Clinical trials
Pulmonary Hypertension clinical trials
Below are recruiting pulmonary hypertension clinical trials, each written for real people, not researchers. We’re tracking 247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07356778RecruitingPhase 4
Study of sotatercept for Eisenmenger syndrome patients
This trial tests a new drug called sotatercept for people with Eisenmenger syndrome or a related heart defect that hasn't been repaired. It may help if current treatments aren't working well enough.
Fukuoka, Not Required For This CountryAges 18 years+ - NCT07495774Recruiting
Pediatric pulmonary hypertension registry study
This study collects information from children with pulmonary hypertension (high blood pressure in the lungs) to better understand the condition and improve care. If your child has been diagnosed with PH, joining this registry will help doctors track their health over time.
Guangzhou, GuangdongAges Up to 18 years - NCT06373289Recruiting
Blood pressure in lung arteries and oxygen levels in preemies
This study tests whether changing oxygen targets in preterm infants with high blood pressure in the lungs (pulmonary hypertension) helps their heart and lungs work better. It may help doctors find the best oxygen levels for these babies.
Birmingham, AlabamaAges 1 month–5 months - NCT06331208Recruiting
Mechanisms of Lung Blood Vessel Problems in Heart Failure
This study looks at how heart failure affects blood vessels in the lungs. If you have heart failure with reduced pumping ability and need a heart catheterization, you may be able to join.
PragueAges 18 years+ - NCT05179876RecruitingPhase 3
Treatment access study for pulmonary hypertension when no other option
This Phase 3 study continues treatment for people with pulmonary hypertension who finished an earlier parent study and have no other approved treatment option. It tests whether continuing their current medicine can help them keep getting benefit and stay safe.
MinskAges 2 years+ - NCT04624490RecruitingPhase 1
Lung function MRI using a special gas in volunteers
This Phase 1 study tests a lung scan that uses a special gas and MRI to measure how well your lungs work. It includes healthy volunteers and people with lung disease to see how well the scan works and how safe it is.
Kansas City, KansasAges 3 years+ - NCT05372263Recruiting
Tracking safety of pulmonary hypertension medicines by computer follow-up
This study checks how safe pulmonary hypertension–targeted medicines (and some calcium-blocking medicines) are over time. It uses a computer system to follow you after diagnosis, looking at outcomes and side effects.
Beijing, Beijing MunicipalityAges 3 months–85 years - NCT07087613Recruiting
Detecting heart and lung pressure problems with a smart stethoscope
This study tests if a digital stethoscope and a simple 3-lead ECG (heart rhythm test) can detect two heart conditions: high blood pressure in the lungs (pulmonary hypertension) and low pumping strength of the heart (low ejection fraction). It's intended for adults who recently had a heart ultrasound or a heart catheterization.
O'Fallon, IllinoisAges 18 years+ - NCT06499363Recruiting
Treprostinil for pulmonary hypertension in newborns
This study collects information on how well a medicine called treprostinil works and how safe it is for newborn babies with pulmonary hypertension (high blood pressure in the lungs). It is for babies who have already received this treatment as part of their regular care.
BronAges Up to 10 months - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT07236970Recruiting
AI screening for pulmonary hypertension in scleroderma
This study uses artificial intelligence to find better ways to screen for pulmonary arterial hypertension (a type of high blood pressure in the lungs) in people with systemic sclerosis (scleroderma). The goal is to catch the condition earlier so treatment can start sooner.
Granada, AndalusiaAges 18–80 - NCT02691689Recruiting
Genetics study in families with congenital heart defects and PAH
This study looks at genes that may contribute to pulmonary arterial hypertension (PAH) in people born with certain heart “shunts” (holes between heart chambers). If you have (or your family has) ASD or VSD and PAH confirmed by a heart pressure test, you may be invited to share genetic and health information to help researchers understand risk and better target future care.
LeuvenAges 18 years+ - NCT06038630RecruitingPhase 2
Xenon gas MRI study for lung and heart health
This study uses a special MRI scan (Xenon gas imaging) to look at how well your lungs and heart are working. It is for people with certain lung conditions, those getting blood transfusions or phlebotomy, or healthy volunteers.
Durham, North CarolinaAges 18 years+ - NCT07102823Recruiting
A registry study of lung blood vessel health in COPD
This study aims to better understand how COPD affects the blood vessels in your lungs by looking at measurements from a right heart catheterization. It may help doctors identify a specific pattern of lung and heart problems in people with COPD.
GrazAges 18 years+ - NCT07814118Enrolling by invitation
Understanding how your body works during routine care
This study looks at how different body systems work together in people with various conditions and healthy volunteers. It uses routine medical tests and data to understand health better, which can help improve future care.
New York, New YorkAges 18 years+ - NCT07187206RecruitingPhase 3
Fetoscopic surgery for severe diaphragmatic hernia
This trial tests if a special surgery (FETO) done while the baby is still in the womb can improve survival for babies with a severe form of congenital diaphragmatic hernia (CDH). The surgery places a small balloon in the baby's windpipe to help the lungs grow. We are looking for pregnant women whose baby has a left-sided CDH with a lung-to-head ratio (LHR) less than 30%, or a right-sided CDH with LHR less than 45%, and whose liver is herniated into the chest.
Cincinnati, OhioAges 18–50 - NCT02986087Recruiting
FETO balloon procedure for severe congenital diaphragmatic hernia
This trial studies a fetal procedure called FETO (placing a small balloon in the baby’s windpipe) to help severe congenital diaphragmatic hernia babies develop better lungs before birth. It may help some babies whose scans suggest very limited lung growth, but it requires specific timing and pregnancy conditions.
Cincinnati, OhioAges 18–50 - NCT05937854RecruitingPhase 2
Tadalafil to help breathing in COPD with pulmonary hypertension
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Aurora, ColoradoAges 35–89 - NCT07855679Recruiting
Pulmonary embolism tracking from emergency care to long-term follow-up
This study follows people who have had a pulmonary embolism (a blood clot in the lungs) to understand their health over time and improve future care. It does not test a new treatment but collects information to learn more about recovery.
Bagno a Ripoli, TuscanyAges 18 years+ - NCT07576894Recruiting
How the Heart Responds to Exercise in COPD Patients
This study looks at how the right side of your heart responds when you exercise, in people with COPD (a chronic lung condition). The goal is to understand this response better and potentially improve treatments.
Aurora, ColoradoAges 40 years+ - NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT07312227Recruiting
Pregnancy at high altitude study
This study follows pregnant women living at high altitude in Bolivia to understand how pregnancy differs from those at sea level. It may help improve care for mothers and babies in high-altitude regions.
Boston, MassachusettsAges 18–45 - NCT04930289Enrolling by invitation
Lung transplant registry for better donor lung preservation
This study builds a worldwide database to track and improve how donor lungs are preserved before transplant. Your information may help doctors choose and manage donor lungs more effectively.
Phoenix, ArizonaAges Any age - NCT03138863Recruiting
FETO surgery to help a baby’s lungs in left diaphragmatic hernia
This trial studies a specialized pregnancy procedure (FETO) done to help babies with a defect in the diaphragm called congenital diaphragmatic hernia (CDH) grow better lungs before birth. It may help by improving lung development, based on how severe the baby’s lung underdevelopment looks on ultrasound, and it requires close follow-up at the study hospital.
Miami, FloridaAges 18–50
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Common questions
- Are there clinical trials for pulmonary hypertension?
- Yes. Clin2 currently lists 247 recruiting pulmonary hypertension studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pulmonary hypertension trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pulmonary hypertension trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Pulmonary Arterial Hypertension
- Chronic Thromboembolic Pulmonary Hypertension
- Pulmonary Artery Hypertension
- Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)
- Idiopathic Pulmonary Arterial Hypertension
- Pulmonary Hypertension Due to Lung Diseases and Hypoxia
- Pulmonary Hypertension (Diagnosis)
- Pulmonary Hypertension Due to Left Heart Disease
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.