurrence
This Phase 2 study tests using a special PET/CT scan (PSMA or FACBC) to guide treatment for prostate cancer that has come back after surgery and radiation. The goal is to see whether this scan-based approach can better target cancer in the prostate area (and help plan the right treatment).
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04075305Recruiting
Study measuring radiation treatment outcomes with an MR-Linac
This study follows what happens when radiation treatment is guided using an MR-Linac (a special machine that combines MRI imaging with radiation). It may help improve how radiation therapy is planned and assessed, especially for people who can safely have MRI scans.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03933670RecruitingPhase 2
MRI scan with special sugar to monitor prostate cancer on surveillance
This study uses a special MRI scan using “hyperpolarized” labeled pyruvate (a sugar-like substance) to see how prostate cancer may be behaving in people who are on active surveillance. It may help researchers monitor cancer without immediate treatment, by spotting changes earlier.
San Francisco, CaliforniaAges 18 years+ - NCT03784924Recruiting
Prostate MRI study to find blood and urine cancer signals
This study enrolls men who may have prostate cancer but do not yet have a diagnosis. It uses prostate MRI along with blood and urine tests to see if specific signals can help identify prostate cancer sooner.
Ann Arbor, MichiganAges 18 years+ - NCT03802851Recruiting
Laser procedure before radiation for prostate cancer symptoms
This trial looks at whether doing a prostate “laser procedure” (called HoLEP) before starting radiation and hormone therapy can improve severe urinary symptoms and reduce urine retention problems. It is for people with prostate cancer who are planning radiation plus hormone treatment and who have significant bladder/urinary trouble.
Kansas City, KansasAges 18 years+ - NCT03650595Recruiting
MRI-guided laser treatment for prostate cancer
This trial tests a minimally invasive prostate treatment using MRI guidance and a focal laser to destroy only the cancer spot (not the whole prostate). If you have low-to-intermediate risk, MRI-visible prostate cancer in a limited area, it may help control the cancer while potentially reducing treatment side effects.
Toronto, OntarioAges 40–80 - NCT03423303Enrolling by invitation
Screening test to find early prostate cancer sooner
This trial checks whether an early prostate cancer screening approach can detect clinically significant prostate cancer sooner. It may help participants catch the disease at an earlier stage when treatment can be more effective.
HelsinkiAges 50–63 - NCT03424850RecruitingPhase 1/Phase 2
Tested different radiation doses for early prostate cancer
This trial studies how safe and effective different high-dose radiation levels are for prostate cancer placed directly in the prostate (HDR brachytherapy). It may help by finding a dose that controls the cancer while keeping side effects acceptable.
St Louis, MissouriAges 18 years+ - NCT03495427RecruitingPhase 2/Phase 3
PSMA PET scan to find early prostate cancer spread
This study uses a PSMA PET scan to look for early spread of prostate cancer in men with higher-risk genetic test results (Decipher score above 0.45). It may help doctors spot metastases sooner so treatment decisions can be better targeted.
Tampa, FloridaAges 18 years+ - NCT03151629Recruiting
Registry for men with advanced prostate cancer
This study is a worldwide registry that collects health information from men with advanced prostate cancer. It may help researchers better understand disease patterns and outcomes, which can guide future treatments.
Birmingham, AlabamaAges 21 years+ - NCT03246802Recruiting
HDR brachytherapy for prostate cancer that returned after prior radiation
This trial studies a targeted, high-dose form of radiation (HDR brachytherapy) for prostate cancer that has come back after earlier radiation treatment. It aims to treat a limited (one-area) recurrence while trying to avoid serious late side effects from repeat radiation.
Kelowna, British ColumbiaAges 45 years+ - NCT02759744Enrolling by invitation
Laser treatment for certain prostate tumors guided by MRI images
This trial tests whether a precisely targeted laser procedure—guided by MRI images—can treat prostate cancer. It may help some men who have a certain type and location of tumor while aiming to avoid nearby sensitive structures.
Bethesda, MarylandAges 18–100 - NCT02594202Recruiting
Collecting prostate cancer care details and prostate tissue samples
This trial enrolls adults who are being evaluated or treated for possible or confirmed prostate cancer and allows researchers to collect prostate tissue. It may help improve understanding of prostate cancer over the course of diagnosis and standard care.
Bethesda, MarylandAges 18 years+ - NCT02526368RecruitingEarly Phase 1
Scan your prostate with special MRI using pyruvate to find high-grade cancer
This trial tests whether a specialized MRI scan using a pyruvate tracer can better detect high-grade (more aggressive) prostate cancer. It may help doctors find cancer more accurately and guide treatment decisions or targeted follow-up.
San Francisco, CaliforniaAges 18 years+ - NCT01834001Recruiting
MRI checks how prostate cancer responds to radiation
This study uses MRI scans to see how prostate cancer changes after radiation treatment, especially in the local (prostate-area) response. It may help doctors better judge treatment effectiveness and plan care more precisely.
Bethesda, MarylandAges 18–120 - NCT01050504Recruiting
Donate blood and tissue to study recurrent or metastatic cancers
This study collects and studies blood and, when possible, small tissue samples from people with prostate or bladder/urothelial cancer that has come back or spread. The goal is to better understand these cancers and support future research that may lead to better care.
Seattle, WashingtonAges 18 years+ - NCT06879041RecruitingPhase 1
Study of a radioactive drug for advanced prostate cancer
This study tests a new radioactive drug, [225Ac]-AZD2284, for men with prostate cancer that has spread and no longer responds to hormone therapy. The drug is designed to target cancer cells and deliver radiation directly to them, potentially slowing the cancer's growth.
Palo Alto, CaliforniaAges 18 years+ - NCT07751133RecruitingPhase 3
Hormone therapy dosing study for metastatic prostate cancer
This study tests different ways of giving hormone therapy to find the right dose for men with prostate cancer that has spread. It aims to help manage the disease while limiting side effects.
ManchesterAges 18 years+ - NCT07783282RecruitingPhase 1
How prostate cancer drugs affect a new medicine
This study looks at how a new medicine called fezolinetant is processed by the body when taken alongside common prostate cancer hormone treatments. It is an early-phase trial that helps researchers understand if there are any drug interactions, which could be important for future treatment options.
Plovdiv, Plovdiv ProvinceAges 50–75 - NCT07365995RecruitingPhase 3
New drug for advanced prostate cancer vs. standard chemo
This trial tests a new drug called BNT324 against the standard chemotherapy docetaxel for men with advanced prostate cancer that has stopped responding to hormone therapy. It aims to see if the new treatment can help control the cancer better.
Santa Barbara, CaliforniaAges 18 years+ - NCT07221825Recruiting
Radium-223 imaging study for men with prostate cancer
This study uses a special type of scan (quantitative SPECT) to measure how Radium-223 (Xofigo) works in your bones. It helps doctors better understand treatment for prostate cancer that has spread to the bones.
St Louis, MissouriAges 18 years+ - NCT07632742Recruiting
Two laser systems for prostate surgery: which works better?
This study compares two different laser technologies used during a minimally invasive prostate surgery called HoLEP. You'll be randomly assigned to one laser type and asked to complete brief surveys online after your procedure to help doctors understand which works best for reducing urinary symptoms.
Chicago, IllinoisAges 18–100 - NCT07677254Recruiting
Real world study of prostate cancer treatments
This study looks at real-world data from men with metastatic castration-resistant prostate cancer (mCRPC) to understand what treatments they receive and how they do. It may help doctors learn more about which treatments work best.
East Hanover, New JerseyAges 18–115
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Common questions
- Are there clinical trials for prostate?
- Yes. Clin2 currently lists 1,360 recruiting prostate studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostate trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostate trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.